Results 61 to 70 of about 1,000,209 (254)

Pegylated interferon in the treatment of chronic delta hepatitis: the experience from real-world clinical practice

open access: yesAlʹmanah Kliničeskoj Mediciny, 2023
Rationale: The high prevalence of hepatitis D virus (HDV) infection in the Republic of Dagestan, significantly exceeding that in the European part of the Russian Federation, as well as the limited choice of therapeutic options, have led to the need to ...
Saniyat A. Magomedova   +9 more
doaj   +1 more source

Treating chronic hepatitis delta: The need for surrogate markers of treatment efficacy.

open access: yesJournal of Hepatology, 2019
Chronic hepatitis delta represents the most severe form of chronic viral hepatitis. The current treatment of hepatitis delta virus (HDV) infection consists of the use of interferons and is largely unsatisfactory.
C. Yurdaydın   +18 more
semanticscholar   +1 more source

Hepatitis delta virus propagation enabled by hepatitis C virus—Scientifically intriguing, but is it relevant to clinical practice?

open access: yesJournal of Viral Hepatitis, 2020
In vitro cell culture experiments and animal models have demonstrated that hepatitis delta virus (HDV) can theoretically propagate being enveloped by human pathogenic viruses other than hepatitis B virus (HBV), namely hepatitis C virus (HCV) and dengue ...
Lisa Sophie Pflüger   +3 more
semanticscholar   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication

open access: yesNature Communications, 2020
Hepatitis Delta virus (HDV) is a satellite of Hepatitis B virus with a single-stranded circular RNA genome. HDV RNA genome synthesis is carried out in infected cells by cellular RNA polymerases with the assistance of the small hepatitis delta antigen (S ...
Natali Abeywickrama-Samarakoon   +10 more
semanticscholar   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Human hepatic met-enkephalin and delta opioid receptor-1 immunoreactivities in viral and autoimmune hepatitis

open access: yesAnnals of Hepatology, 2008
Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella   +2 more
doaj   +1 more source

New epidemiology of hepatitis delta

open access: yesLiver international (Print), 2020
Hepatitis D virus (HDV) is a defective pathogen that needs hepatitis B virus (HBV) for infection. Co‐infection of HBsAg‐positive individuals with HDV is commonly associated with a more rapid progression to cirrhosis, a higher incidence of hepatocellular ...
J. Vlachogiannakos, G. Papatheodoridis
semanticscholar   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Experimental Drugs for the Treatment of Hepatitis D

open access: yesJournal of Experimental Pharmacology, 2021
Lisa Sandmann,1 Markus Cornberg1,2 1Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; 2Centre for Individualised Infection Medicine (CiiM), Helmholtz Centre for Infection Research, Braunschweig ...
Sandmann L, Cornberg M
doaj  

Home - About - Disclaimer - Privacy