BACKGROUND: Accurately identifying cases of hepatitis C virus has important medical and public health consequences. In the setting of rising hepatitis C virus prevalence and highly effective treatment with direct-acting antivirals, the Society for ...
Sarah Boudova, MD, PhD +2 more
doaj +1 more source
Natural reservoirs for homologs of hepatitis C virus
Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. Hepatitis C virus infection causes acute and chronic liver disease, including chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Stephanie Pfaender +3 more
doaj +1 more source
IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic Hepatitis C virus infection in a European cohort: A cross-sectional study [PDF]
Background To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-
Hellard, M +159 more
core +1 more source
Epidemiological Characteristics of Hepatitis C Patients Attending a Tertiary Care Hospital
Background: Hepatitis C infection is a major public health concern in Nepal. Epidemiological information on hepatitis C virus along with the status of co-infection with hepatitis B virus and human immunodeficiency virus is essential to controlling the ...
Hari Prasad Kattel +7 more
doaj +1 more source
O vírus da hepatite C foi identificado em 1989 como sendo o principal agente causador das hepatites não-A não-B e o seu reconhecimento como agente de alta prevalência nas infecções pós-tranfusionais e/ou uso de derivados do sangue ou em associação com o ...
Vinício Paride CONTE
doaj +1 more source
Determinants of hepatitis C virus clinical outcomes [PDF]
Hepatitis C VIruS (HCY) infection is characterized by a broad spectrum of clinical outcomes. An estimated 14%-46% of individuals exposed to HCY are able to clear the virus, while the other portion develops chronic ...
Yee, Leland Jonathan
core +1 more source
Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity [PDF]
Aim: Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined.
Kronenberger Bernd +26 more
core +2 more sources
Hepatitis C is a global health problem caused by infection with the hepatitis C virus. Although representative prevalence data are not available from many countries, available data indicate that approximately 3% of the world's population is infected with
A.R. ZANETTI +1 more
core +1 more source
Phylogenetic analysis of the emergence of main hepatitis C virus subtypes in São Paulo, Brazil
Background: It is recognized that hepatitis C virus subtypes (1a, 1b, 2a, 2b, 2c and 3a) originated in Africa and Asia and spread worldwide exponentially during the Second World War (1940) through the transfusion of contaminated blood products, invasive ...
Anna Shoko Nishiya +9 more
doaj +1 more source
A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population [PDF]
Background: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes.
Müllenbach, Roman +20 more
core +2 more sources

