Results 21 to 30 of about 9,189 (154)

Hepatitis Delta Virus: A Peculiar Virus

Advances in Virology, 2013
The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate ...
Carolina Alves, Cristina Branco, Celso Cunha   +2 more
doaj   +1 more source

The large form of hepatitis delta antigen is crucial for assembly of hepatitis delta virus. [PDF]

Proceedings of the National Academy of Sciences, 1991
The virions of hepatitis delta virus (HDV) contain two species of HDV-specific protein, a large and a small form of hepatitis delta antigen (HDAg). We examined the role of individual HDAgs in virion assembly in cotransfection experiments. First, we constructed a replication-competent HDV mutant expressing only the small HDAg.
F L, Chang, P J, Chen, S J, Tu, C J, Wang, D S, Chen   +4 more
openaire   +2 more sources

Seroprevalence of viral hepatitis in riverine communities from the Western Region of the Brazilian Amazon Basin

Memorias do Instituto Oswaldo Cruz, 2001
The western region of the Brazilian Amazon Basin has long been shown to be a highly endemic area for hepatitis B and hepatitis D viruses. Data concerning the prevalence of hepatitis C and E viruses in this region are still scarce.
VS de Paula, ME Arruda, CL Vitral, AMC Gaspar   +3 more
doaj   +1 more source

Redistribution of the delta antigens in cells replicating the genome of hepatitis delta virus [PDF]

Journal of Virology, 1996
When the small form of the delta antigen (deltaAg-S) was expressed from a cDNA expression plasmid and subsequently detected by immunofluorescence, it was found localized to the nucleoli. However, if the cDNA was cotransfected with a cDNA expressing a mutated hepatitis delta virus (HDV) genome that could only replicate by using the deltaAg-S provided by
V V, Bichko, J M, Taylor
openaire   +2 more sources

The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen

Virology Journal, 2011
Background Hepatitis delta virus (HDV) is considered to be a satellite virus of the Hepatitis B virus. The genome consists of a 1679 nt ssRNA molecule in which a single ORF was identified.
Cunha Celso, da Cruz e Silva Edgar, Fardilha Margarida, Casaca Ana   +3 more
doaj   +1 more source

Delta hepatitis agent: structural and antigenic properties of the delta-associated particle [PDF]

Infection and Immunity, 1984
Delta agent (delta) was serially passaged to a second and third hepatitis B surface antigen (HBsAg) carrier chimpanzee, using as inoculum the peak delta antigen (delta Ag) serum of an animal previously infected with human serum. The characteristics of serially transmitted delta Ag were similar to those described in first-passage animals.
F, Bonino, B, Hoyer, J W, Shih, M, Rizzetto, R H, Purcell, J L, Gerin   +5 more
openaire   +2 more sources

Hepatitis delta virus genome replication: a polyadenylated mRNA for delta antigen [PDF]

Journal of Virology, 1990
Hepatitis delta virus (HDV) replicates its genome in the nucleus of an infected cell. However, an unsolved problem has been the identification in the cytoplasm of a putative mRNA for the synthesis of the only virus-coded protein, the delta antigen.
S Y, Hsieh, M, Chao, L, Coates, J, Taylor   +3 more
openaire   +2 more sources

Hepatitis Delta Virus among Hepatitis B Virus-Infected Patients in Jordan: Where Do We Stand? [PDF]

Journal of Bioscience and Applied Research, 2017
Infection by Hepatitis Delta Virus (HDV) which can only replicate in the presence of Hepatitis B Virus (HBV) is a cause of significant morbidity and mortality worldwide. The prevalence of HDV in Jordan is lacking.
doaj   +1 more source

Positive Selection of Hepatitis Delta Antigen in Chronic Hepatitis D Patients [PDF]

Journal of Virology, 2007
ABSTRACTLiver disease may become ameliorated in some patients with chronic hepatitis D virus (HDV) infection. We present here a study based on longitudinal sampling to investigate the viral dynamics in chronic HDV infection. We examined the HDV variants from different time points, especially those before and after the elevation of serum ...
Shen-Yung, Wang, Jaw-Ching, Wu, Tzen-Yuh, Chiang, Yi-Hsiang, Huang, Chien-Wei, Su, I-Jane, Sheen   +5 more
openaire   +2 more sources

Removal of the C6 Vaccinia Virus Interferon-β Inhibitor in the Hepatitis C Vaccine Candidate MVA-HCV Elicited in Mice High Immunogenicity in Spite of Reduced Host Gene Expression

Viruses, 2018
Hepatitis C virus (HCV) represents a major global health problem for which a vaccine is not available. Modified vaccinia virus Ankara (MVA)-HCV is a unique HCV vaccine candidate based in the modified vaccinia virus Ankara (MVA) vector expressing the ...
María Q. Marín, Patricia Pérez, Carmen E. Gómez, Carlos Óscar S. Sorzano, Mariano Esteban, Juan García-Arriaza   +5 more
doaj   +1 more source