Results 111 to 120 of about 58,225 (243)

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Phylogenetic analysis of HDV isolates from HBsAg positive patients in Karachi, Pakistan

open access: yesVirology Journal, 2012
Background In spite of a high occurrence of Hepatitis Delta in the province of Sindh in Pakistan, no genetic study of Hepatitis Delta virus (HDV) isolates from this region was carried out.
Perveen Shadab   +4 more
doaj   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

open access: yesAggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Human Islet

open access: yes
Cell Proliferation, EarlyView.
Jiaqi Zou   +31 more
wiley   +1 more source

Why, Immunologically, Housing‐Related Fungi and Endotoxins (and Other Chronic Pro‐Inflammatory Stressors) Risk Latent Tuberculosis Reactivation, Severe Asthma, and Translocating and Invasive Infections in Indigenous Communities in Canada

open access: yesAmerican Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT Type 1/M1/TH1 and type 3/M1/TH17 pro‐inflammatory switches are risks for latent Mycobacterium tuberculosis (Mtb) reactivation and ongoing infection transmission. This paper considers the heavy toll of reactivation risk in Indigenous communities in Canada and the chronic, everyday pro‐inflammatory stressors connected with type 3/M1/TH17 immune ...
Stacie Burke
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Chronic Viral Hepatitis: Etiology, Pathogenesis of Liver Damage and Mechanisms of Persistence [PDF]

open access: yes, 2004
Chronic hepatotropic viruses commonly evade the antiviral defence systems of the body and cause a long - lasting persistent infection. The prolonged nature of the infection ensures that every infected person has ample opportunity to transmit the virus to
Setiabudi, I. (Irwan)
core  

Acute-on-chronic Liver Failure: MELD Score 30-day Mortality Predictability and Etiology in a Pakistani Population [PDF]

open access: yes, 2020
Background: Cirrhosis is a pathological condition that ultimately leads to liver failure. Acute on chronic liver failure (ACLF) has a high short term mortality rate. Viral hepatitis is the most common cause of liver failure in our local population.
Gilani, N. A. (Naeem)   +5 more
core  

Small Molecule‐Based Conditional Gene Regulation: Advances and Applications

open access: yesChemistry–Methods, Volume 6, Issue 4, April 2026.
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari   +3 more
wiley   +1 more source

Physical exercise mitigates chronic psychological stress‐induced vascular inflammation via the BDNF–Kif4–TARM1 axis

open access: yesClinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Schematic model of the potential mechanisms by which physical exercise alleviates stress‐induced vascular inflammation via the BDNF–Kif4–TARM1 axis, revealing a neuroimmune‐mediated brain–heart axis that supports exercise therapy for psychogenic coronary artery disease. This graphical abstract was drawn with the FigDraw tool (www.fgdraw.com).
Xianghui Zheng   +17 more
wiley   +1 more source

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