Results 11 to 20 of about 28,924 (184)
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Chronic viral hepatitis D - the current state of a problem. [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2017 Chronic hepatitis D- severe and rapidly progressing form of viral hepatitis, leading to the liver cirrhosis in 70% of cases within 5-10 years. HDV RNA replicates only in the presence of viral hepatitis B.
Aliya Konysbekova
doaj +1 more source
, 2006 The hepatitis delta virus (HDV) is a subviral agent that utilizes the envelope proteins of the hepatitis B virus (HBV) for cell to cell propagation. In infected human hepatocytes, the HDV RNA genome can replicate and associate with multiple copies of the delta protein to assemble a ribonucleoprotein (RNP).
Hiroshi Handa, Yuki Yamaguchi
+4 more sources
JHEP Reports, 2023 Background & Aims: Bulevirtide (BLV) is a small lipopeptide agent that specifically binds to the sodium taurocholate cotransporting polypeptide (NTCP) bile salt transporter and HBV/HDV receptor on the surface of human hepatocytes and inhibits HDV and
Roberto Mateo +21 more
doaj +1 more source
A review on hepatitis D: From virology to new therapies
Journal of Advanced Research, 2019 Hepatitis delta virus (HDV) is a defective virus that requires the hepatitis B virus (HBV) to complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating HBV surface antigen protein and a ribonucleoprotein containing the ...
Nathalie Mentha +3 more
doaj +1 more source
Hepatitis viral en la gestación
Revista Colombiana de Obstetricia y Ginecología, 1996 La primera causa de ictericia en el embarazo es la hepatitis viral que puede ser causada por lo menos por cinco virus (A, B, C, D y E). El descubrimiento del virus de la hepatitis C y Delta prácticamente eliminó las antes denominadas Hepatitis No A No B ...
Pío Iván Gómez Sánchez
doaj +1 more source
Viral Hepatitis Journal, 2018 Objectives:The present study aims to investigate biochemical, virological and histological characteristics of hepatitis delta virus infection, which is a serious problem in our region, as well as its relationship with chronic hepatitis B virus (HBV ...
Mehmet Suat YALÇIN, Kendal YALÇIN
doaj +1 more source
Annals of Hepatology, 2017 Background: Hepatitis delta virus infection occurs as acute coinfection or as superinfection in patients with preexisting chronic hepatitis B. Chronic hepatitis delta leads to more severe disease than chronic hepatitis B, with more rapid progression of ...
Laura Escolà-Vergé +2 more
doaj +1 more source
Recent Advances in Protective Vaccines against Hepatitis Viruses: A Narrative Review
Viruses, 2023 Vaccination has been confirmed to be the safest and, sometimes, the only tool of defense against threats from infectious diseases. The successful history of vaccination is evident in the control of serious viral infections, such as smallpox and polio ...
Ashraf Elbahrawy +7 more
doaj +1 more source