Results 71 to 80 of about 28,924 (184)
Objective Sjögren's disease (SjD) is a chronic autoimmune disease with a complex etiology, where pathogens may influence disease development or progression. Although SjD is not communicable, environmental and endemic pathogen exposures may influence its onset or progression.
Swetha K. Shankar +3 more
wiley +1 more source
Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases
Cytochromes P450 (CYPs) and UDP-glucuronosyltransferases (UGTs) are targets of autoantibodies in several hepatic and extrahepatic autoimmune diseases.
Petra Obermayer-Straub +2 more
doaj +1 more source
Bemnifosbuvir: An HCV NS5B Inhibitor With Multiple Modes of Action
Bemnifosbuvir (BEM) is a potent, pan‐genotypic inhibitor targeting the hepatitis C virus (HCV) NS5B polymerase. Its antiviral activity was evaluated in an ascending dose phase I clinical trial involving 30 patients treated once a day for 7 days. After treatment initiation, plasma HCV RNA declined in a biphasic manner with a mean reduction of 2.3 log10 ...
Carolin Zitzmann +4 more
wiley +1 more source
Introduction: Hepatitis D virus (HDV) is a 35 nm in diameter agent that depends on hepatitis B surface antigen in order to proliferate and accumulate. Infection with delta agent can occur spontaneously with hepatitis B virus infection and it cause acute ...
Kh Barkhordari +5 more
doaj
Molecular and Clinical Features of Hepatocellular Carcinoma in Patients with HBV-HDV Infection
Federico Costante,1,* Leonardo Stella,1,* Francesco Santopaolo,1,2 Antonio Gasbarrini,1,2 Maurizio Pompili,1,2 Tarik Asselah,3,* Francesca Romana Ponziani1,2 1Internal Medicine and Gastroenterology - Hepatology Unit, Fondazione Policlinico ...
Costante F +6 more
doaj
Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge +5 more
wiley +1 more source
MOLECULAR EPIDEMIOLOGY FEATURES OF HBV/HDV CO-INFECTION IN KYRGYZSTAN
One of the most serious health problems in the world are hepatotropic viruses that cause chronic liver disease. Hepatitis B virus is distributed globally; around 5% of the carriers are also infected with hepatitis delta virus.
A. V. Semenov +6 more
doaj +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
An Exploratory Cost‐Utility Analysis of Screening and Treating Immigrants in Canada for Hepatitis D
ABSTRACT Hepatitis D is common among immigrants in Canada, who account for approximately 23% of the population and tend to originate from high‐endemic countries. Mortality rates are notably high among those with chronic infections, and immigrants are less likely to engage in screening and treatment services.
Jiahao Zhao +4 more
wiley +1 more source
ABSTRACT Hepatitis delta virus (HDV) infection causes chronic hepatitis D (CHD), the most severe form of chronic viral hepatitis with a high risk of progression to advanced liver disease. Off‐label pegylated interferon alpha was the primary treatment option in Europe prior to the introduction of bulevirtide, a first‐in‐class HDV entry inhibitor.
Monica Radu +11 more
wiley +1 more source

