Results 101 to 110 of about 25,003 (247)

Nuevos conceptos sobre hepatocarcinoma

Oncología, 2022
Si bien el hepatocarcinoma, es considerado como uno de los cánceres menos frecuentes, no es menos cierto el hecho de que su incidencia se incrementa en distintas partes del mundo, esto principalmente debido a una cada vez más numerosa población de ...
Cecilia Abarca, Janine Aguilar, Gustavo Trujillo, Francisco Mendoza, Ernesto Paladines, Iván Nieto   +5 more
doaj  

Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1α and hypoxia-mediated mitophagy

OncoTarget, 2017
The antiangiogenic effects of sustained sorafenib treatment in hepatocellular carcinoma (HCC) lead to the occurrence of hypoxia-mediated drug resistance resulting in low therapy efficiency and negative outcomes.
Néstor Prieto‐Domínguez, C. Méndez-Blanco, Sara Carbajo‐Pescador, F. Fondevila, A. García-palomo, J. González‐Gallego, J. Mauriz   +6 more
semanticscholar   +1 more source

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

Environmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves, Matheus Mantuanelli Roberto, Adriana Fabiana Corrêa da Silva, Maria Aparecida Marin‐Morales   +3 more
wiley   +1 more source

Hepatocarcinoma diagnosis. Reflection is required

Revista Española de Enfermedades Digestivas, 2020
The editorial published in this same journal entitled "Sombras del tratamiento actual del hepatocarcinoma en España: una verdad incómoda" has awakened the need to review the available scientific literature on the precise diagnosis of hepatocarcinoma based on a clinical case. A 58-year-old male patient has a radiological finding in the left hepatic lobe
openaire   +2 more sources

Dual-Responsive Core Crosslinking Glycopolymer-Drug Conjugates Nanoparticles for Precise Hepatocarcinoma Therapy

Frontiers in Pharmacology, 2018
Nanoparticles (NPs) have demonstrated a potential for hepatocarcinoma therapy. However, the effective and safe NP-mediated drug transportation is still challenging due to premature leakage and inaccurate release of the drug.
Jing Wu, Jiayi Yuan, Baotong Ye, Yaling Wu, Zheng Xu, Jinghua Chen, Jingxiao Chen   +6 more
semanticscholar   +1 more source

Solamargine induces acute myeloid leukemia differentiation through TLR8 activation

VIEW, EarlyView.
SM, a steroidal alkaloid from Solanum nigrum L. has shown anticancer effect on various kinds of human cancer cells, yet its effect on leukemia cells remains unclear. This study examines antileukemic activities of SM in AML cells. Results indicate SM inhibits growth and promotes apoptosis of AML cells.
Qiaoyan Han, Yuting Chen, Zheyi Li, Yonglin Peng, Zhehan Hu, Yuliang Deng, Yanli Fu, Ming Cheng, Sheng Tan, Jing Tian, Xiaodong Zhao, Miao Sun   +11 more
wiley   +1 more source

HÿGADO GRASO NO ALCOHÿLICO

Revista Médica Clínica Las Condes, 2015
La esteatosis hepática no alcohólica es la acumulación excesiva de grasa en el hígado, en ausencia de causas secundarias y constituye la etiología frecuente de enfermedad hepática crónica sin terapia efectiva demostrada. La enfermedad incluye esteatosis,
LORENA CASTRO S., DRA., GUILLERMO SILVA P., DR.   +1 more
doaj   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

The Higher Incidence of Liver Injury in HCC Patients Compared to Other Malignancies During Immune-Checkpoint Inhibitor Therapy is Primarily Due to Tumor Progression

Therapeutics and Clinical Risk Management
Yan Wang,1,* Liwei Liu,2,* Mengyu Zhao,1,* Wei Chen,3 Yu Chen,2 Xinyan Zhao1 1Liver Research Center, Beijing Friendship Hospital, Key Laboratory on Translational Medicine on Cirrhosis, National Clinical Research Center for ...
Wang Y, Liu L, Zhao M, Chen W, Chen Y, Zhao X   +5 more
doaj  

Hepatocarcinoma. Hemoperitoneum

, 1974
Presentamos un caso de carcinoma primitivo de higado, en el cual destacamos: la forma de presentación clínica, la aparición de un hígado no cirrótico, la presencia de un hemoperitoneo, y la aparición multicéntrica del tumor.
Chifflet, Juan, Cassinelli, Daniel, Toledo, Nancy   +2 more
openaire   +1 more source