Results 131 to 140 of about 849,024 (375)

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

open access: yesAdvanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang   +9 more
wiley   +1 more source

Immune restoration in human immunodeficiency virus and hepatitis C virus coinfected patients after highly active antiretroviral therapy

open access: yesBrazilian Journal of Infectious Diseases, 2013
Objective: To evaluate the influence of hepatitis C virus on immunological and virological responses after highly active antiretroviral therapy initiation in human immunodeficiency virus/hepatitis C virus coinfected patients compared to monoinfected ...
Vicente Sperb Antonello   +4 more
doaj  

Seroprevalence of hepatitis B, C, and its associated risk factors among clinically suspected patients attending poly and Maraki Health Centers, Gondar City, North West Ethiopia

open access: yesSAGE Open Medicine
Background: Hepatitis B and C viruses are major global health problems with a high mortality rate, mostly due to serious liver diseases such as liver cirrhosis, liver failure, and hepatocellular carcinoma. The objective of this study was to determine the
Solomon Tesfaye   +4 more
doaj   +1 more source

Prevalence and associated factors of Hepatitis C virus and human immunodeficiency virus infections among voluntary counseling and testing clients attending private health facilities in Bahir Dar city, North West Ethiopia 2014

open access: yesBMC Research Notes, 2019
Objective Although incredible progress has been made in treatment and prevention of Hepatitis C virus and human immunodeficiency virus infections, the epidemic continues to spread in developing nations.
Zena Ameha   +3 more
doaj   +1 more source

CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou   +15 more
wiley   +1 more source

Seroprevalence of hepatitis B virus and its co-infection with hepatitis D virus and hepatitis C virus in Iranian adult population [PDF]

open access: yes, 2007
Context: Hepatitis B virus (HBV) infection is one of the most prevalent public health problems worldwide (especially in developing countries). Aims: This study was carried out to determine the seroprevalence of HBV and its co-infection with hepatitis D ...
Abbasali, K.   +7 more
core  

Osteopenic occult vertebral fracture is associated with poor oncological outcome in patients with hepatocellular carcinoma after hepatic resection

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Osteopenic occult vertebral fracture (OVF) was associated with poor long‐term outcomes in patients with HCC after hepatic resection. Osteopenic OVF had a poorer prognosis than that of patients with either osteopenia or OVF. Abstract Background Although osteopenia has been associated with poor outcomes in patients with hepatocellular carcinoma (HCC ...
Koichiro Haruki   +9 more
wiley   +1 more source

Hepatitis C III. Estudio laparoscópico, histológico y niveles séricos de alanina aminotransferasa en 160 pacientes seropositivos al virus de la hepatitis C Hepatitis C III. Laparoscopic and histological study and serum levels of alanine aminotransferase in 160 HCV seropositive patients

open access: yesRevista Cubana de Investigaciones Biomédicas, 2005
Se realizó el estudio laparoscópico, histológico y su correlación con el comportamiento de los niveles séricos de alanina aminotransferasa en 160 pacientes seropositivos al virus hepatitis C, que asistieron a la consulta externa del Departamento de ...
Jorge Valdés Moreno   +2 more
doaj  

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