Results 41 to 50 of about 1,159,378 (230)

Positive Selection of Hepatitis Delta Antigen in Chronic Hepatitis D Patients [PDF]

Journal of Virology, 2007
ABSTRACTLiver disease may become ameliorated in some patients with chronic hepatitis D virus (HDV) infection. We present here a study based on longitudinal sampling to investigate the viral dynamics in chronic HDV infection. We examined the HDV variants from different time points, especially those before and after the elevation of serum ...
Shen-Yung, Wang, Jaw-Ching, Wu, Tzen-Yuh, Chiang, Yi-Hsiang, Huang, Chien-Wei, Su, I-Jane, Sheen   +5 more
openaire   +2 more sources

Hepatitis Delta Virus Antigens Trigger Oxidative Stress, Activate Antioxidant Nrf2/ARE Pathway, and Induce Unfolded Protein Response

Antioxidants, 2023
Hepatitis delta virus (HDV) is a viroid-like satellite that may co-infect individuals together with hepatitis B virus (HBV), as well as cause superinfection by infecting patients with chronic hepatitis B (CHB).
Olga A. Smirnova, Olga N. Ivanova, Furkat Mukhtarov, Vladimir T. Valuev-Elliston, Artemy P. Fedulov, Petr M. Rubtsov, Natalia F. Zakirova, Sergey N. Kochetkov, Birke Bartosch, Alexander V. Ivanov   +9 more
doaj   +1 more source

Cellular Factors Involved in the Hepatitis D Virus Life Cycle

Viruses, 2023
Hepatitis D virus (HDV) is a defective RNA virus with a negative-strand RNA genome encompassing less than 1700 nucleotides. The HDV genome encodes only for one protein, the hepatitis delta antigen (HDAg), which exists in two forms acting as ...
Keerthihan Thiyagarajah, Michael Basic, Eberhard Hildt   +2 more
doaj   +1 more source

Relating structure to function in the hepatitis delta virus antigen [PDF]

Journal of Virology, 1993
Hepatitis delta virus expresses two forms of a single protein, the small (delta Ag-S) and large (delta Ag-L) antigens, which are identical except for an additional 19 residues present at the C terminus of delta Ag-L. While delta Ag-S is required to promote genome replication, delta Ag-L potently inhibits this process and also facilitates packaging of ...
D W, Lazinski, J M, Taylor
openaire   +2 more sources

PreHevbrio: the first approved 3-antigen hepatitis B vaccine

Expert Review of Vaccines, 2023
Introduction Hepatitis B remains a major cause of death and morbidity worldwide. Universal childhood immunization programs have been very successful, but many adults remain unprotected or are not optimally protected.
Timo Vesikari, Joanne M Langley, Vlad Popovic, Francisco Diaz-Mitoma   +3 more
doaj   +1 more source

Variable In Vivo Hepatitis D Virus (HDV) RNA Editing Rates According to the HDV Genotype

Viruses, 2021
Human hepatitis delta virus (HDV) is a small defective RNA satellite virus that requires hepatitis B virus (HBV) envelope proteins to form its own virions.
Samira Dziri, Christophe Rodriguez, Athenaïs Gerber, Ségolène Brichler, Chakib Alloui, Dominique Roulot, Paul Dény, Jean Michel Pawlotsky, Emmanuel Gordien, Frédéric Le Gal   +9 more
doaj   +1 more source

Signature of chronic hepatitis B virus infection in nails and hair

BMC Infectious Diseases, 2022
Background Hepatitis B virus (HBV) is detected in extrahepatic tissues of individuals with HBV infection. Whether nails and hair contain HBV has been unknown.
Haruki Komatsu, Ayano Inui, Enkhtaivan Odmaa, Yoshinori Ito, Hiroki Hoshino, Shuichiro Umetsu, Tomoyuki Tsunoda, Tomoo Fujisawa   +7 more
doaj   +1 more source

Distinct histological patterns in chronic hepatitis D with nucleos(t)ide analogue therapy

Frontiers in Medicine, 2023
BackgroundChronic hepatitis delta virus (HDV) infection leads to a more severe hepatitis than hepatitis B virus (HBV) infection alone. Specific histological staining patterns have been described in HBV mono-infection, however this has not been ...
Julian Hercun, Theo Heller, Jeffrey S. Glenn, David E. Kleiner, Christopher Koh   +4 more
doaj   +1 more source

Phylogenetic analysis of HDV isolates from HBsAg positive patients in Karachi, Pakistan

Virology Journal, 2012
Background In spite of a high occurrence of Hepatitis Delta in the province of Sindh in Pakistan, no genetic study of Hepatitis Delta virus (HDV) isolates from this region was carried out.
Perveen Shadab, Nasir Muhammad, Shahid Syed M, Azhar Abid, Khan Obaid   +4 more
doaj   +1 more source

High prevalence of hepatitis delta virus among people with hepatitis B virus and HIV coinfection in Botswana

Journal of Infection and Public Health, 2023
Background: Approximately 15–20 million people worldwide are infected with hepatitis delta virus (HDV), which is approximately 5 % of people with chronic hepatitis B virus (HBV).
Kabo Baruti, Bonolo B. Phinius, Basetsana Phakedi, Gorata Mpebe, Wonderful Choga, Lynnette Bhebhe, Graceful Mulenga, Natasha O. Moraka, Tsholofelo Ratsoma, Molly Pretorius-Holme, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Mosimanegape Jongman, Motswedi Anderson, Simani Gaseitsiwe   +16 more
doaj   +1 more source