Results 21 to 30 of about 941,442 (284)

Chemoembolization combined with pravastatin improves survival in patients with hepatocellular carcinoma [PDF]

open access: yes, 2008
BACKGROUND/AIMS: Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, has been shown to inhibit growth and to induce apoptosis in human hepatocellular carcinoma (HCC) cells.
Straub, Gundula   +27 more
core   +1 more source

Hepatocellular Carcinoma [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2015
The hepatitis B virus (HBV) is a widespread human pathogen that causes liver inflammation, cirrhosis, and hepatocellular carcinoma (HCC). Recent sequencing technologies have refined our knowledge of the genomic landscape and pathogenesis of HCC, but the mechanisms by which HBV exerts its oncogenic role remain controversial.
Marie-Annick, Buendia   +1 more
openaire   +2 more sources

Anti-angiogenesis in hepatocellular carcinoma treatment : current evidence and future perspectives [PDF]

open access: yes, 2011
Hepatocellular carcinoma (HCC) is among the most common cancer diseases worldwide. Arterial hypervascularisation is an essential step for HCC tumorigenesis and can be targeted by transarterial chemoembolization (TACE).
Trojan, Jörg, Welker, Martin-Walter
core   +1 more source

Multimodality Treatment for Early-Stage Hepatocellular Carcinoma: A Bridging Therapy for Liver Transplantation [PDF]

open access: yes, 2012
Purpose: To evaluate the efficiency of a multimodality approach consisting of transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) as bridging therapy for patients with hepatocellular carcinoma (HCC) awaiting orthotopic liver
Rentsch, M.   +33 more
core   +1 more source

Rising plasma nociceptin level during development of HCC: A case report [PDF]

open access: yes, 2004
AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis.
Horváth, Andrea   +8 more
core   +2 more sources

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development [PDF]

open access: yes, 2013
Background: Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and ...
Jörg Bojunga   +127 more
core   +3 more sources

Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa. [PDF]

open access: yes, 2010
The main objectives of this study were to define the occurrence and levels of hepatitis B virus (HBV) DNA in asymptomatic HBV carriers, cirrhosis patients and hepatocellular carcinoma (HCC) cases from The Gambia, and to evaluate the risk for cirrhosis or
Whittle, H   +23 more
core   +1 more source

Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma [PDF]

open access: yes, 2011
Background: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies ...
Polta, Andreas   +55 more
core   +2 more sources

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

open access: yes, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
Enrico N. De Toni   +32 more
core   +2 more sources

CDK5-mediated phosphorylation and stabilization of TPX2 promotes hepatocellular tumorigenesis

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background CDK5, an atypical member of the CDK family, play a significant role in the tumorigenesis of multiple organ, but CDK5 and its substrates in genesis and development of HCC is still unclear.
Fuqiang Wang   +10 more
doaj   +1 more source

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