Results 111 to 120 of about 32,123,782 (310)

Comparative Pathology of Hepatitis A Virus and Hepatitis E Virus Infection

Cold Spring Harbor Perspectives in Medicine, 2018
Hepatitis A virus (HAV) and hepatitis E virus (HEV) cause acute, self-limiting hepatic infections that are usually spread by the fecal-oral route in humans. Naturally occurring and experimental infections are possible in a variety of nonhuman primates and, in the case of HEV, a number of other species. Many advances in understanding the pathogenesis of
John M, Cullen, Stanley M, Lemon
openaire   +3 more sources

Influence of IL-10RA and IL-22 polymorphisms on outcome of hepatitis C virus infection.

, 2007
BACKGROUND: Two receptor chains, IL-10RA and IL-10RB, are known to mediate the functions of interleukin-10 (IL-10), which has been shown to be involved in the progression of persistent hepatitis C virus (HCV) infection. Little information is available on
Thursz, Mark, Hill, Adrian V, Hill, Adrian, Knapp, S, Zhang, Lyna, Thomas, Howard C, Yee, LJ, Thomas, HC, Hennig, Branwen J, Wright, Mark, Yee, Leland J, Hennig, BJ, Frodsham, Angela J, Frodsham, AJ, Zhang, L, Wright, M, Hellier, Simon, Thursz, M, Knapp, Susanne, Hellier, S, Hill, AV   +20 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Human immunodeficiency virus and the liver: The impact of coinfection with hepatotropic viruses

Annals of Hepatology, 2019
Human immunodeficiency virus (HIV) predisposes for liver damage during coinfection with hepatitis E virus (HEV) and increases the replication of hepatitis C virus (HCV). HIV-hepatitis B virus (HBV) coinfections are common. In Mexico, hepatotropic viruses
Leonor Huerta, Julio Y. Anaya-Covarrubias, Nora A. Fierro   +2 more
doaj   +1 more source

Factors associated with testing for hepatitis C in an internet-recruited sample of men who have sex with men.

, 2001
BACKGROUND: Nearly 4 million individuals in the United States (1.8%) have been infected with hepatitis C virus, yet few are aware of their infection. GOAL: To identify correlates associated with hepatitis C virus testing among a sample of men who have ...
Diclemente, RJ, Hergenrather, KC, Rhodes, SD, Yee, LJ, KENNETH C. HERGENRATHER, SCOTT D. RHODES, LELAND J. YEE, RALPH J. DICLEMENTE   +7 more
core   +1 more source

Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]

, 2012
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A., Gordon, A, Scott Bowden, Pfafferott, K, Desmond, P.V., Ian R. James, Revill, P.A., Chopra, A, Mallal, SA, Silvana Gaudieri, Anna Ayres, Lewin, S.R., Thompson, AJ, Desmond, C.P., Jennifer Audsley, James, IR, Locarnini, SA, Stephen A. Locarnini, Sharon R. Lewin, James, I.R., Locarnini, S.A., Chivers, S., Christopher P. Desmond, Desmond, PV, Thompson, A.J., Stuart K. Roberts, Audsley, J, Revill, PA, Lau, GK, Gaudieri, S, Gaudieri, S., Audsley, J., Day, C, Caroline Day, Ayres, A, Day, C., Paul V. Desmond, Pfafferott, K., Gordon, A., Roberts, SK, Peter A. Revill, Alexander J. Thompson, Ayres, A., Desmond, CP, Sarah Chivers, Katja Pfafferott, Bowden, S., George K. Lau, Simon A. Mallal, Lewinb, SR, Lau, G.K., Roberts, S. K., Abha Chopra, Bowden, S, Mallal, S.A., Adam Gordon, Chivers, S   +56 more
core   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Infecção pelo HIV, hepatites B e C e sífilis em moradores de rua, São Paulo HIV infection, hepatitis B and C and syphilis in homeless people, in the city of São Paulo, Brazil

Revista de Saúde Pública, 2007
OBJETIVO: Estimar a prevalência das infecções pelo HIV, vírus das hepatites B e C, e da sífilis em moradores de rua. MÉTODOS: Estudo transversal com intervenção educativa, realizado no município de São Paulo, de 2002 a 2003.
Valquiria O. C. Brito, Deolinda Parra, Regina Facchini, Cassia Maria Buchalla   +3 more
doaj   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source