Results 51 to 60 of about 2,037,862 (238)

Eighth Major Clade for Hepatitis Delta Virus

Emerging Infectious Diseases, 2006
Hepatitis delta virus is the only representative of the Deltavirus genus, which consists of 7 differentiated major clades. In this study, an eighth clade was identified from 3 distinct strains.
Frédéric Le Gal, Elyanne Gault, Marie-Pierre Ripault, Jeanne Serpaggi, Jean-Claude Trinchet, Emmanuel Gordien, Paul Dény   +6 more
doaj   +1 more source

Phosphorylation of the hepatitis delta virus antigens [PDF]

Journal of Virology, 1997
We used two-dimensional electrophoresis (nonequilibrium pH gradient electrophoresis followed by sodium dodecyl sulfate-10% polyacrylamide gel electrophoresis) coupled with 32P labeling and immunoblotting detection with 125I-protein A to detect and quantitate phosphorylation of the large and small forms of the delta antigen (deltaAg-L and deltaAg-S ...
V, Bichko, S, Barik, J, Taylor
openaire   +2 more sources

Multiscale Modeling of an 8‐Week Combination Regimen of Bemnifosbuvir and Ruzasvir in Patients with Chronic Hepatitis C Virus Infection

Clinical Pharmacology &Therapeutics, EarlyView.
Bemnifosbuvir (BEM) and ruzasvir (RZR) are pan‐genotypic HCV polymerase (NS5B) and NS5A inhibitors, respectively. In a single‐arm study (NCT05904470), 215 treatment‐naïve, adherent participants with chronic HCV (with or without cirrhosis) received BEM 550 mg QD plus RZR 180 mg QD for 8 weeks.
Carolin Zitzmann, Ruy M. Ribeiro, Aurelien Marc, Xiao‐Jian Zhou, Alan S. Perelson   +4 more
wiley   +1 more source

A practical difference from the normal approach to evaluate natural killer (NK) cells and NK cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk, Afshin Shameli, Erik Ames, Jonathan R. Fromm, Bartosz Grzywacz, Min Shi, Sindhu Cherian, Jean Oak   +7 more
wiley   +1 more source

Antinuclear antibodies (ANA) in chronic hepatitis C virus infection: correlates of positivity and clinical relevance.

, 2004
We examined correlates of antinuclear antibody (ANA) positivity (ANA+) in individuals with chronic hepatitis C virus (HCV) infection and the effect of positivity on clinical outcome of HCV. Pretreatment sera from 645 patients from three centres in Sweden
Marshall, S, Goldin, RD, A. Alberti, A. J. Hall, Yee, LJ, Thomas, HC, Thursz, MR, Chiaramonte, M, Braconier, J-H, Hall, AJ, L. J. Yee, H. C. Thomas, Braconier, Jean Henrik, R. D. Goldin, M. Chiaramonte, M. R. Thursz, S. Marshall, Kelleher, P, Braconier, Jean Henrik,, Alberti, A, Lund University., J.‐H. Braconier, P. Kelleher   +22 more
core   +1 more source

Origin of Hepatitis Delta Virus mRNA [PDF]

Journal of Virology, 2000
ABSTRACT Hepatitis delta virus (HDV) is unique relative to all known animal viruses, especially in terms of its ability to redirect host RNA polymerase(s) to transcribe its 1,679-nucleotide (nt) circular RNA genome. During replication there accumulates not only more molecules of the genome but also its exact complement, the antigenome.
S, Gudima, S Y, Wu, C M, Chiang, G, Moraleda, J, Taylor   +4 more
openaire   +2 more sources

Subset‐specific and tissue‐specific expression of NK‐cell markers and killer immunoglobulin‐like receptors: Implications for NK‐cell clonality assessment

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate immunophenotypic evaluation of natural killer (NK)‐cell neoplasms is challenging because NK‐cells lack somatically rearranged antigen receptors, are comprised of phenotypically distinct subsets, and exhibit tissue‐specific subset distribution. We developed a flow cytometry (FC) panel for NK‐cell immunophenotypic analysis and clonality
Valerie Woodings, Orrin Koepke, Jason E. Love, Alireza Torabi, Lianqun Qiu, Jonathan R. Fromm, Sindhu Cherian, Afshin Shameli   +7 more
wiley   +1 more source

Epidemiology and Genetic Diversity of Hepatitis B Virus and Hepatitis Delta Virus Infection in Indigenous Communities in Colombia

Microorganisms, 2023
Despite the universal vaccination program, there are still regions and territories with a high prevalence of Hepatitis B Virus infection (HBV), such as the Amazon basin, where several indigenous communities live. Additionally, Hepatitis Delta Virus (HDV)
Melissa Montoya-Guzman, Jaime Martinez, Diana Castro-Arroyave, Carlos Rojas, Maria-Cristina Navas   +4 more
doaj   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Nashwa Abousamra, Azza Azza Abdel-Aziz, Mona Elhadidy, Mohamed Abd-elmaksoud, Yahia Gad, Nasser Mousa   +5 more
core  

Diagnosis, management and treatment of hepatitis delta virus infection: Turkey 2017 Clinical Practice Guidelines

The Turkish Journal of Gastroenterology, 2017
Cite this article as: Yurdaydın C, Tabak F, Idilman R; Viral Hepatitis Guidelines Study Group. Diagnosis, management and treatment of hepatitis delta virus infection: Turkey 2017 Clinical Practice Guidelines.
Cihan Yurdaydın, Fehmi Tabak, Sabahattin Kaymakoğlu, Mesut Akarsu, Esra G. Akıncı, Hikmet Akkız, Canan Alkım, Ayhan H. Çekin, Nefise Ö. Çuvalcı, Kadir Demir, Bülent Değertekin, İlyas Dökmetaş, Galip Ersöz, Kenan Hizel, Fatma Ö. Kandemir, Yusuf Önlen, Abdullah Sonsuz, Ebubekir Şenateş, Selma Tosun, Nurdan Tözün, Ramazan Idilman, and Viral Hepatisis Guideline Study Group   +21 more
doaj   +1 more source