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Bulevirtide in the Treatment of Hepatitis Delta: Drug Discovery, Clinical Development and Place in Therapy [PDF]

Drug Design, Development and Therapy, 2023
Vicente Soriano,1 Victor Moreno-Torres,1,2 Ana Treviño,1 Octavio Corral,1 Carmen de Mendoza2 1Health Sciences School & Medical Center, Universidad Internacional La Rioja (UNIR), Madrid, Spain; 2Puerta de Hierro University Hospital & Research Institute ...
Carmen de Mendoza, Vicente Soriano, Víctor Moreno-Torres   +2 more
exaly   +4 more sources

Hepatitis Delta Virus Infection: An Overview [PDF]

Pathogens
The burden of hepatitis delta virus (HDV) infection is currently unknown and may affect 12 to 72 million people distributed across various hot spots in different regions of the globe. Screening for antibodies to HDV infection in patients positive for the
Vitor Duque, Diana Duque
doaj   +2 more sources

Molecular Characterization of Hepatitis Delta Virus in the Western Amazon, Acre, Brazil [PDF]

Viruses
Background: Hepatitis delta (HDV) is the most severe form of chronic viral hepatitis, with rapid progression to cirrhosis and hepatocellular carcinoma, and remains neglected in the Amazon Basin.
Rutilene Barbosa Souza, Thor Oliveira Dantas, Luiz Fellype Alves de Souza, Tárcio P. Roca, Adrhyan Araújo, Jackson A. S. Queiroz, Ana M. Passos-Silva, Mariana Araújo Costa, Edna Maria Gomes Gonçalves, Luis Edgardo Riveros Aguilar, Ana Alice Maia Gonçalves, Alexsandro Sobreira Galdino, Daniel Archimedes da Matta, Deusilene Vieira, Carlos Brites   +14 more
doaj   +2 more sources

Infection by Hepatitis Delta Virus [PDF]

Viruses, 2020
Hepatitis delta virus (HDV) and hepatitis B virus (HBV) are blood-borne viruses that infect human hepatocytes and cause significant liver disease. Infections with HBV are more damaging when there is a coinfection with HDV. The genomes and modes of replication of these two viruses are fundamentally different, except for the fact that, in nature, HDV ...
John M Taylor
exaly   +4 more sources

Alinity m, a Random-Access System, for Hepatitis B Virus DNA Quantification in Plasma and Whole Blood Collected on Dried Blood Spots

mSphere, 2022
The International Liver Association recommends the use of accurate and sensitive molecular methods for determination of hepatitis B virus (HBV) DNA levels in plasma or serum of chronic HBsAg carriers. The level of HBV replication represents the strongest
Valérie Ortonne, Quentin Lucas, Olivia Garrigou, Alexandre Soulier, Dominique Challine, Jean-Michel Pawlotsky, Vincent Leroy, Stéphane Chevaliez   +7 more
doaj   +1 more source

Diagnosis and Monitoring of Hepatitis B Virus Infection Using the Cobas^® HBV Test for Use on the Cobas^® 4800 System

Microorganisms, 2021
(1) Background: Sensitive and accurate nucleic acid amplification technologies are now recommended for hepatitis B virus (HBV) DNA detection and quantification in clinical practice to diagnose and monitor hepatitis B infection.
Valérie Ortonne, Mélanie Wlassow, Magali Bouvier-Alias, Giovana Melica, Jean-Dominique Poveda, Syria Laperche, Jean-Michel Pawlotsky, Stephane Chevaliez   +7 more
doaj   +1 more source

Therapy of Delta Hepatitis [PDF]

Cold Spring Harbor Perspectives in Medicine, 2015
Delta hepatitis is the less frequently encountered but most severe form of viral hepatitis. Acute delta hepatitis, as a result of coinfection with hepatitis B and hepatitis delta, is rare, but may lead to fulminant hepatitis, and no therapy exists for this form.
Cihan, Yurdaydin, Ramazan, Idilman
openaire   +2 more sources

Hepatitis B, C, and delta in the general population in Mayotte: hepatitis B as a major public health concern

BMC Infectious Diseases, 2022
Background Located in southwestern Indian Ocean, Mayotte is a French territory, with a very specific demographic, social and health context. To date, epidemiological data on infections by hepatitis B (HBV), C (HCV), and delta (HDV) viruses in Mayotte ...
Cécile Brouard, Fanny Parenton, Hassani Youssouf, Stéphane Chevaliez, Emmanuel Gordien, Maxime Jean, Mathias Bruyand, Sophie Vaux, Florence Lot, Marc Ruello, Unono Wa Maore group   +10 more
doaj   +1 more source

Delta hepatitis [PDF]

Expert Review of Anti-infective Therapy, 2009
Hepatitis delta virus (HDV) is a defective RNA virus that requires HBsAg for replication and transmission. It can cause acute or chronic hepatitis. Chronic infection with HDV is one of the most severe and difficult to treat forms of viral hepatitis. It has been estimated that there is a total of 15-20 million HDV carriers in the world.
openaire   +4 more sources

A Case Report of Hepatocellular Carcinoma 5 Years After HBsAg Loss in Chronic Hepatitis Delta: How Long Surveillance is Required?

Annals of Hepatology, 2017
Background: Hepatitis delta virus infection occurs as acute coinfection or as superinfection in patients with preexisting chronic hepatitis B. Chronic hepatitis delta leads to more severe disease than chronic hepatitis B, with more rapid progression of ...
Laura Escolà-Vergé, Mar Riveiro-Barciela, Maria Buti   +2 more
doaj   +1 more source