Results 1 to 10 of about 9,170 (135)

Hepatitis Delta Virus Antigens Trigger Oxidative Stress, Activate Antioxidant Nrf2/ARE Pathway, and Induce Unfolded Protein Response

Antioxidants, 2023
Hepatitis delta virus (HDV) is a viroid-like satellite that may co-infect individuals together with hepatitis B virus (HBV), as well as cause superinfection by infecting patients with chronic hepatitis B (CHB).
Olga A. Smirnova, Olga N. Ivanova, Furkat Mukhtarov, Vladimir T. Valuev-Elliston, Artemy P. Fedulov, Petr M. Rubtsov, Natalia F. Zakirova, Sergey N. Kochetkov, Birke Bartosch, Alexander V. Ivanov   +9 more
doaj   +3 more sources

Proteins and peptides as antigen candidates for the immunodiagnosis of hepatitis D [PDF]

Amino Acids
Designing innovative, accurate, universal, and accessible diagnostic tests is mandatory to improve screening, prevention, and management of hepatitis D (HD), especially in endemic areas with poor infrastructure and restricted access to public health care.
Sandra Rodrigues Xavier, Isabelle Caroline dos Santos Barcelos, Isadora Braga Gandra, Sabrina Paula Pereira, Anna Julia Ribeiro, Kamila Alves Silva, Carlos Ananias Aparecido Resende, Lucas da Silva Lopes, Rafaela Camargo Rodrigues Machado, Leonardo Maciel Santos Silva, Líria Souza Silva, Lívia Corrêa Ferreira, Luiz Fellype Alves de Souza, Rutilene Barbosa Souza, Ana Maísa Passos-Silva, Mariana Campos da Paz, Miguel Angel Chávez Fumagalli, Eduardo Antônio Ferraz Coelho, Rodolfo Cordeiro Giunchetti, Juliana Martins Machado, Ana Alice Maia Gonçalves, Soraya dos Santos Pereira, Daniel Archimedes da Matta, Deusilene Souza Vieira, Alexsandro Sobreira Galdino   +24 more
doaj   +2 more sources

Evidence of an Exponential Decay Pattern of the Hepatitis Delta Virus Evolution Rate and Fluctuations in Quasispecies Complexity in Long-Term Studies of Chronic Delta Infection. [PDF]

PLoS ONE, 2016
Chronic HDV infection can cause a severe form of viral hepatitis for which there is no specific treatment. Characterization of the hepatitis B or C viral quasispecies has provided insight into treatment failure and disease recurrence following liver ...
Maria Homs, Francisco Rodriguez-Frias, Josep Gregori, Alicia Ruiz, Pilar Reimundo, Rosario Casillas, David Tabernero, Cristina Godoy, Salma Barakat, Josep Quer, Mar Riveiro-Barciela, Michael Roggendorf, Rafael Esteban, Maria Buti   +13 more
doaj   +3 more sources

Interaction of Host Cellular Proteins with Components of the Hepatitis Delta Virus

Viruses, 2010
The hepatitis delta virus (HDV) is the smallest known RNA pathogen capable of propagation in the human host and causes substantial global morbidity and mortality.
Valerie Greco-Stewart, Martin Pelchat
doaj   +3 more sources

Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens [PDF]

Journal of Virology, 1994
Hepatitis delta virus (HDV) is composed of four specific components. The first component is envelope protein which contains hepatitis B surface antigens. The second and third components are nucleocapsid proteins, referred to as small and large hepatitis delta antigens (HDAgs).
H W Wang, H L Wu, D S Chen
exaly   +3 more sources

Predominance of HBV Genotype B and HDV Genotype 1 in Vietnamese Patients with Chronic Hepatitis

Viruses, 2021
Hepatitis delta virus (HDV) coinfection will additionally aggravate the hepatitis B virus (HBV) burden in the coming decades, with an increase in HBV-related liver diseases.
Nghiem Xuan Hoan, Mirjam Hoechel, Alexandru Tomazatos, Chu Xuan Anh, Srinivas Reddy Pallerla, Le Thi Kieu Linh, Mai Thanh Binh, Bui Tien Sy, Nguyen Linh Toan, Heiner Wedemeyer, C.-Thomas Bock, Peter G. Kremsner, Christian G. Meyer, Le Huu Song, Thirumalaisamy P. Velavan   +14 more
doaj   +1 more source

Hepatitis Delta Virus (HDV) and Delta-Like Agents: Insights Into Their Origin

Frontiers in Microbiology, 2021
Hepatitis delta virus (HDV) is a human pathogen, and the only known species in the genus Deltavirus. HDV is a satellite virus and depends on the hepatitis B virus (HBV) for packaging, release, and transmission.
Hans J. Netter, Hans J. Netter, Marilou H. Barrios, Marilou H. Barrios, Margaret Littlejohn, Lilly K. W. Yuen   +5 more
doaj   +1 more source

Phosphorylation of the hepatitis delta virus antigens [PDF]

Journal of Virology, 1997
We used two-dimensional electrophoresis (nonequilibrium pH gradient electrophoresis followed by sodium dodecyl sulfate-10% polyacrylamide gel electrophoresis) coupled with 32P labeling and immunoblotting detection with 125I-protein A to detect and quantitate phosphorylation of the large and small forms of the delta antigen (deltaAg-L and deltaAg-S ...
V, Bichko, S, Barik, J, Taylor
openaire   +2 more sources

A novel form of hepatitis delta antigen [PDF]

Journal of Virology, 1996
Hepatitis delta virus (HDV) is known to express a protein termed the small delta antigen, a structural protein which is also essential for genome replication. During replication, posttranscriptional RNA editing specifically modifies some of the HDV RNA, leading to the production of an elongated form of the delta antigen, the large form, which is ...
V V, Bichko, Y E, Khudyakov, J M, Taylor
openaire   +2 more sources

Ubiquitinated Hepatitis D Antigen-Loaded Microvesicles Induce a Potent Specific Cellular Immune Response to Inhibit HDV Replication in Vivo

Microbiology Spectrum, 2021
Hepatitis D is the most severe form of human viral hepatitis and currently lacks an efficient therapy. Dendritic cell-derived exosomes (Dexs) have been found to induce immune responses capable of eliminating viruses. However, the therapeutic potential of
Ting Yao, Mengjiao Lv, Siyuan Ma, Jinmei Chen, Yi Zhang, Yongsheng Yu, Guoqing Zang, Xiaohua Chen   +7 more
doaj   +1 more source