Alternative splicing of IRF3 plays an important role in the development of hepatocarcinoma
Epigenetics, 2023 Alternative splicing is a process causing mRNA translation to produce different proteins, and it is crucial for the development of tumours. In this study, we constructed a prognostic model related to alternative splicing events in hepatocarcinoma using ...
Zhenyi Lv +6 more
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Revista de la Facultad de Medicina Humana, 2017 Objetivos: Determinar la sensibilidad y especificidad de la RMN trifásica con gadolinio en la detección de hepatocarcinoma en pacientes cirróticos que fueron a trasplante hepático y su correlación con los hallazgos del estudio patológico del explante ...
Consuelo Elsa Cornejo-Carrasco
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The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state [PDF]
, 2016 Indexación: Web of ScienceWith about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte ...
Alarcon, V +9 more
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Applied Sciences, 2021 Diethylamine nitrosamine (DEN), as an initiator of liver tumor, and carbon tetrachloride (CCl4), as a tumor promoter, have been used to study the molecular events of liver cancer in animal models.
Kiren Mustafa +10 more
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Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1-dependent mechanism [PDF]
, 2018 In cancer cells, global genomic hypomethylation is found together with localized hypermethylation of CpG islands within the promoters and regulatory regions of silenced tumor suppressor genes.
Billi, Monia +9 more
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Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
Life, 2021 Primary skin tumors are certainly more frequent than metastatic tumors, but the latter can sometimes be the first sign of otherwise unrecognized neoplastic pathology and always correspond to an advanced stage of the disease.
Gerardo Cazzato +7 more
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Oxidative stress contributes to cobalt oxide nanoparticles-induced cytotoxicity and DNA damage in human hepatocarcinoma cells. [PDF]
, 2013 BackgroundCobalt oxide nanoparticles (Co(3)O(4)NPs) are increasingly recognized for their utility in biological applications, magnetic resonance imaging, and drug delivery.
Ahamed, Maqusood +5 more
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Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies [PDF]
, 2013 PMCID: PMC3581439This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Trahtenherts +45 more
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Methylthioadenosine phosphorylase gene expression is impaired in human liver cirrhosis and hepatocarcinoma [PDF]
, 2004 Methylthioadenosine phosphorylase (MTAP) is a key enzyme in the methionine and adenine salvage pathways. In mammals, the liver plays a central role in methionine metabolism, and this essential function is lost in the progression from liver cirrhosis to ...
Avila, M.A. (Matías Antonio) +9 more
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Успехи молекулярной онкологии, 2017 Liver cancer is widespread neoplasm type that ranks second among the causes of cancer-related mortality worldwide. Hepatocellular carcinoma (HCC) is the main form of liver cancer generally detected at advanced stages in most patients.
A. S. Makarova
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