Results 161 to 170 of about 149,243 (305)

Bringing Gene Therapy Into Real World Clinical Practice

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach   +2 more
wiley   +1 more source

Beyond Standard Half‐Life: Real‐world Pharmacokinetics of Efanesoctocog Alfa in a Single Centre

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Efanesoctocog alfa (EFA) is an ultra–extended half‐life factor VIII (FVIII) developed to address limitations of conventional prophylaxis in haemophilia A. Although the XTEND trials reported low interindividual pharmacokinetic (PK) variability, real‐world data remain important to better characterize PK profiles across patient ...
Laurent Sattler   +6 more
wiley   +1 more source

Hepatitis C virus (HCV) infection in Malaysia: findings from a nationwide cross-sectional study. [PDF]

open access: yesLancet Reg Health West Pac, 2023
Muhammad EN   +6 more
europepmc   +1 more source

Hepatitis C Virus (HCV)

open access: yesTransfusion Medicine and Hemotherapy, 2005
openaire   +1 more source

UK Infected Blood Inquiry–An Historical Appraisal

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source

Characterization of near-complete human <i>Pegivirus</i> 2 (HPgV-2) genomes in individuals co-infected with hepatitis C virus (HCV) in Cameroon. [PDF]

open access: yesMicrobiol Resour Announc
Mounchili-Njifon A   +13 more
europepmc   +1 more source

Cytokine profile and viral diversity in the early seronegative stage of community-acquired hepatitis C virus (HCV) infection. [PDF]

open access: yesSci Rep, 2023
Radkowski M   +8 more
europepmc   +1 more source

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