Results 21 to 30 of about 25,003 (247)
Journal of Cellular and Molecular Medicine, 2021 Abnormal glucose metabolism may contribute to cancer progression. As a member of the CRK (v‐crk sarcoma virus CT10 oncogene homologue) adapter protein family, CRKL (CRK‐like) associated with the development and progression of various tumours.
Chunmei Guo +8 more
semanticscholar +1 more source
Revista de la Facultad de Medicina Humana, 2017 Objetivos: Determinar la sensibilidad y especificidad de la RMN trifásica con gadolinio en la detección de hepatocarcinoma en pacientes cirróticos que fueron a trasplante hepático y su correlación con los hallazgos del estudio patológico del explante ...
Consuelo Elsa Cornejo-Carrasco
doaj +1 more source
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase
Cell Death and Disease, 2021 Metformin, the first-line drug for type II diabetes, has recently been considered an anticancer agent. However, the molecular target and underlying mechanism of metformin’s anti-cancer effects remain largely unclear.
Yinghui Wang +14 more
semanticscholar +1 more source
Applied Sciences, 2021 Diethylamine nitrosamine (DEN), as an initiator of liver tumor, and carbon tetrachloride (CCl4), as a tumor promoter, have been used to study the molecular events of liver cancer in animal models.
Kiren Mustafa +10 more
doaj +1 more source
Sodium Valproate Induces Cell Senescence in Human Hepatocarcinoma Cells
Molecules, 2013 Hepatocarcinogenesis is associated with epigenetic changes, including histone deacetylases (HDACs). Epigenetic modulation by HDAC inhibition is a potentially valuable approach for hepatocellular carcinoma treatment.
Hong-Mei An +4 more
doaj +1 more source
Gut, 2019 Objective Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular carcinoma (HCC). Design We investigated the functional contribution of fatty acid synthase
L. Che +25 more
semanticscholar +1 more source
Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
Life, 2021 Primary skin tumors are certainly more frequent than metastatic tumors, but the latter can sometimes be the first sign of otherwise unrecognized neoplastic pathology and always correspond to an advanced stage of the disease.
Gerardo Cazzato +7 more
doaj +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
Revista Médica del Uruguay, 2020 El hepatocarcinoma fibrolamelar es una entidad poco frecuente cuya incidencia varía entre 1% y 5% en el porcentaje de todos los hepatocarcinomas. Afecta principalmente a pacientes jóvenes con hígado sano, y en el 50% de los casos su diagnóstico se realiza en etapas avanzadas de la enfermedad. Se presenta el caso de un paciente de 15 años de edad, sano,
Martín Ferreira Pozzi +4 more
openaire +2 more sources
Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors
Experimental and Molecular Medicine, 2018 Sorafenib, a multikinase inhibitor with antiproliferative, antiangiogenic, and proapoptotic properties, constitutes the only effective first-line drug approved for the treatment of advanced hepatocellular carcinoma (HCC). Despite its capacity to increase
C. Méndez-Blanco +4 more
semanticscholar +1 more source