Results 1 to 10 of about 1,159,378 (230)
Identification of a novel interaction site between the large hepatitis delta antigen and clathrin that regulates the assembly of genotype III hepatitis delta virus [PDF]
Virology Journal, 2022 Background Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus (HBV), is a small, defective RNA virus strongly associated with the most severe form of hepatitis and progressive chronic liver disease and cirrhosis.
Wei-Chung Chiou +7 more
doaj +2 more sources
Hepatitis Delta Antigen Regulates mRNA and Antigenome RNA Levels During Hepatitis Delta Virus Replication. [PDF]
Journal of Virology, 2019 Yiran Shen, John Louis Casey
exaly +2 more sources
A Rapid Point-of-Care Test for the Serodiagnosis of Hepatitis Delta Virus Infection
Viruses, 2021 Hepatitis Delta virus (HDV) is a satellite of the Hepatitis B virus (HBV) and causes severe liver disease. The estimated prevalence of 15–20 million infected people worldwide may be underestimated as international diagnostic guidelines are not routinely ...
Florian A. Lempp +10 more
doaj +1 more source
Multiple Regions Drive Hepatitis Delta Virus Proliferation and Are Therapeutic Targets
Frontiers in Microbiology, 2022 Hepatitis Delta Virus (HDV) is the smallest mammalian single-stranded RNA virus. It requires host cells and hepatitis B virus (HBV) to complete its unique life cycle.
Jun Zi +5 more
doaj +1 more source
Unexpected findings of hepatitis B and delta infection in northeastern Brazil: A public health alert
Annals of Hepatology, 2021 Introduction and objectives: Research has shown that hepatitis B (HBV) and Delta virus (HDV) are a worldwide public health problem. This study aims to estimate the prevalence rates of HBV and HDV infection in five municipalities of Maranhão, Northeastern
Jomar Diogo Costa Nunes +18 more
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Microbiology Spectrum, 2021 Hepatitis D is the most severe form of human viral hepatitis and currently lacks an efficient therapy. Dendritic cell-derived exosomes (Dexs) have been found to induce immune responses capable of eliminating viruses. However, the therapeutic potential of
Ting Yao +7 more
doaj +1 more source
Constraint of Base Pairing on HDV Genome Evolution
Viruses, 2021 The hepatitis delta virus is a single-stranded circular RNA virus, which is characterized by high self-complementarity. About 70% of the genome sequences can form base-pairs with internal nucleotides.
Saki Nagata +2 more
doaj +1 more source
Virus Research, 2023 RNA editing of the hepatitis delta virus (HDV) is essential for generating the large delta antigen, which is crucial for virion assembly. In HDV genotype 1 (HDV-1), editing occurs within the context of the unbranched rod-like structure characteristic of ...
Chao-Wei Hsu +3 more
doaj +1 more source
A review on hepatitis D: From virology to new therapies
Journal of Advanced Research, 2019 Hepatitis delta virus (HDV) is a defective virus that requires the hepatitis B virus (HBV) to complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating HBV surface antigen protein and a ribonucleoprotein containing the ...
Nathalie Mentha +3 more
doaj +1 more source
Annals of Hepatology, 2017 Background: Hepatitis delta virus infection occurs as acute coinfection or as superinfection in patients with preexisting chronic hepatitis B. Chronic hepatitis delta leads to more severe disease than chronic hepatitis B, with more rapid progression of ...
Laura Escolà-Vergé +2 more
doaj +1 more source