Results 91 to 100 of about 2,037,862 (238)

Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus.

open access: yesPLoS ONE, 2010
Hepatitis B virus (HBV) and hepatitis delta virus (HDV) are major sources of acute and chronic hepatitis. HDV requires the envelope proteins of HBV for the processes of assembly and infection of new cells.
John M Taylor, Ziying Han
doaj   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

open access: yesThe FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini   +4 more
wiley   +1 more source

Prevalence of hepatitis delta virus among hemodialysis and renal transplant patients

open access: yes, 2018
Introduction: Hepatitis B virus infection is an important cause of liver disease in hemodialysis patients and renal transplant recipients. Hepatitis Delta virus is a defective virus transmitted by the same route of hepatitis B virus, which requires the ...
Emori, Christini Takemi [UNIFESP]   +19 more
core   +1 more source

COINFECTION BY HEPATITIS B AND HEPATITIS DELTA VIRUSES: MOLECULAR BIOLOGY OF PATHOGENS AND PROSPECTS OF PHARMACOTHERAPY

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Hepatitis delta virus (HDV) is a defective virus and obligate companion of hepatitis B virus (HBV). The clinical significance of HDV and HBV coinfection is associated with more severe forms of acute or chronic viral hepatitis, a higher risk of developing
I. P. Balmasova   +4 more
doaj   +1 more source

Early On‐Treatment Change in SALT as a Pragmatic Predictor of Ritlecitinib Response in Moderate‐To‐Severe Alopecia Areata: A Real‐World Cohort Study

open access: yesInternational Journal of Dermatology, EarlyView.
Ritlecitinib induced rapid clinical improvement in moderate‐to‐severe alopecia areata in real‐world practice. Early change in SALT at Week 12 strongly discriminated Week‐24 responders, supporting a pragmatic treat‐to‐target checkpoint, alongside improvements in clinician‐reported and patient‐reported outcomes and a favorable safety profile.
Giuseppe Gallo   +4 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, Volume 138, Issue 45, 2 November 2026.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Association of Aspirin With Improved Clinical Outcomes and Survival in Patients With Compensated Cirrhosis: A Propensity Score‐Matched Study of 25 782 Individuals

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Pharmacologic therapies to prevent decompensation in cirrhosis remain limited. Aim To evaluate the association between aspirin use and cirrhosis‐related outcomes and mortality. Methods This retrospective cohort study utilized deidentified electronic health records from a global federated network (January 2013–July 2025). Adults with
Shahem Abbarh   +6 more
wiley   +1 more source

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

open access: yes, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm   +25 more
core   +2 more sources

Histone H1e Interacts with Small Hepatitis Delta Antigen and Affects Hepatitis Delta Virus Replication

open access: yes, 2011
Hepatitis delta virus (HDV) encodes two isoforms of delta antigens (HDAgs ). The small form of HDAg (SHDAg) is required for HDV RNA replication, while the large form of HDAg ( LHDAg) is required for viral assembly.
李嘉哲;許金川   +1 more
core   +1 more source

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection [PDF]

open access: yes, 2010
NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill ...
Richard J. Gilson   +50 more
core   +1 more source

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