Results 61 to 70 of about 58,225 (243)

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura, Yuki Murakami, Yusuke Oshima, Takashi Masuda, Wataru Miyoshino, Hiroomi Takayama, Yoko Kawano, Teijiro Hirashita, Yuichi Endo, Masafumi Inomata   +9 more
wiley   +1 more source

Molecular detection of hepatitis delta virus in blood donors with RT-PCR

Medical Laboratory Journal, 2015
Background and Objective: Hepatitis delta virus is an imperfect virus with RNA and its activity depends on the presence of hepatitis B virus. This virus can lead to acute and chronic diseases in the liver.
Malekpour, B., Tajbakhsh, E, Khamesipour, F, Rahimi, A   +3 more
doaj  

Hepatitis Delta Virus (HDV) and Delta-Like Agents: Insights Into Their Origin

Frontiers in Microbiology, 2021
Hepatitis delta virus (HDV) is a human pathogen, and the only known species in the genus Deltavirus. HDV is a satellite virus and depends on the hepatitis B virus (HBV) for packaging, release, and transmission.
Hans J. Netter, Hans J. Netter, Marilou H. Barrios, Marilou H. Barrios, Margaret Littlejohn, Lilly K. W. Yuen   +5 more
doaj   +1 more source

Hepatitis B/C virus co-infection in Iran: A seroepidemiological study [PDF]

, 2007
Background/aims: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.
Abdolahi, N., Besharat, S., Danesh, A., Hosseini, S.A., Jabbari, A., Joshaghani, H., Kabir, M.J., Kalavi, K., Keshtkar, A.A., Moradi, A., Roshandel, D., Roshandel, G., Sedaqat, S.M., Semnani, S.   +13 more
core  

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, EarlyView.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source

The burden of clostridium difficile infection in patients with liver cirrhosis [PDF]

, 2019
Clostridium Difficile Infection (CDI) has registered a dramatically increasing incidence in the general population over the past decades. Nowadays, Clostridium Difficile is the leading cause of hospital-acquired diarrhea in Europe and North America ...
Dumitru, Andrada, Emanuela, Popoiag R, Micu, Sergiu I, Moraru, Despina, Musat, Marilena, Preda, Gabriel   +5 more
core   +2 more sources

Viroids and Hepatitis Delta Virus

Seminars in Liver Disease, 2012
There is a subviral world, whose most prominent representatives are viroids. Despite being solely composed by a circular, highly structured RNA of ~250 to 400 nucleotides without protein-coding ability (all viruses code for one or more proteins), viroids can infect and incite specific diseases in higher plants.
Flores Pedauye, Ricardo, Ruiz Ruiz, Susana, Serra Alfonso, Pedro   +2 more
openaire   +3 more sources

Diagnosis, management and treatment of hepatitis delta virus infection: Turkey 2017 Clinical Practice Guidelines

The Turkish Journal of Gastroenterology, 2017
Cite this article as: Yurdaydın C, Tabak F, Idilman R; Viral Hepatitis Guidelines Study Group. Diagnosis, management and treatment of hepatitis delta virus infection: Turkey 2017 Clinical Practice Guidelines.
Cihan Yurdaydın, Fehmi Tabak, Sabahattin Kaymakoğlu, Mesut Akarsu, Esra G. Akıncı, Hikmet Akkız, Canan Alkım, Ayhan H. Çekin, Nefise Ö. Çuvalcı, Kadir Demir, Bülent Değertekin, İlyas Dökmetaş, Galip Ersöz, Kenan Hizel, Fatma Ö. Kandemir, Yusuf Önlen, Abdullah Sonsuz, Ebubekir Şenateş, Selma Tosun, Nurdan Tözün, Ramazan Idilman, and Viral Hepatisis Guideline Study Group   +21 more
doaj   +1 more source

Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]

, 2015
Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján, Eguibar, Nair, Gonzalez, Rodrigo Horacio, Nusblat, Alejandro David, Perazzo, Priscila   +4 more
core   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source