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Droplet Digital PCR: A Powerful Tool for Accurate Quantification of Hepatitis D Virus RNA Levels and Verification of Detection Limits. [PDF]
J Viral HepatSandmann L +9 more
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JAMA, 2023
ImportanceHepatitis D virus (HDV) infection occurs in association with hepatitis B virus (HBV) infection and affects approximately 12 million to 72 million people worldwide. HDV causes more rapid progression to cirrhosis and higher rates of hepatocellular carcinoma than HBV alone or hepatitis C virus.ObservationsHDV requires HBV to enter hepatocytes ...
Francesco, Negro, Anna S, Lok
+5 more sources
ImportanceHepatitis D virus (HDV) infection occurs in association with hepatitis B virus (HBV) infection and affects approximately 12 million to 72 million people worldwide. HDV causes more rapid progression to cirrhosis and higher rates of hepatocellular carcinoma than HBV alone or hepatitis C virus.ObservationsHDV requires HBV to enter hepatocytes ...
Francesco, Negro, Anna S, Lok
+5 more sources
Current Treatment Options in Gastroenterology, 2007
The hepatitis delta virus (HDV) is a defective RNA virus that requires the help of hepatitis B virus (HBV) for virion assembly and penetration into hepatocytes. Thus, it can only cause disease in individuals who carry HBV. HDV infection is present worldwide, predominantly in tropical and subtropical areas.
Elif S, Koytak +2 more
openaire +2 more sources
The hepatitis delta virus (HDV) is a defective RNA virus that requires the help of hepatitis B virus (HBV) for virion assembly and penetration into hepatocytes. Thus, it can only cause disease in individuals who carry HBV. HDV infection is present worldwide, predominantly in tropical and subtropical areas.
Elif S, Koytak +2 more
openaire +2 more sources
Journal of Pediatric Gastroenterology and Nutrition, 2016
Sono discussi alcuni aspetti dell'infezione da virus HDV in eta ...
MAGGIORE, Giuseppe +1 more
openaire +3 more sources
Sono discussi alcuni aspetti dell'infezione da virus HDV in eta ...
MAGGIORE, Giuseppe +1 more
openaire +3 more sources
Journal of Pediatric Gastroenterology and Nutrition, 2015
ABSTRACTHepatitis D virus (HDV) is an uncommon, defective, single‐stranded circular RNA virus that is dependent on the hepatitis B virus’ surface antigen envelope proteins for transmission. It is highly pathogenic and associated with high rates of progression to cirrhosis and associated complications.
Megan M, Xue +2 more
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ABSTRACTHepatitis D virus (HDV) is an uncommon, defective, single‐stranded circular RNA virus that is dependent on the hepatitis B virus’ surface antigen envelope proteins for transmission. It is highly pathogenic and associated with high rates of progression to cirrhosis and associated complications.
Megan M, Xue +2 more
openaire +2 more sources
Seminars in Liver Disease, 2012
Hepatitis D occurs worldwide. The major victims of the hepatitis D virus (HDV) are individuals carrying the hepatitis B surface antigen (HBsAg); around 5% of the HBsAg carriers in the world are infected also by HDV. With the implementation of a hepatitis B virus (HBV) vaccination since the 1990s, the incidence of hepatitis D has consistently declined ...
Mario, Rizzetto, Alessia, Ciancio
openaire +2 more sources
Hepatitis D occurs worldwide. The major victims of the hepatitis D virus (HDV) are individuals carrying the hepatitis B surface antigen (HBsAg); around 5% of the HBsAg carriers in the world are infected also by HDV. With the implementation of a hepatitis B virus (HBV) vaccination since the 1990s, the incidence of hepatitis D has consistently declined ...
Mario, Rizzetto, Alessia, Ciancio
openaire +2 more sources
Journal of Viral Hepatitis, 2005
Summary. Delta virus related chronic hepatitis is difficult to treat. The response toα‐interferon (IFN), which still represents the only therapy for chronic hepatitis D, varies widely and occurs at different times from the beginning of treatment. The rate of response is proportional to the dose of IFN, with 9 million units (MU) three times a week being
G A, Niro, F, Rosina, M, Rizzetto
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Summary. Delta virus related chronic hepatitis is difficult to treat. The response toα‐interferon (IFN), which still represents the only therapy for chronic hepatitis D, varies widely and occurs at different times from the beginning of treatment. The rate of response is proportional to the dose of IFN, with 9 million units (MU) three times a week being
G A, Niro, F, Rosina, M, Rizzetto
openaire +2 more sources
Seminars in Liver Disease, 2018
AbstractNew therapeutic strategies to treat chronic hepatitis D are directed to deprive the hepatitis D virus (HDV) of functions necessary to complete its life cycle that are provided by the hepatitis B virus (HBV) and by the host. Current options are (1) the block by the synthetic peptide Myrcludex B of HBV surface antigen (HBsAg) entry into cells ...
openaire +2 more sources
AbstractNew therapeutic strategies to treat chronic hepatitis D are directed to deprive the hepatitis D virus (HDV) of functions necessary to complete its life cycle that are provided by the hepatitis B virus (HBV) and by the host. Current options are (1) the block by the synthetic peptide Myrcludex B of HBV surface antigen (HBsAg) entry into cells ...
openaire +2 more sources
Liver International, 2011
AbstractMore than 30 years after Mario Rizzetto and colleagues described a new antigen in livers of HBsAg‐positive patients called the “delta antigen”, a re‐emerging interest in hepatitis delta is currently observed. The state‐of‐the art on basic and clinical research on hepatitis delta was presented during a monothematic conference organized by the ...
openaire +2 more sources
AbstractMore than 30 years after Mario Rizzetto and colleagues described a new antigen in livers of HBsAg‐positive patients called the “delta antigen”, a re‐emerging interest in hepatitis delta is currently observed. The state‐of‐the art on basic and clinical research on hepatitis delta was presented during a monothematic conference organized by the ...
openaire +2 more sources
Reviews in Medical Virology, 1998
The hepatitis D virus (HDV) relies on the helper hepatitis B virus (HBV) for the provision of its envelope, which consists of hepatitis B surface antigen (HBsAg). The RNA genome of HDV is a circular rod-like structure due to its extensive intramolecular base-pairing.
openaire +2 more sources
The hepatitis D virus (HDV) relies on the helper hepatitis B virus (HBV) for the provision of its envelope, which consists of hepatitis B surface antigen (HBsAg). The RNA genome of HDV is a circular rod-like structure due to its extensive intramolecular base-pairing.
openaire +2 more sources