Results 21 to 30 of about 823,470 (204)

Genotype-Specific Complementation of Hepatitis Delta Virus RNA Replication by Hepatitis Delta Antigen [PDF]

Journal of Virology, 1998
ABSTRACT Characterizations of genetic variations among hepatitis delta virus (HDV) isolates have focused principally on phylogenetic analysis of sequences, which vary by 30 to 40% among three genotypes and about 10 to 15% among isolates of the same genotype.
J L, Casey, J L, Gerin
openaire   +2 more sources

Clinical and virological heterogeneity of hepatitis delta in different regions world‐wide: The Hepatitis Delta International Network (HDIN)

, 2017
Background & Aims: Chronic hepatitis D (delta) is a major global health burden. Clinical and virological characteristics of patients with hepatitis D virus (HDV) infection and treatment approaches in different regions world-wide are poorly defined ...
Michael P. Manns, Heiner Wedemeyer, Svenja Hardtke, Niro, Grazia A., Peter Ferenci, Naranjargal Dashdorj, Anika Wranke, Markus Cornberg, Maria Buti, Lobato, Cirley, Rizzetto, Mario, Adriana Motoc, Zaigham Abbas, Ceausu, Emanoil, Wranke, Anika, Ferenci, Peter, Vanwolleghem, Thomas, George N. Dalekos, Grazia A. Niro, Yurdaydin, Cihan, Tonya Hayden, Lubna, Farheen, Mario Rizzetto, Parana, Raymundo, Pinheiro Borzacov, Lourdes M., null null, Thomas Vanwolleghem, Emanoil Ceausu, Abbas, Minaam, Raymundo Parana, Minaam Abbas, Cihan Yurdaydin, Buti, Maria, Ingiliz, Patrick, Lourdes M. Pinheiro Borzacov, Borzacov, Lourdes M. Pinheiro, Dalekos, George N., Patrick Ingiliz, Farheen Lubna, Hardtke, Svenja, Wedemeyer, Heiner, Cirley Lobato, Hamid, Saeed, Turcanu, Adela, Hayden, Tonya, Motoc, Adriana, Dashdorj, Naranjargal, Adela Turcanu, Cornberg, Markus, Saeed Hamid, Manns, Michael P., Abbas, Zaigham   +51 more
core   +2 more sources

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection [PDF]

, 2002
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in
Ogg, GS, Antonio Bertoletti, Brown, D., Dusheiko, G., Brown, D, Geoff Dusheiko, Williams, R., George J.M. Webster, Webster, GJ, Seneviratne, SL, Webster, G.J.M., Reignat, S, David Brown, Mala K. Maini, Stephanie Reignat, King, A., Dusheiko, G, Maini, MK, Bertoletti, A, Suranjith L. Seneviratne, Roger Williams, King, A, Bertoletti, A., Reignat, S., Williams, R, Maini, M.K., Graham S. Ogg, Abigail King, Ogg, G.S., Seneviratne, S.L.   +29 more
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Hepatitis Delta Virus: A Peculiar Virus

Advances in Virology, 2013
The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate ...
Carolina Alves, Cristina Branco, Celso Cunha   +2 more
doaj   +1 more source

The large form of hepatitis delta antigen is crucial for assembly of hepatitis delta virus. [PDF]

Proceedings of the National Academy of Sciences, 1991
The virions of hepatitis delta virus (HDV) contain two species of HDV-specific protein, a large and a small form of hepatitis delta antigen (HDAg). We examined the role of individual HDAgs in virion assembly in cotransfection experiments. First, we constructed a replication-competent HDV mutant expressing only the small HDAg.
F L, Chang, P J, Chen, S J, Tu, C J, Wang, D S, Chen   +4 more
openaire   +2 more sources

Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing [PDF]

, 1988
Krämer A, Herth D, von Keyserlingk H, et al. Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing. Klinische Wochenschrift.
Sommer, D., Ludwig, W. D., Hampl, Hartmut, Riecken, Ernst-Otto, Krämer, Alexander ; https://orcid.org/, Hahn, E. G., von Keyserlingk, H., Herth, D.   +7 more
core   +1 more source

Seroprevalence of viral hepatitis in riverine communities from the Western Region of the Brazilian Amazon Basin

Memorias do Instituto Oswaldo Cruz, 2001
The western region of the Brazilian Amazon Basin has long been shown to be a highly endemic area for hepatitis B and hepatitis D viruses. Data concerning the prevalence of hepatitis C and E viruses in this region are still scarce.
VS de Paula, ME Arruda, CL Vitral, AMC Gaspar   +3 more
doaj   +1 more source

Redistribution of the delta antigens in cells replicating the genome of hepatitis delta virus [PDF]

Journal of Virology, 1996
When the small form of the delta antigen (deltaAg-S) was expressed from a cDNA expression plasmid and subsequently detected by immunofluorescence, it was found localized to the nucleoli. However, if the cDNA was cotransfected with a cDNA expressing a mutated hepatitis delta virus (HDV) genome that could only replicate by using the deltaAg-S provided by
V V, Bichko, J M, Taylor
openaire   +2 more sources

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]

, 2005
CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J, Ornella Franzese, Antonio Bertoletti, Maini, Mk, Franzese, O., Williams, R., Adam J. Gehring, Gehring, A.J., Roger Williams, Gehring, Aj, Gotto, J., Bertoletti, A., Kennedy, P.T.F., Williams, R, Maini, M.K., Patrick T. F. Kennedy, Kennedy, Ptf, Jim Gotto, Mala K. Maini, FRANZESE, ORNELLA   +19 more
core   +1 more source

The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen

Virology Journal, 2011
Background Hepatitis delta virus (HDV) is considered to be a satellite virus of the Hepatitis B virus. The genome consists of a 1679 nt ssRNA molecule in which a single ORF was identified.
Cunha Celso, da Cruz e Silva Edgar, Fardilha Margarida, Casaca Ana   +3 more
doaj   +1 more source