Results 91 to 100 of about 32,123,782 (310)

Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein [PDF]

, 2010
The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 ...
Dubuisson, J., J. Dubuisson, A. H. Patel, G. Vieyres, Patel, A.H., Vieyres, G.   +5 more
core   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Hepatitis B virus reactivation sustained by a hepatitis B virus surface antigen immune-escape mutant isolate in a patient who was hepatitis B core antibody positive during treatment with sofosbuvir and velpatasvir for hepatitis C virus infection: a case report

Journal of Medical Case Reports, 2019
Background Although several cases of hepatitis B virus reactivation have been described in patients with a history of hepatitis B virus infection while undergoing treatment for hepatitis C virus infection with direct acting antivirals, the question of ...
Luca Foroghi Biland, Ludovica Ferrari, Vincenzo Malagnino, Elisabetta Teti, Carlotta Cerva, Adele Gentile, Marianna Aragri, Romina Salpini, Valentina Svicher, Massimo Andreoni, Loredana Sarmati   +10 more
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Hepatitis viral en la gestación

Revista Colombiana de Obstetricia y Ginecología, 1996
La primera causa de ictericia en el embarazo es la hepatitis viral que puede ser causada por lo menos por cinco virus (A, B, C, D y E). El descubrimiento del virus de la hepatitis C y Delta prácticamente eliminó las antes denominadas Hepatitis No A No B ...
Pío Iván Gómez Sánchez
doaj   +1 more source

Geographical and chronological origin and evolution of Hepatitis C Virus. [PDF]

, 2011
Hepatitis C Virus (HCV) infection is a major health problem that leads to cirrhosis and hepatocellular carcinoma. World over, more than 270-300 million people are estimated to be infected with the virus.
Sugunan V.S., amjesh revikumar, Achuthsankar S. Nair   +2 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

RELATIONSHIP BETWEEN HEV AND HCV INFECTIONS IN HEMODIALYSIS PATIENTS

Turkish Journal of Nephrology, 2019
The hemodialysis patients, having high risks for viral hepatitis have a prevalence of18% for hepatitis E virus and 41.5% for hepatitis C virus in our country.
Gülendam BOZDAYI, Hasibe VERDİ, Ülver DERİCİ, Murat DURANAY, Seyyal ROTA, Özden UZUNALİMOĞLU   +5 more
doaj  

Multiple Functions of Hepatitis E Virus ORF3

Microorganisms
Hepatitis E (Hepatitis E, HE) is an acute and chronic infectious hepatitis caused by hepatitis E virus (Hepatitis E Virus, HEV) infection, which is responsible for most acute hepatitis in the world and is a significant public health problem. The pathogen,
Fengyuan Jiao, Yu Zhao, Gengxu Zhou, Chi Meng, Lingjie Wang, Shengping Wu, Jixiang Li, Liting Cao, Bo Zhou, Yichen Luo, Hanwei Jiao   +10 more
doaj   +1 more source

The rise of the hepatitis E virus [PDF]

Journal of Hepatology, 2021
Vincent Mallet, Juan-Pablo Scarano Pereira, Alessandro Martinino, Anne-Marie Roque-Afonso   +3 more
openaire   +2 more sources