Results 131 to 140 of about 1,173,658 (399)
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source
Seroprevalence of hepatitis E virus in chronic hepatitis C in Brazil
Background and aims: Hepatitis E virus infection in patients with underlying chronic liver disease is associated with liver decompensation and increased lethality.
Guilherme Bricks +9 more
doaj +1 more source
The hepatitis C virus: Overview [PDF]
Our knowledge of hepatitis C virus (HCV) dates only from 1975, when non- A, non-B hepatitis was first recognized. It was not until 1989 that the genome of the virus was first cloned and sequenced, and expressed viral antigens used to develop serological assays for screening and diagnosis.
openaire +2 more sources
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
Hepatitis C virus proteins [PDF]
Hepatitis C virus (HCV) encodes a single polyprotein, which is processed by cellular and viral proteases to generate 10 polypeptides. The HCV genome also contains an overlapping +1 reading frame that may lead to the synthesis of an additional protein.
openaire +2 more sources
Parabiosis, Assembloids, Organoids (PAO)
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
Aspek Virologi Hepatitis C [PDF]
Hepatitis C resembles hepatitis B epidemiologically and clinically, but not virologically. Hepatitis C virus (HCV) is an RNA virus, it does not integrate into the genome of hepatocyte, the hypervariability of glycoproteins in its envelop makes the host ...
Widura, W. (Widura)
core
The epidemiology of hepatitis C virus in Iran: Systematic review and meta-analyses [PDF]
Sarwat Mahmud +2 more
openalex +1 more source
Assessment of Plasma Vitronectin as Diagnostic and Prognostic Marker of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Cirrhosis [PDF]
Salem Youssef Mohamed +3 more
openalex +1 more source
Pathogenesis of hepatitis C virus
Hepatitis C virus (HCV) infects approximately 170 million people worldwide including 2 million in Japan and induces serious chronic hepatitis that results in the development of steatosis, cirrhosis and ultimately hepatocellular carcinoma. The current combination therapy using pegylated interferon alpha and a nucleotide analogue ribavirin achieved a ...
Kohji, Moriishi, Yoshiharu, Matsuura
openaire +3 more sources

