Results 101 to 110 of about 32,123,782 (310)

Requirement of Activation for Hepatitis B Virus Infection [PDF]

, 2007
Although _in vitro_ models of human hepatitis B virus replication are established, so far none could approximate infection efficiency as expected from _in vivo_ observations.
Claudia Maenz, Michael Bruns
core  

Hepatitis E as a Zoonosis

, 2016
Hepatitis E (HE) virus infection is not limited to spread from human to human but also occurs between animals and more importantly as zoonotic spread from animals to humans. Genotyping of strains from hepatitis E virus-infected patients has revealed that
Widén, Frederik,, Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Hepatitis E virus infection during pregnancy

Virology Journal, 2020
Background Hepatitis E virus (HEV) generally causes self-limiting viral hepatitis. However, in pregnant women, HEV infection can be severe and has been associated with up to 30% mortality in the third trimester.
Chunchen Wu, Xiaoxue Wu, Jianbo Xia
doaj   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

Hepatitis viruses in Kathmandu, Nepal: hospital-based study

BMC Research Notes, 2018
Objective The objective of this study was to see the aetiology and outcome of sporadic acute viral hepatitis (AVH) in Kathmandu, Nepal. Results Among 210 patients, 94 (45%) were male and 116 (55%) were female. Mean age was 30 years. 52 (24.7%) out of 210
Birendra Prasad Gupta, Anurag Adhikari, Santosh Chaudhary   +2 more
doaj   +1 more source

Hepatitis E Virus [PDF]

Transfusion Medicine and Hemotherapy, 2015
Pauli, Georg, Aepfelbacher, Martin, Bauerfeind, Ursula, Blümel, Johannes, Burger, Reinhard, Gärtner, Barbara, Gröner, Albrecht, Gürtler, Lutz, Heiden, Margarethe, Hildebrandt, Martin, Jansen, Bernd, Offergeld, Ruth, Schlenkrich, Uwe, Schottstedt, Volkmar, Seitz, Rainer, Strobel, Johanna, Willkommen, Hannelore, Baylis, Sally A.   +17 more
openaire   +3 more sources

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Comparative genomics of hepatitis A virus, hepatitis C virus, and hepatitis E virus provides insights into the evolutionary history of Hepatovirus species

MicrobiologyOpen, 2020
The intraspecies genomic diversity of the single‐strand RNA (+) virus species hepatitis A virus (Hepatovirus), hepatitis C virus (Hepacivirus), and hepatitis E virus (Orthohepevirus) was compared.
Trudy M. Wassenaar, Se‐Ran Jun, Michael Robeson, David W. Ussery   +3 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source