Results 41 to 50 of about 149,243 (305)

Modern pharmacotherapy of chronic hepatitis C depending on the genotype of the hepatitis C virus [PDF]

Annals of Mechnikov's Institute, 2019
Hepatitis C is an infectious disease of the liver caused by the hepatitis C virus (HCV), which affects the liver and causes inflammation. This virus can cause both acute and chronic course of hepatitis in (70-80% of patients), which can vary according to
I Kyreev, N Zhabotynska
doaj   +2 more sources

Lipid metabolism and HCV infection [PDF]

, 2010
Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body.
Boulant, Steeve, Paul Targett-Adams, Targett-Adams, Paul, Douglas, Mark W., McLauchlan, John, Steeve Boulant, John McLauchlan, Mark W. Douglas   +7 more
core   +1 more source

The Natural History of Hepatitis C Virus (HCV) Infection [PDF]

International Journal of Medical Sciences, 2006
Hepatitis C virus (HCV) is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma, as well as the most common indication for liver transplantation in many countries. Although the incidence of hepatitis C infection has dramatically decreased during the past decade, the worldwide reservoir of chronically infected persons is ...
Chen, Stephen L, Morgan, Timothy R
openaire   +4 more sources

Acute Coinfection with Hepatitis B and Hepatitis C Viruses

Canadian Journal of Gastroenterology, 2005
Acute coinfection of hepatitis B virus (HBV) and hepatitis C virus (HCV) is rare. The few previously reported cases all describe acute HBV followed by acute HCV, leading to HBV clearance but chronic HCV.
Brian M Yan, Samuel S Lee
doaj   +1 more source

Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection

Annals of Clinical Microbiology and Antimicrobials, 2005
Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection is not uncommon as a result of similar routes of infection. Patients who are coinfected represent a unique group with diverse serologic profiles.
Keeffe Emmet B, Crockett Seth D
doaj   +1 more source

HCV-related burden of disease in Europe : a systematic assessment of incidence, prevalence, morbidity, and mortality [PDF]

, 2009
Background Hepatitis C virus (HCV) is a leading cause of chronic liver disease, end-stage cirrhosis, and liver cancer, but little is known about the burden of disease caused by the virus.
Mühlberger, Nikolai, Uwe Siebert, Nikolai Mühlberger, Stefan Zeuzem, Sroczynski, Gaby, Ruth Schwarzer, Siebert, Uwe, Lettmeier, Beate, Schwarzer, Ruth, Gaby Sroczynski, Zeuzem, Stefan, Beate Lettmeier   +11 more
core   +1 more source

Hepatitis C virus (HCV) in children and adolescent hemophiliacs [PDF]

Jornal de Pediatria, 1998
OBJECTIVE: To evaluate the prevalence of infection by HCV among hemophiliacs in the State of Pará (Brazil), and its possible relation to hepatic enzymes serum level, type of hemophilia involved, age, level of severity, kinds and combinations of treatment, as well as date in which treatment with hemoderivates was started.METHODS: Cross-sectional ...
R C, Succi, G, Bensabath, M C, Soares, A S, Saraiva, L V, Peres   +4 more
openaire   +2 more sources

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection

, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy, Battegay, Manuel, E. Freitas, Weber, R., Furrer, H., Jeffrey, G., James, Ian, Park, Lawrence P, Swiss HIV Cohort Study,, G. Jeffrey, Battegay, M., Jeffrey, Gary, Herrmann, S., James, I., Weber, R., Battegay, M., Chapman, R., S. Herrmann, Furrer, Hansjakob, Telenti, Amalio, Freitas, E., Telenti, A., Lucas, M., M. Lucas, null null, I. James, Weber, Rainer, Telenti, A., Lucas, M., Freitas, Elizabeth, H. Furrer, Cheng, W., Jeffrey, G., Gaudieri, S., S. A. Mallal, Park, P., Freitas, E., Cheng, W., K. Pfafferott, Pfafferott, K., S. Gaudieri, R. Weber, Naidoo, Kiloshni, A. Rauch, Pfafferott, K., Mallal, Simon A, L. P. Park, Rauch, A., Chapman, R., A. Telenti, Pfafferott, Katja, R. Chapman, Lucas, Michaela, M. Battegay, Park, L.P., Naidoo, K., Herrmann, Susan, K. Naidoo, Furrer, H., Rauch, Andri, Park, L. P., W. Cheng, Herrmann, S., Naidoo, K., Chapman, Russell, Rauch, A., Mallal, S.A., Gaudieri, S., Mallal, S. A., James, I., Gaudieri, Silvana   +70 more
core   +1 more source

Hepatitis C virus infection epidemiology among people who inject drugs in Europe: a systematic review of data for scaling up treatment and prevention. [PDF]

, 2014
BACKGROUND: People who inject drugs (PWID) are a key population affected by hepatitis C virus (HCV). Treatment options are improving and may enhance prevention; however access for PWID may be poor.
Mcdonald, B, Hope, V, Basso, M, Eramova, I, Abel-Ollo, Katri, Sperle, Ida, Michot, I, Sperle, Ide, Hatzakis Angelos, Van Houdt, Sabine, Ferri, Marica, Griffiths, Paul, Lazarus Jeffrey V., Vickerman Peter, Částková, Jitka, Rosińska, Magdalena, Tarjan, A, Maria Prins, Aleixandre, Noelia Llorens, Vivian D. Hope (605401), Klavs, I, Fouchard, Jan, Brummer-Korvenkontio, Henrikki, Grady, Bart, Matheï, Catharina, Brummer-Korvenkontio, H, Berglund, T, Kantzanou Maria, Ncube, F, Lopes, Sofia, Eramova, Irina, Struzik, M, Catharina Matheï (605402), Kostrikis, L, Abagiu, Adrian Octavian, Vickerman, P, Fouchard, J, Goldberg, David, Jauffret-Roustide, Marie, Rehak, V, Fotsiou, Nasia, Mravcik, V, Caplinskiene, Irma, Folch, Cinta, Fotiou, A, Melillo, Jackie, Kustec, T, Hobstová, Jiřina, Lazarus, JV, Lazarus, Jeffrey V., Bravo, Maria Jose, Tarján, Anna, Mathei, C, Brisacier, A-C, Prins, Maria, Demanuele, Carlo Olivari, Isabelle Giraudon, EK, Wiessing, Lucas, Fotiou, Anastasios, Martins, Helena Cortes, Nechanska, B, Hope, Vivian D., Hobstova, J, Marica Ferri (605396), Grady, B, Wiessing, L, Bollaerts, Kaat, Giraudon, Isabelle, Rosinska, M, Fotsiou, N, Bogdanova, V, Struzik, Marta, Hutchinson, Sharon, Cullen, Katelyn J., Wiessing Lucas, Ruta, S, Kustec, Tanja, Catharina Matheï, Vilar, G, Hutchinson, S, Bogdanova, Violeta, Croes, Esther, Op De Coul, Eline, Ida Sperle (605399), Origer, A, Michot, Isabelle, Klavs, Irena, Palladino, C, Angelos Hatzakis (146074), Hatzakis, Angelos, Peter Vickerman, Nesheva, E, Katelyn J Cullen, Lazarus, Jeffrey V, Camilleri, M, Tallo, Tatjana, Brisacier, Anne Claire, Hope Vivian D., Martins, HC, Bollaerts, K, Hope, Vivian D, Goldberg, D, Cullen, KJ, Prins, M, Maria Prins (339491), Gómez, Rosario Sendino, Platt, Lucy, Kantzanou, Maria, EMCDDA DRID group, Hotho, Daphne, Van Houdt, S, Martins, M, Cullen, Katelyn J, Low, Andrea, Thornton, Lelia, Hutchinson, Sharon; id_orcid, Prins Maria, Palladino, Claudia, Tefanova, Valentina, Resende, Maria Emília, Resende, E, Marica Ferri, Kalamara, Eleni, Galvin, B, Karnite, A, Gomez, RS, Zimmermann, R, Ferri, M, Strandberg, J, Bart Grady (605397), Tallo, T, Busch, M, Folch, C, Gazdag, Gábor, Strandberg, Joakim, Jeffrey V Lazarus, Maria Kantzanou (605398), Jeffrey V. Lazarus (250583), Grady Bart, Abel-Ollo, K, Mcdonald, Bethan, Nechanská, Blanka, Lopes, S, Castkova, J, Maria Kantzanou, Ferri Marica, Kopilovic, B, Ruta, Simona, Vivian D. Hope, Gazdag, G, Duran, Domingos, Galvin, Brian, Groshkova, Teodora, Arama, V, Caplinskiene, I, Jeffrey V. Lazarus, Ida Sperle, Kantzanou, M, Croes, E, Garavan, C, Busch, Martin, Cruciani, Mario, Berglund, Torsten, Origer, Alain, Vilar, Graça, Melillo, J, Kopilovic, Boris, Řehák, Vratislav, Hope, VD, Cullen Katelyn J., Low, A, Matheï Catharina, Martins, Mário, Vicente, J, Angelos Hatzakis, Sperle, I, Nesheva, Elmira, Mravčík, Viktor, Platt, L, Demanuele, CO, Ncube, Fortune, Cruciani, M, Zimmermann, Ruth, Tefanova, V, Lucas Wiessing (483360), Lucas Wiessing, Thornton, L, Aleixandre, NL, Groshkova, T, Arama, Victoria, Bravo, MJ, Katelyn J. Cullen (605400), Jauffret-Roustide, M, Abagiu, AO, Sperle Ida, Op de Coul, E, Vivian D Hope, Duran, D, Kostrikis, Leontios, Karnite, Anda, Hotho, D, Yury E. Khudyakov, Bart Grady, Vickerman, Peter, BASSO, MONICA, Griffiths, P, Vicente, Julian, Peter Vickerman (210007), Katelyn J. Cullen, Hatzakis, A, Camilleri, Moses   +210 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source