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Infection by Hepatitis Delta Virus [PDF]
Hepatitis delta virus (HDV) and hepatitis B virus (HBV) are blood-borne viruses that infect human hepatocytes and cause significant liver disease. Infections with HBV are more damaging when there is a coinfection with HDV.
John M. Taylor
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Hepatitis Delta Virus RNA Replication [PDF]
Hepatitis delta virus (HDV) is a distant relative of plant viroids in the animal world. Similar to plant viroids, HDV replicates its circular RNA genome using a double rolling-circle mechanism.
Chung-Hsin Tseng, Michael M. C. Lai
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Hepatitis Delta Virus: A Peculiar Virus [PDF]
The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate ...
Carolina Alves +2 more
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Viroids and Hepatitis Delta Virus
There is a subviral world, whose most prominent representatives are viroids. Despite being solely composed by a circular, highly structured RNA of ~250 to 400 nucleotides without protein-coding ability (all viruses code for one or more proteins), viroids can infect and incite specific diseases in higher plants.
Ricardo Flores +2 more
exaly +4 more sources
Hepatitis Delta Virus (HDV) and Delta-Like Agents: Insights Into Their Origin
Hepatitis delta virus (HDV) is a human pathogen, and the only known species in the genus Deltavirus. HDV is a satellite virus and depends on the hepatitis B virus (HBV) for packaging, release, and transmission.
Hans J. Netter +5 more
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Hepatitis Delta Virus and Hepatocellular Carcinoma
The hepatitis D virus (HDV) is a compact, enveloped, circular RNA virus that relies on hepatitis B virus (HBV) envelope proteins to initiate a primary infection in hepatocytes, assemble, and secrete new virions.
Daniele Lombardo +3 more
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Constraint of Base Pairing on HDV Genome Evolution
The hepatitis delta virus is a single-stranded circular RNA virus, which is characterized by high self-complementarity. About 70% of the genome sequences can form base-pairs with internal nucleotides.
Saki Nagata +2 more
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Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Chronic viral hepatitis D - the current state of a problem. [PDF]
Chronic hepatitis D- severe and rapidly progressing form of viral hepatitis, leading to the liver cirrhosis in 70% of cases within 5-10 years. HDV RNA replicates only in the presence of viral hepatitis B.
Aliya Konysbekova
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