Results 11 to 20 of about 25,003 (247)
Drug Delivery, 2021 The effective delivery system plays an important role in the application of siRNA in the antitumor study. However, until now, researches on the delivery systems targeting hepatocarcinoma cells are still being explored.
Shuang Yang +4 more
semanticscholar +1 more source
Photothermal effects of CuS-BSA nanoparticles on H22 hepatoma-bearing mice
Frontiers in Pharmacology, 2022 The objective of this study was to evaluate the in vivo application and photothermal ablation effects and mechanism of copper sulfide nanoparticles (CuS NPs) in hepatocellular carcinoma (HCC).
Xinyu Dun +9 more
doaj +1 more source
Journal of Nanobiotechnology, 2021 Transcatheter arterial chemoembolization (TACE) is one of the main palliative therapies for advanced hepatocellular carcinoma (HCC), which is also regarded as a promising therapeutic strategy for cancer treatment. However, drug-loaded microspheres (DLMs),
Minjiang Chen +12 more
semanticscholar +1 more source
The Emerging Role of Ferroptosis in Liver Cancers
Life, 2022 Liver cancer represents a global health challenge with worldwide growth. Hepatocellular carcinoma (HCC) is the most common type of liver cancer. Indeed, approximately 90% of HCC cases have a low survival rate. Moreover, cholangiocarcinoma (CC) is another
Arianna Casini +9 more
doaj +1 more source
Deep Learning Algorithms in the Automatic Segmentation of Liver Lesions in Ultrasound Investigations
Life, 2022 Background: The ultrasound is one of the most used medical imaging investigations worldwide. It is non-invasive and effective in assessing liver tumors or other types of parenchymal changes.
Mădălin Mămuleanu +7 more
doaj +1 more source
Redox Biology, 2020 Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer metastasis. Its acting on phospholipid hydroperoxides and its phospholipase-A2 activity are unique among the peroxiredoxin family and add complexity to its action mechanisms ...
M. J. López-Grueso +8 more
semanticscholar +1 more source
NAFLD-Related Hepatocarcinoma: The Malignant Side of Metabolic Syndrome
Cells, 2021 Hepatocellular carcinoma (HCC) is the seventh most common cancer worldwide and the second leading cause of cancer-related mortality. HCC typically arises within a cirrhotic liver, but in about 20% of cases occurs in absence of cirrhosis.
A. Michelotti +8 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Background: Immunotherapy elicits durable responses in many tumors. Nevertheless, the positive response to immunotherapy always depends on the dynamic interactions between the tumor cells and infiltrating lymphocytes in the tumor microenvironment (TME ...
Jianhao Li +10 more
semanticscholar +1 more source
A Novel Graphene Quantum Dot‐Based mRNA Delivery Platform
ChemistryOpen, 2021 Abstract: During the last decades, there has been growing interest in using therapeutic messager RNA (mRNA) together with drug delivery systems. Naked, unformulated mRNA is, however, unable to cross the cell membrane and is susceptible to degradation ...
Ya Liu +6 more
doaj +1 more source
Alternative splicing of IRF3 plays an important role in the development of hepatocarcinoma
Epigenetics, 2023 Alternative splicing is a process causing mRNA translation to produce different proteins, and it is crucial for the development of tumours. In this study, we constructed a prognostic model related to alternative splicing events in hepatocarcinoma using ...
Zhenyi Lv +6 more
doaj +1 more source