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Hepatitis Delta Virus: A Peculiar Virus [PDF]

Advances in Virology, 2013
The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate ...
Carolina Alves, Cristina Branco, Celso Cunha   +2 more
doaj   +3 more sources

Hepatitis Delta Virus Infection: An Overview [PDF]

Pathogens
The burden of hepatitis delta virus (HDV) infection is currently unknown and may affect 12 to 72 million people distributed across various hot spots in different regions of the globe. Screening for antibodies to HDV infection in patients positive for the
Vitor Duque, Diana Duque
doaj   +2 more sources

Infection by Hepatitis Delta Virus [PDF]

Viruses, 2020
Hepatitis delta virus (HDV) and hepatitis B virus (HBV) are blood-borne viruses that infect human hepatocytes and cause significant liver disease. Infections with HBV are more damaging when there is a coinfection with HDV.
John M. Taylor
doaj   +3 more sources

Hepatitis Delta Virus RNA Replication [PDF]

Viruses, 2009
Hepatitis delta virus (HDV) is a distant relative of plant viroids in the animal world. Similar to plant viroids, HDV replicates its circular RNA genome using a double rolling-circle mechanism.
Chung-Hsin Tseng, Michael M. C. Lai
doaj   +3 more sources

Hepatitis Delta Virus–Host Protein Interactions: From Entry to Egress [PDF]

Viruses, 2023
Hepatitis delta virus (HDV) is the smallest known human virus and causes the most severe form of human viral hepatitis, yet it is still not fully understood how the virus replicates and how it interacts with many host proteins during replication.
Susannah Stephenson-Tsoris, T. Jake Liang   +1 more
doaj   +2 more sources

Hepatitis Delta Virus and Hepatocellular Carcinoma [PDF]

Pathogens
The hepatitis D virus (HDV) is a compact, enveloped, circular RNA virus that relies on hepatitis B virus (HBV) envelope proteins to initiate a primary infection in hepatocytes, assemble, and secrete new virions.
Daniele Lombardo, Maria Stella Franzè, Giuseppe Caminiti, Teresa Pollicino   +3 more
doaj   +2 more sources

Hepatitis Delta Virus [PDF]

, 2006
The hepatitis delta virus (HDV) is a subviral agent that utilizes the envelope proteins of the hepatitis B virus (HBV) for cell to cell propagation. In infected human hepatocytes, the HDV RNA genome can replicate and associate with multiple copies of the delta protein to assemble a ribonucleoprotein (RNP).
Hiroshi Handa, Yuki Yamaguchi
  +4 more sources

Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections [PDF]

, 2021
Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer.
Ahlén, G, Frelin, L, Jagya, N, Johansson, M, Maravelia, P, Meuleman, Philip, Ni, Y, Pasetto, A, Pater, L, Pérez, NC, Sällberg, M, Urban, S, Verch, G, Verhoye, Lieven   +13 more
core   +1 more source

Constraint of Base Pairing on HDV Genome Evolution

Viruses, 2021
The hepatitis delta virus is a single-stranded circular RNA virus, which is characterized by high self-complementarity. About 70% of the genome sequences can form base-pairs with internal nucleotides.
Saki Nagata, Ryoji Kiyohara, Hiroyuki Toh   +2 more
doaj   +1 more source

Hepatitis Delta Virus Diagnosis [PDF]

Seminars in Liver Disease, 2012
The first step in the diagnosis of hepatitis delta virus (HDV) infection is testing HBsAg-positive individuals for the antibody to the HD antigen (anti-HD).In anti-HD-positive patients, the next step is testing for HDV RNA in serum to determine whether the antibody reflects an ongoing active HDV infection (HDV-RNA-positive) or represents a serologic ...
OLIVERO, Antonella, SMEDILE, Antonina
openaire   +2 more sources