Results 171 to 180 of about 541,993 (403)

Hepatic growth effects of methylprednisolone, azathioprine, mycophenolic acid, and mizoribine [PDF]

, 1993
Azzarone, A, Francavilla, A, Starzl, TE, Zeng, QH   +3 more
core   +1 more source

RNA‐Interference Approach to Study Functions of NADPH : Cytochrome P450 Oxidoreductase in Human Hepatocytes [PDF]

, 2009
Diana M. Feidt, Kathrin Klein, Andreas K. Nüssler, Ulrich M. Zanger   +3 more
openalex   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Effect of aqueous-alcoholic extract of Ducrosia Anethifolia Boiss on the fetal liver of diabetic rats

World Journal of Traditional Chinese Medicine
Objective: Moshgak (Ducrosia anethifolia) is a wild plant with medicinal value. The present study aimed to evaluate the effect of Moshgak on the liver tissue of the diabetic rat fetus.
Hossein Jahromi, Farangis Ghasemi, Elmira Mikaeiliagah   +2 more
doaj   +1 more source

3D-printed gelatin scaffolds of differing pore geometry modulate hepatocyte function and gene expression

, 2018
Phillip L. Lewis, Richard M. Green, Ramille N. Shah   +2 more
openalex   +2 more sources

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

Hepatotrophic properties in dogs of human FKBP, the binding protein for FK506 and rapamycin [PDF]

, 1991
Albers, MW, Foglieni, CS, Francavilla, A, Porter, KA, Schreiber, SL, Starzl, TE   +5 more
core   +1 more source

High frequency and long persistency of ballooning hepatocyte were associated with glucose intolerance in patients with severe obesity [PDF]

, 2021
Keisuke Kakisaka, Akira Sasaki, Akira Umemura, Haruka Nikai, Yuji Suzuki, Masao Nishiya, Tamotsu Sugai, Hiroyuki Nitta, Yasuhiro Takikawa   +8 more
openalex   +1 more source