Results 31 to 40 of about 2,037,862 (238)

LIVER TRANSPLANTATION IN HEPATITIS DELTA: SOUTH AMERICA EXPERIENCE

Arquivos de Gastroenterologia
BACKGROUND: The Amazon region is one of the main endemic areas of hepatitis delta in the world and the only one related to the presence of genotype 3 of the delta virus.
Daniel Souza LIMA, Abdon José MURAD JÚNIOR, Márcio Alencar BARREIRA, Guilherme Cardoso FERNANDES, Gustavo Rego COELHO, José Huygens Parente GARCIA   +5 more
doaj   +1 more source

Viroids and Hepatitis Delta Virus

Seminars in Liver Disease, 2012
There is a subviral world, whose most prominent representatives are viroids. Despite being solely composed by a circular, highly structured RNA of ~250 to 400 nucleotides without protein-coding ability (all viruses code for one or more proteins), viroids can infect and incite specific diseases in higher plants.
Flores Pedauye, Ricardo, Ruiz Ruiz, Susana, SERRA ALFONSO, PEDRO   +2 more
openaire   +3 more sources

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source

Hepatite crónica: o espectro etiológico. Implicações para o tratamento.

Acta Médica Portuguesa, 1993
The prevalence of chronic hepatitis and its different aetiologies was studied in all patients above 10 years of age seen in the specialised outpatient clinic of our hospital over a 3 year period.
J Velosa, F Ramalho, F Serejo, R Marinho, M C de Moura   +4 more
doaj   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

The prevalence of occult hepatitis B virus (hbv) infection in a large multi-ethnic haemodialysis cohort. [PDF]

, 2015
Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HBV) infection ...
Labbett, W, Patel, M, O'Riordan, A, Davenport, A, Sowole, L, Haque, T, Cross, J   +6 more
core  

A Rapid Point-of-Care Test for the Serodiagnosis of Hepatitis Delta Virus Infection

Viruses, 2021
Hepatitis Delta virus (HDV) is a satellite of the Hepatitis B virus (HBV) and causes severe liver disease. The estimated prevalence of 15–20 million infected people worldwide may be underestimated as international diagnostic guidelines are not routinely ...
Florian A. Lempp, Imme Roggenbach, Shirin Nkongolo, Volkan Sakin, Franziska Schlund, Paul Schnitzler, Heiner Wedemeyer, Frédéric Le Gal, Emmanuel Gordien, Cihan Yurdaydin, Stephan Urban   +10 more
doaj   +1 more source

Hepatitis Delta Virus and Hepatocellular Carcinoma. [PDF]

Pathogens
The hepatitis D virus (HDV) is a compact, enveloped, circular RNA virus that relies on hepatitis B virus (HBV) envelope proteins to initiate a primary infection in hepatocytes, assemble, and secrete new virions. Globally, HDV infection affects an estimated 12 million to 72 million people, carrying a significantly elevated risk of developing cirrhosis ...
Lombardo D, Franzè MS, Caminiti G, Pollicino T.   +3 more
europepmc   +5 more sources

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Evaluation of Signal/Cut-off Ratio by Anti-hepatitis Delta Virus Enzyme Immunoassay Method in the Diagnosis of Hepatitis Delta Virus Infection

, 2019
Objectives: The hepatitis delta virus (HDV) is an enveloped, negative-sense, single-stranded RNA virus in the genus Deltavirus. In this study, it was aimed to evaluate the ratio of anti-HDV signal/cut-off (S/CO) in the diagnosis of HDV infection in ...
Alaçam, Sema, Bakir, Ayfer, Yaman, Murat, Karabulut, Nuran, Agacfidan, Ali, Onel, Mustafa   +5 more
core   +1 more source