Results 41 to 50 of about 28,924 (184)

Identification of a novel interaction site between the large hepatitis delta antigen and clathrin that regulates the assembly of genotype III hepatitis delta virus

open access: yesVirology Journal, 2022
Background Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus (HBV), is a small, defective RNA virus strongly associated with the most severe form of hepatitis and progressive chronic liver disease and cirrhosis.
Wei-Chung Chiou   +7 more
doaj   +1 more source

Epidemiology of the Hepatitis D virus

open access: yesWikiJournal of Medicine, 2020
Hepatitis D is a globally occurring liver disease. It afflicts those who have been infected by both the Hepatitis B virus (HBV) and also the Hepatitis D virus (HDV), since HDV needs the hepatitis B surface antigen (HBsAg) to replicate.
Mario Rizzetto
doaj   +1 more source

Ribonucleoprotein complexes of hepatitis delta virus [PDF]

open access: yesJournal of Virology, 1993
Human hepatitis delta virus (HDV) is a subviral satellite agent of hepatitis B virus (HBV). The envelope proteins of HDV are provided by the helper virus, HBV, but very little is known about the internal structure of HDV. The particles contain multiple copies of the delta antigen and an unusual RNA genome that is small, about 1,700 nucleotides in ...
W S, Ryu   +3 more
openaire   +2 more sources

Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen   +4 more
wiley   +1 more source

Molecular detection of hepatitis delta virus in blood donors with RT-PCR

open access: yesMedical Laboratory Journal, 2015
Background and Objective: Hepatitis delta virus is an imperfect virus with RNA and its activity depends on the presence of hepatitis B virus. This virus can lead to acute and chronic diseases in the liver.
Malekpour, B.   +3 more
doaj  

Phosphorylation of the hepatitis delta virus antigens [PDF]

open access: yesJournal of Virology, 1997
We used two-dimensional electrophoresis (nonequilibrium pH gradient electrophoresis followed by sodium dodecyl sulfate-10% polyacrylamide gel electrophoresis) coupled with 32P labeling and immunoblotting detection with 125I-protein A to detect and quantitate phosphorylation of the large and small forms of the delta antigen (deltaAg-L and deltaAg-S ...
V, Bichko, S, Barik, J, Taylor
openaire   +2 more sources

Optimal Control Analysis of Vertically Transmitted Infectious Diseases With Saturated Incidence and Nonlinear Treatment

open access: yesOptimal Control Applications and Methods, EarlyView.
Schematic representation of the proposed disease transmission model incorporating vertical transmission, saturated incidence, and nonlinear treatment. The study combines theoretical analysis, bifurcation and stability investigations, and optimal control techniques to evaluate prevention and treatment interventions.
Oludolapo A. Olanrewaju   +1 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

Origin of Hepatitis Delta Virus mRNA [PDF]

open access: yesJournal of Virology, 2000
ABSTRACT Hepatitis delta virus (HDV) is unique relative to all known animal viruses, especially in terms of its ability to redirect host RNA polymerase(s) to transcribe its 1,679-nucleotide (nt) circular RNA genome. During replication there accumulates not only more molecules of the genome but also its exact complement, the antigenome.
S, Gudima   +4 more
openaire   +2 more sources

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

open access: yesAllergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider   +48 more
wiley   +1 more source

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