Results 31 to 40 of about 823,470 (204)

Hepatitis delta virus genome replication: a polyadenylated mRNA for delta antigen [PDF]

Journal of Virology, 1990
Hepatitis delta virus (HDV) replicates its genome in the nucleus of an infected cell. However, an unsolved problem has been the identification in the cytoplasm of a putative mRNA for the synthesis of the only virus-coded protein, the delta antigen.
S Y, Hsieh, M, Chao, L, Coates, J, Taylor   +3 more
openaire   +2 more sources

Mutations in SRD5B1 (AKR1D1), the gene encoding Delta(4)-3-oxosteroid 5 beta-reductase, in hepatitis and liver failure in infancy [PDF]

, 2003
Background: A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids, the glycine and taurine conjugates of 7alpha-hydroxy-3-oxo-4-cholenoic acid and 7alpha, 12alpha-dihydroxy-3- oxo-4-cholenoic ...
Duran, M., Scambler, PJ, Custard, E. J., Bouquet, J, Lemonde, H. A., Clayton, P. T., Duran, M, Overmars, H, Bouquet, J., Scambler, P.J., Lemonde, H., Clayton, P.T., Custard, EJ, Scambler, P. J., Clayton, PT, Lemonde, HA, Custard, E.J., Overmars, H.   +17 more
core   +2 more sources

Delta hepatitis agent: structural and antigenic properties of the delta-associated particle [PDF]

Infection and Immunity, 1984
Delta agent (delta) was serially passaged to a second and third hepatitis B surface antigen (HBsAg) carrier chimpanzee, using as inoculum the peak delta antigen (delta Ag) serum of an animal previously infected with human serum. The characteristics of serially transmitted delta Ag were similar to those described in first-passage animals.
F, Bonino, B, Hoyer, J W, Shih, M, Rizzetto, R H, Purcell, J L, Gerin   +5 more
openaire   +2 more sources

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin, Sanford, Brenton J, Kenney, Scott P, Dryman, Barbara A, Córdoba, Laura, Opriessnig, Tanja   +5 more
core   +1 more source

Hepatitis Delta Virus among Hepatitis B Virus-Infected Patients in Jordan: Where Do We Stand? [PDF]

Journal of Bioscience and Applied Research, 2017
Infection by Hepatitis Delta Virus (HDV) which can only replicate in the presence of Hepatitis B Virus (HBV) is a cause of significant morbidity and mortality worldwide. The prevalence of HDV in Jordan is lacking.
doaj   +1 more source

Positive Selection of Hepatitis Delta Antigen in Chronic Hepatitis D Patients [PDF]

Journal of Virology, 2007
ABSTRACTLiver disease may become ameliorated in some patients with chronic hepatitis D virus (HDV) infection. We present here a study based on longitudinal sampling to investigate the viral dynamics in chronic HDV infection. We examined the HDV variants from different time points, especially those before and after the elevation of serum ...
Shen-Yung, Wang, Jaw-Ching, Wu, Tzen-Yuh, Chiang, Yi-Hsiang, Huang, Chien-Wei, Su, I-Jane, Sheen   +5 more
openaire   +2 more sources

Immunological aspects of persistent hepatitis B in children [PDF]

, 2001
We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality.
Notoatmojo, Harsoyo
core   +1 more source

Unique Properties of the Large Antigen of Hepatitis Delta Virus [PDF]

Journal of Virology, 1999
ABSTRACT The large form of the hepatitis delta virus (HDV) protein (L) can be isoprenylated near its C terminus, and this modification is considered essential for particle assembly. Using gel electrophoresis, we separated L into two species of similar mobilities. The slower species could be labeled by the incorporation of [
G, Moraleda, S, Seeholzer, V, Bichko, R, Dunbrack, J, Otto, J, Taylor   +5 more
openaire   +2 more sources

Epidemiology of Occult Hepatitis B Infection Among Thalassemic, Hemophilia, and Hemodialysis Patients [PDF]

, 2012
Context: Hepatitis B virus (HBV) is the most common disease commuted through blood transfusion. Occult hepatitis B infection (OBI) is a form of the disease which does not present Hepatitis B surface antigens (HBsAg) in the serum of patients; however ...
Ahmadabadi, Behzad Nasiri, Kennedy, Derek, Derek Kennedy, Behzad Nasiri Ahmadabadi, Mohammad Kazemi Arababadi, Arababadi, Mohammad Kazemi, Hassan Yousefi Daredor, Daredor, Hassan Yousefi   +7 more
core   +1 more source

Removal of the C6 Vaccinia Virus Interferon-β Inhibitor in the Hepatitis C Vaccine Candidate MVA-HCV Elicited in Mice High Immunogenicity in Spite of Reduced Host Gene Expression

Viruses, 2018
Hepatitis C virus (HCV) represents a major global health problem for which a vaccine is not available. Modified vaccinia virus Ankara (MVA)-HCV is a unique HCV vaccine candidate based in the modified vaccinia virus Ankara (MVA) vector expressing the ...
María Q. Marín, Patricia Pérez, Carmen E. Gómez, Carlos Óscar S. Sorzano, Mariano Esteban, Juan García-Arriaza   +5 more
doaj   +1 more source