Results 51 to 60 of about 9,189 (154)

Validation of a Point‐Of‐Care Ultrasound for Hepatitis Among Front‐Line Healthcare Workers Managing Chronic Hepatitis B Virus Infection in Zambia

Journal of Viral Hepatitis, Volume 33, Issue 9, September 2026.
ABSTRACT To close gaps in implementing care of people with hepatitis B virus (HBV) infection in resource‐limited settings, we evaluated the accuracy of a novel liver point‐of‐care ultrasound (POCUS) protocol for hepatitis (PUSH) among front‐line non‐radiology healthcare workers in Zambia. At University Teaching Hospital in Lusaka, Zambia, from March to
Costanza Bertoni, Annie Kanunga, Edford Sinkala, Enock Syabbalo, Helen Chitundu, Alick Chikwezi, Carolyn Chibundi, Guy K. Muula, Samuel Bosomprah, Nicolò Capra, Riccardo Lolatto, Giulia Morsica, Antonella Castagna, Claudia Wallrauch, Tom Heller, Michael J. Vinikoor   +15 more
wiley   +1 more source

Intrinsic disorder and oligomerization of the hepatitis delta virus antigen

Virology, 2010
The 195 amino acid basic protein (δAg) of hepatitis delta virus (HDV) is essential for replication of the HDV RNA genome. Numerous properties have been mapped to full-length δAg and attempts made to link these to secondary, tertiary and quaternary structures.
Alves, Carolina, Cheng, Hong, Roder, Heinrich, Taylor, John   +3 more
openaire   +2 more sources

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Cloning and expression of an immunodominant region of the hepatitis delta antigen

Journal of General Virology, 1990
A cDNA clone prepared from hepatitis delta virus (HDV) RNA extracted from human serum was subcloned in the bacterial expression vector pPL31 to produce a fusion protein consisting of the first 98 amino acids of MS2 polymerase and of 64 amino acids from near the N-terminal region of hepatitis delta antigen (HDAg).
J, Saldanha, E, Homer, R, Goldin, H C, Thomas, J, Monjardino   +4 more
openaire   +2 more sources

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

MedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge, Dong Han, Jing Wang, Xinyu Dai, Chen Ma, Feihong Chen   +5 more
wiley   +1 more source

Deciphering the Role of Post-Translational Modifications and Cellular Location of Hepatitis Delta Virus (HDV) Antigens in HDV-Mediated Liver Damage in Mice

Viruses
Hepatitis D virus (HDV) infection represents the most severe form of chronic viral hepatitis. We have shown that the delivery of HDV replication-competent genomes to the hepatocytes using adeno-associated virus (AAV-HDV) as gene delivery vehicles offers ...
Sheila Maestro, Nahia Gomez-Echarte, Gracian Camps, Carla Usai, Cristina Olagüe, Africa Vales, Rafael Aldabe, Gloria Gonzalez-Aseguinolaza   +7 more
doaj   +1 more source

The Relationship Between (Endo)cannabinoids, the Microbiome and Melanoma

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
CB1 and CB2 receptors are widely distributed in both normal and cancerous cells. Cannabinoids have a positive impact on reducing tumor growth in mice. A positive relationship exists between CB2 receptors and survival in skin melanoma. However, there is a negative impact on non‐small cell lung cancer and colon cancer, whereas a higher association of CB1
Farideh A. Javid, Marin Golčić, Anja Harej Hrkać, Andrej Belančić   +3 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Differential impact of hepatitis delta virus replication and expression of viral antigens on the cellular kinome profile

Cell Communication and Signaling
Background An infection with hepatitis D virus (HDV) is considered the most extreme form of viral hepatitis. Infection with HDV elicits strong increases in inflammation and hepatic injury, therefore pushing liver cirrhosis and development of ...
Keerthihan Thiyagarajah, Mirco Glitscher, Kai-Henrik Peiffer, Eberhard Hildt   +3 more
doaj   +1 more source

Cell cycle arrest mediated by hepatitis delta antigen

FEBS Letters, 1999
Hepatitis delta antigen (HDAg) is the only viral‐encoded protein of the hepatitis delta virus (HDV). This protein has been extensively characterized with respect to its biochemical and functional properties. However, the molecular mechanism responsible for persistent HDV infection is not yet clear.
Hwang, Soon B, Park, Kyu-Jin
openaire   +2 more sources