Results 171 to 180 of about 20,970 (205)

Immunization of woodchucks with recombinant hepatitis delta antigen does not protect against hepatitis delta virus infection

Hepatology, 1990
To assess the role of immunization against hepatitis delta antigen in the prevention of hepatitis delta virus infection, woodchuck carriers of woodchuck hepatitis virus were immunized with a 64 amino acid portion of hepatitis delta antigen from its N-terminal region.
P, Karayiannis, J, Saldanha, J, Monjardino, R, Goldin, J, Main, S, Luther, M, Easton, A, Ponzetto, H C, Thomas   +8 more
openaire   +2 more sources

Elimination of hepatitis delta virus infection after loss of hepatitis B surface antigen in patients with chronic delta hepatitis

Journal of Medical Virology, 1994
AbstractThe aim of this study was to evaluate whether patients with chronic hepatitis delta virus (HDV) infection treated with alpha interferon and subsequent loss of hepatitis B surface antigen (HBsAg) eliminate HDV. HDV RNA was detected in 26 of 28 patients with chronic delta hepatitis using the polymerase chain reaction.
M, Battegay, L H, Simpson, J H, Hoofnagle, R, Sallie, A M, Di Bisceglie   +4 more
openaire   +2 more sources

Hepatitis Delta Antigen and RNA Polymerase II

2007
Replication and transcription of HDV proceed via RNA-dependent RNA synthesis. These reactions are thought to be catalyzed at least in part by host RNA polymerase II (RNAPII). Hepatitis delta antigen (HDAg), which is critical for these processes, was recently proposed to function as a transcription elongation factor for RNAPII.
Yuki Yamaguchi, Hiroski Handa
openaire   +1 more source

Delta-Interacting Protein A and the Origin of Hepatitis Delta Antigen

Science, 1997
Robert Brazas and Don Ganem ([1][1]) propose that the cellular protein, delta-interacting protein A (DIPA), interacts with hepatitis delta antigen (HDAg), affecting hepatitis delta virus (HDV) replication.
Manyuan Long, Sandro J de Souza, Walter Gilbert   +2 more
openaire   +1 more source

Stimulation of RNA Polymerase II Elongation by Hepatitis Delta Antigen

Science, 2001
Transcription elongation by RNA polymerase II (RNAPII) is negatively regulated by the human factors DRB-sensitivity inducing factor (DSIF) and negative elongation factor (NELF). A 66-kilodalton subunit of NELF (NELF-A) shows limited sequence similarity to hepatitis delta antigen (HDAg), the viral protein required for replication of hepatitis delta ...
Y.Yamaguchi, J.Filipovska, K.Yano, A.Furuya, N.Inukai, T.Narita, T.Wada, S. Sugimoto, M.M.Konarska, H. Handa.   +9 more
openaire   +2 more sources

Functional studies of hepatitis delta antigen and delta virus RNA.

Progress in clinical and biological research, 1991
We have sequenced an HDV RNA from an acute delta hepatitis patient from the Nauru Islands. By comparison with other HDV sequences previously reported, we have identified three conserved regions: the first one is the sequence around the catalytic cleavage site for genomic-sense RNA; the second is the corresponding site for the antigenomic sense RNA; and
M M, Lai, Y C, Chao, M F, Chang, J H, Lin, I, Gust   +4 more
openaire   +1 more source

Post-translational Modification of Delta Antigen of Hepatitis D Virus

2006
The hepatitis delta virus (HDV) genome has only one open reading frame, which encodes the viral small delta antigen. After RNA editing, the same open reading frame is extended 19 amino acids at the carboxyl terminus and encodes the large delta antigen.
W H, Huang, C W, Chen, H L, Wu, P J, Chen   +3 more
openaire   +2 more sources

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

Nature, 2021
Delphine Planas, Artem Baidaliuk, Florence Guivel-Benhassine   +2 more
exaly  

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

Nature, 2021
Steven A Kemp, Guido Papa, Rawlings P Datir   +2 more
exaly  

Cell entry and release of quasi-enveloped human hepatitis viruses

Nature Reviews Microbiology, 2023
, Xin Yin, Christopher Walker
exaly