Results 1 to 10 of about 600,868 (344)

Clinical and pathological evaluation of fibrolamellar hepatocellular carcinoma: a single center study of 21 cases [PDF]

open access: yesClinics, 2015
OBJECTIVES: Fibrolamellar hepatocellular carcinoma is a rare primary malignant liver tumor that differs from conventional hepatocellular carcinoma in several aspects.
Aline Lopes Chagas   +10 more
doaj   +9 more sources

Immunohistochemical angiogenic biomarkers in hepatocellular carcinoma and cirrhosis: correlation with pathological features [PDF]

open access: yesClinics, 2016
OBJECTIVE To investigate immunohistochemical markers of angiogenesis and their association with pathological prognostic features in hepatocellular carcinoma and cirrhotic liver.
Osmar Damasceno Ribeiro   +2 more
doaj   +4 more sources

CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway

open access: yesJournal of Translational Medicine, 2023
Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide because of rapid progression and high incidence of metastasis or recurrence.
Chuanzheng Wang   +7 more
doaj   +1 more source

Resveratrol protects against chronic alcohol-induced liver disease in a rat model

open access: yesSTEMedicine, 2022
Hepatic ethanol metabolism participates in the pathogenesis of alcoholic liver disease (ALD). We aimed to evaluate the protecting effects and underlying mechanisms of Resveratrol against ALD.
Hanzhang Zhu   +3 more
doaj   +1 more source

A case of hepatocellular carcinoma recurring during pregnancy [PDF]

open access: yes, 2021
The hepatocellular carcinoma is more common in African and Asian countries with an incidence in women at around 5.5/10,000. Hepatocellular carcinoma is an aggressive tumour, with high recurrence rates, reaching around 50%.
Chatbi, Zaineb   +4 more
core   +2 more sources

Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK

open access: yesCell Death Discovery, 2023
HSPA13, an important member of the heat shock protein family, plays an essential role in the oncogenesis of many organs, but the mechanism and function in hepatocellular carcinoma (HCC) is still unclear.
Xuesong Cen   +9 more
doaj   +1 more source

β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation

open access: yesFrontiers in Oncology, 2021
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death globally. Currently there is a lack of tumor-selective and efficacious therapies for hepatocellular carcinoma. β-Lapachone (ARQ761 in clinical form) selectively kill NADPH:
Wenxiu Zhao   +15 more
doaj   +1 more source

RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31

open access: yesCell Death Discovery, 2022
RNF31 (HOIP), RBCK1 (HOIL-1L), and SHARPIN are subunits of the linear ubiquitin chain assembly complex. Their function and specific molecular mechanisms in hepatocellular carcinoma (HCC) have not been reported previously.
Xijun Chen   +5 more
doaj   +1 more source

Multi-Instance Multi-Label Learning for Gene Mutation Prediction in Hepatocellular Carcinoma [PDF]

open access: yes2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2020
Gene mutation prediction in hepatocellular carcinoma (HCC) is of great diagnostic and prognostic value for personalized treatments and precision medicine. In this paper, we tackle this problem with multi-instance multi-label learning to address the difficulties on label correlations, label representations, etc.
arxiv   +1 more source

Long Noncoding RNA HCAL Facilitates the Growth and Metastasis of Hepatocellular Carcinoma by Acting as a ceRNA of LAPTM4B

open access: yesMolecular Therapy: Nucleic Acids, 2017
Long noncoding RNAs (lncRNAs) are a new class of regulatory noncoding RNAs. Emerging evidences indicate that lncRNAs play a critical role in the development of hepatocellular carcinoma (HCC).
Cheng-Rong Xie   +10 more
doaj   +1 more source

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