Results 71 to 80 of about 612,801 (299)

Human immunodeficiency virus and hepatitis C virus/hepatitis B virus co-infection in Southern Brazil: clinical and epidemiological evaluation

Brazilian Journal of Infectious Diseases, 2014
Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis.
Sonia Mara Raboni, Felipe Francisco Tuon, Nayara Carvalho Polido Beloto, Henrique Demeneck, Andre Oliveira, Denis Largura, Andressa Gervasoni Sagrado, Bárbara Perdonsini Lima, João Paulo Franzoni, Maria Lucia Pedroso   +9 more
doaj   +1 more source

Influence of hepatitis G virus infection on liver disease [PDF]

, 2018
The influence of hepatitis G virus (HGV) infection on disease activity in hepatitis C related and unrelated liver disease was investigated in 254 individuals using an EIA polymerase chain reaction assay for HGV. One hundred patients had chronic hepatitis
Battegay, M., Bühler, H., Diamantis, I., Fasler-Kan, E., Gyr, K., Hirsch, H., Koulentaki, M., Kouroumalis, E., Schmid, P.   +8 more
core  

Mathematical analysis of virus infectious diseases by ordinary differential equations [PDF]

, 2000
Some mathematical models describing interaction of virus and cells in vivo are reviewed. Similar models using systems of ordinary differential equations can be used for the analysis of dynamics of virus and cells for different kinds of virus.
Kajiwara, Tsuyoshi, Sasaki, Toru
core   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Natural reservoirs for homologs of hepatitis C virus

Emerging Microbes and Infections, 2014
Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. Hepatitis C virus infection causes acute and chronic liver disease, including chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Stephanie Pfaender, Richard JP Brown, Thomas Pietschmann, Eike Steinmann   +3 more
doaj   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Hepatite crônica por vírus C: Parte 1. Considerações gerais Hepatitis C virus: Part 1. General considerations

Arquivos de Gastroenterologia, 2000
O vírus da hepatite C foi identificado em 1989 como sendo o principal agente causador das hepatites não-A não-B e o seu reconhecimento como agente de alta prevalência nas infecções pós-tranfusionais e/ou uso de derivados do sangue ou em associação com o ...
Vinício Paride CONTE
doaj   +1 more source

Hepatitis C virus, cholesterol and lipoproteins--impact for the viral life cycle and pathogenesis of liver disease. [PDF]

, 2013
Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma.
Agnello, Aizaki, Amako, Amako, Anderson, Atsukawa, Bader, Bishop, Boulant, Bradley, Bradley, Brasaemle, Bulankina, Calland, Catherine Schuster, Chhatwal, Chojkier, Ciesek, Clark, Dallinga-Thie, Daniel Felmlee, Dao Thi, Dienes, Enjoji, Esau, Forde, Fraser, Goldwasser, Grove, Haid, Harrison, Herker, Hijikata, Hirata, Hsu, Huang, Icard, Ishibashi, Jopling, Kaito, Kanto, Koutsoudakis, Lambert, Lanford, Lin, Lindenbach, Mancone, Martin, Marzouk, Mathieu Lefevre, McHutchison, Meex, Meunier, Miyanari, Mohamed Hafirassou, Nahmias, Nakamuta, Nishimura, Packard, Pecheur, Petit, Poynard, Prentoe, Pumeechockchai, Ramcharran, Reiss, Rocha-Perugini, Roe, Romero-Brey, Sakamoto, Sarasin-Filipowicz, Scholtes, Schuster, Serfaty, Sezaki, Shavinskaya, Shi, Shimakami, Stanford, Targett-Adams, Thomas Baumert, Thomssen, Tsai, Voisset, Wakita, Weng, Westin, Ye, Zeisel   +88 more
core   +7 more sources

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source