Results 31 to 40 of about 1,159,378 (230)

Structural Pattern Differences in Unbranched Rod-Like RNA of Hepatitis Delta Virus Affect RNA Editing

Viruses, 2019
Hepatitis delta virus (HDV) RNA forms an unbranched rod-like structure and complexes with the delta antigen (HDAg). Host ADAR1-catalyzed RNA editing at the amber/W site of the small HDAg leads to the production of the large HDAg, which inhibits ...
Chao-Wei Hsu, Horng-Heng Juang, Chien-Yi Kuo, Hsin-Pai Li, Shan-Bei Iang, Siao-Han Lin, Chau-Ting Yeh, Mei Chao   +7 more
doaj   +1 more source

Redistribution of the delta antigens in cells replicating the genome of hepatitis delta virus [PDF]

Journal of Virology, 1996
When the small form of the delta antigen (deltaAg-S) was expressed from a cDNA expression plasmid and subsequently detected by immunofluorescence, it was found localized to the nucleoli. However, if the cDNA was cotransfected with a cDNA expressing a mutated hepatitis delta virus (HDV) genome that could only replicate by using the deltaAg-S provided by
V V, Bichko, J M, Taylor
openaire   +2 more sources

Delta hepatitis agent: structural and antigenic properties of the delta-associated particle [PDF]

Infection and Immunity, 1984
Delta agent (delta) was serially passaged to a second and third hepatitis B surface antigen (HBsAg) carrier chimpanzee, using as inoculum the peak delta antigen (delta Ag) serum of an animal previously infected with human serum. The characteristics of serially transmitted delta Ag were similar to those described in first-passage animals.
F, Bonino, B, Hoyer, J W, Shih, M, Rizzetto, R H, Purcell, J L, Gerin   +5 more
openaire   +2 more sources

Hepatitis delta virus genome replication: a polyadenylated mRNA for delta antigen [PDF]

Journal of Virology, 1990
Hepatitis delta virus (HDV) replicates its genome in the nucleus of an infected cell. However, an unsolved problem has been the identification in the cytoplasm of a putative mRNA for the synthesis of the only virus-coded protein, the delta antigen.
S Y, Hsieh, M, Chao, L, Coates, J, Taylor   +3 more
openaire   +2 more sources

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]

, 2012
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga, Raffaele Malinverni, Gerlach, Tilman J., Gerlach, Tilman J, Tilman J Gerlach, Swiss Hepatitis C Cohort Study Group,, Berg, T., Kutalik, Z., Stephanie Bibert, Christian M Lange, Geier, Andreas, Dufour, Jean-François Jacques, Thomas Berg, Malinverni, Raffaele, Regenass, S., Burgisser, Philippe, Regenass, Stephan, Badenhoop, Klaus, Bojunga, Jörg, Lange, Christian M, Dufour, J. F., Stephan Regenass, Gerlach, Tilman Joern, Swiss Hepatitis C Cohort Study Group, Bochud, P. Y., Dufour, Jean-Francois, Bojunga, J., Andreas Geier, Stefan Zeuzem, Negro, F., Cerny, A., Zoltan Kutalik, Lange, Christian, Pierre-Yves Bochud, Sarrazin, C., Tobias Müller, Sarrazin, Christoph, Lange, C. M., Cerny, Andreas, Kutalik, Zoltán, Bibert, S., Malinverni, R., Moradpour, Darius, Christoph Sarrazin, Burgisser, P., Gerlach, T. J., Moradpour, D., Bibert, Stephanie, Klaus Badenhoop, Zeuzem, S., Negro, Francesco, Müller, Tobias, Badenhoop, K., Andreas Cerny, Bochud, Pierre-Yves, Geier, A., Heim, M. H., Muller, T., Francesco Negro, Berg, Thomas, Markus H Heim, Heim, Markus H., Darius Moradpour, Jean-Francois Dufour, Philippe Burgisser, Heim, Markus H, Zeuzem, Stefan, Gerlach, T.J., Heim MH, Geier A, Müller Tobias, Moradpour D, Burgisser Philippe, Malinverni Raffaele, Badenhoop K, Bochud Pierre-Yves, Regenass Stephan, Dufour Jean-Francois, Regenass S, Dufour JF, Negro Francesco, Cerny A, Zeuzem Stefan, Bochud, P.Y., Dufour, J.F., Heim Markus H., Berg Thomas, Geier Andreas, Berg T, Sarrazin Christoph, Burgisser P, Malinverni R, Badenhoop Klaus, Bojunga Jörg, Zeuzem S, Bochud PY, Cerny Andreas, Sarrazin C, Bibert Stephanie, Moradpour Darius, Bibert S, Lange CM, Kutalik Z, Kutalik Zoltan, Lange Christian M., Lange, C.M., Gerlach Tilman J., Heim, M.H., Gerlach TJ, Negro F, Müller T, Bojunga J   +111 more
core   +2 more sources

Evolutionary trends in the prevalence of anti-HDV antibodies among patients positive for HBsAg referred to a national laboratory in Cameroon from 2012 to 2017

BMC Research Notes, 2019
Objective The aim of this study was to update the data on the prevalence of anti-HDV antibodies in Cameroon. Results Antibodies against hepatitis Delta virus (Anti-HDV) were found in 16.48% (95% CI 11.46–18.77%) of 426 hepatitis B virus surface antigen ...
Laurence Noubissi-Jouegouo, Marie Amougou Atsama, Paul Alain Tagnouokam-Ngoupo, Chavely Gwladys Monamele, Laure Ngono, Richard Njouom   +5 more
doaj   +1 more source

Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens [PDF]

Journal of Virology, 1994
Hepatitis delta virus (HDV) is composed of four specific components. The first component is envelope protein which contains hepatitis B surface antigens. The second and third components are nucleocapsid proteins, referred to as small and large hepatitis delta antigens (HDAgs).
H W, Wang, P J, Chen, C Z, Lee, H L, Wu, D S, Chen   +4 more
openaire   +2 more sources

Characterization of hepatitis B and delta coinfection in Israel

BMC Infectious Diseases, 2018
Background Characteristics of hepatitis B (HBV) and delta (HDV) coinfection in various geographical regions, including Israel, remain unclear. Here we studied HDV seroprevalence in Israel, assessed HDV/HBV viral loads, circulating genotypes and hepatitis
Rachel Shirazi, Daniela Ram, Aviya Rakovsky, Efrat Bucris, Yael Gozlan, Yaniv Lustig, Pninit Shaked-Mishan, Orit Picard, Yonat Shemer-Avni, Haim Ben-Zvi, Ora Halutz, Yoav Lurie, Ella Veizman, Matthias Carlebach, Marius Braun, Michal Cohen- Naftaly, Amir Shlomai, Rifaat Safadi, Ella Mendelson, Ella H. Sklan, Ziv Ben-Ari, Orna Mor   +21 more
doaj   +1 more source

Epidemiology of hepatitis B virus infection among preconception couples in South China: a cross-sectional study

BMJ Open, 2023
Objectives Hepatitis B virus (HBV) infection is a global public health threat, and couples of reproductive age comprise a key population in aiming to reduce both the vertical and horizontal transmission of HBV.
Qingguo Zhao, Zhijiang Liang, Jialing Qiu, Qianqian Xiang, Jing Yi, Juan Zhu   +5 more
doaj   +1 more source

Evidence of an Exponential Decay Pattern of the Hepatitis Delta Virus Evolution Rate and Fluctuations in Quasispecies Complexity in Long-Term Studies of Chronic Delta Infection. [PDF]

PLoS ONE, 2016
Chronic HDV infection can cause a severe form of viral hepatitis for which there is no specific treatment. Characterization of the hepatitis B or C viral quasispecies has provided insight into treatment failure and disease recurrence following liver ...
Maria Homs, Francisco Rodriguez-Frias, Josep Gregori, Alicia Ruiz, Pilar Reimundo, Rosario Casillas, David Tabernero, Cristina Godoy, Salma Barakat, Josep Quer, Mar Riveiro-Barciela, Michael Roggendorf, Rafael Esteban, Maria Buti   +13 more
doaj   +1 more source