Results 61 to 70 of about 1,110,405 (395)

Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus [PDF]

, 2014
In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been ...
Hague, Charlotte V., Liefhebber, Jolanda M.P., McLauchlan, John, Wakelam, Michael J.O., Zhang, Qifeng   +4 more
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Hepatitis C virus core antigen assay: can we think beyond convention in resource limited settings?

Brazilian Journal of Infectious Diseases, 2013
Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period.
Anita Chakravarti, Mayank S. Chauhan, Gaurav Dogra, Sayantan Banerjee   +3 more
doaj   +2 more sources

Mother-to-child transmission of human immunodeficiency virus, hepatitis B virus and hepatitis C virus among pregnant women with single, dual or triplex infections of human immunodeficiency virus, hepatitis B virus and hepatitis C virus in Nigeria: A systematic review and meta-analysis

SAGE Open Medicine, 2022
Objectives: To systematically review literature and identify mother-to-child transmission rates of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus among pregnant women with single, dual, or triplex infections of human ...
George Uchenna Eleje, Chinyere Ukamaka Onubogu, Preye Owen Fiebai, Ikechukwu Innocent Mbachu, Godwin Otuodichinma Akaba, Olabisi Morebise Loto, Hadiza Abdullahi Usman, Ayyuba Rabiu, Moriam Taiwo Chibuzor, Rebecca Chinyelu Chukwuanukwu, Ngozi Nneka Joe-Ikechebelu, Chike Henry Nwankwo, Stephen Okoroafor Kalu, Chukwuanugo Nkemakonam Ogbuagu, Shirley Nneka Chukwurah, Chinwe Elizabeth Uzochukwu, Ijeoma Chioma Oppah, Aishat Ahmed, Richard Obinwanne Egeonu, Chiamaka Henrietta Jibuaku, Samuel Oluwagbenga Inuyomi, Bukola Abimbola Adesoji, Ubong Inyang Anyang, Uchenna Chukwunonso Ogwaluonye, Ekene Agatha Emeka, Odion Emmanuel Igue, Ogbonna Dennis Okoro, Prince Ogbonnia Aja, Chiamaka Perpetua Chidozie, Hadiza Sani Ibrahim, Fatima Ele Aliyu, Aisha Ismaila Numan, Solace Amechi Omoruyi, Osita Samuel Umeononihu, Chukwuemeka Chukwubuikem Okoro, Ifeanyi Kingsley Nwaeju, Arinze Anthony Onwuegbuna, Eric Okechukwu Umeh, Sussan Ifeyinwa Nweje, Lydia Ijeoma Eleje, Ifeoma Clara Ajuba, David Chibuike Ikwuka, Emeka Philip Igbodike, Chisom God’swill Chigbo, Uzoamaka Rufina Ebubedike, Chigozie Geoffrey Okafor, Nnaedozie Paul Obiegbu, Ibrahim Adamu Yakasai, Oliver Chukwujekwu Ezechi, Joseph Ifeanyichukwu Ikechebelu,   +50 more
doaj   +1 more source

Emerging Cases of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection Among Narcotics Abusers in Pondok Indah Hospital, Jakarta [PDF]

, 2005
Background: Narcotics and psychoactive substances abuse, particularly by intravenous route, currently is a major health problem affecting young Indonesian people.
Aulia, C. (Chaidir)
core  

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Identification of a Novel Hepatitis C Virus Genotype From Punjab, India: Expanding Classification of Hepatitis C Virus Into 8 Genotypes

Journal of Infectious Diseases, 2018
Background Hepatitis C virus (HCV) exhibits great genetic diversity and is classified into 7 genotypes (GTs), with varied geographic prevalence. Until the recent development of pangenotypic direct-acting antiviral regimens, the determination of HCV GT ...
S. Borgia, C. Hedskog, Bandita Parhy, R. Hyland, L. Stamm, D. Brainard, M. Subramanian, J. Mchutchison, H. Mo, E. Svarovskaia, S. Shafran   +10 more
semanticscholar   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

Strong correlation by ultrasonography of hepatomegaly and the presence of co-infection in HIV/HCV cirrhotic patients

Brazilian Journal of Infectious Diseases, 2013
Objectives: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients.
Denise Cerqueira Paranaguá Vezozzo, Maria Cassia Mendes-Correa, Marlone Cunha-Silva, Mónica Viviana Alvarado-Mora, João Ítalo Dias França, José Luiz Sebba, Antonio Carlos Nicodemo, Claudia P.M.S. Oliveira, Flair José Carrilho   +8 more
doaj   +2 more sources

Bioinformatics Techniques used in Hepatitis C Virus Research

Journal of Pure and Applied Microbiology, 2017
Hepatitis C is widely spread and induces life threatening situations. Researchers from various fields have developed vaccine, but they are not that effective because of the variation in genotype of Hepatitis virus and also not much affordable.
Vikas Kaushik, Bhupender Singh, Joginder Singh   +2 more
doaj   +1 more source