Біологія тварин, 2022 Herbal preparations recommended in the treatment protocols for metabolic disorders are highly effective and less toxic than chemically synthesized ones.
M. A. Lieshchova +2 more
doaj +1 more source
Veterinární Medicína, 2021 This study analysed the effect of cottonseed hulls and chitosan in diets for lambs by determining the blood metabolite profile, and the histopathology of the kidney, liver, and rumen.
T Silva Magalhaes +11 more
doaj +1 more source
The developmental gene Chordin is amplified and expressed in human cancers
Molecular & Cellular Oncology, 2023 Chordin (CHRD) is a secreted protein important in early development, yet a role for CHRD in human disease has not been identified. In this study we investigated CHRD in cancer and normal adult tissues using the wealth of genome-wide data available in ...
Eric Sosa, Edward M. De Robertis
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Molecular Therapy: Methods & Clinical Development, 2023 Lipid nanoparticles (LNPs) for delivery of mRNA usually contain ionizable lipid/helper lipid/cholesterol/PEG-lipid in molar ratios of 50:10:38.5:1.5, respectively.
Nisha Chander +4 more
doaj +1 more source
Different response to epidermal growth factor of hepatocytes in cultures isolated from male or female rat liver. Inhibitor effect of estrogen on binding and mitogenic effect of epidermal growth factor [PDF]
, 1987 Deoxyribonucleic acid (DNA) synthesis in hepatocytes isolated from the livers of male and female rats has been compared in monolayer culture. Plating efficiency, DNA and protein content, viability, and morphologic appearance were the same in cultures ...
Coetzee, M +8 more
core +1 more source
Metabolism of low-density lipoproteins by cultured hepatocytes from normal and homozygous familial hypercholesterolemic subjects [PDF]
, 1986 The profoundly elevated concentrations of low-density lipoproteins (LDL) present in homozygous familial hypercholesterolemia lead to symptomatic cardiovascular disease and death by early adulthood.
Brewer, HB +6 more
core +1 more source
Wharton’s Jelly Mesenchymal Stem Cell: Various Protocols for Isolation and Differentiation of Hepatocyte-Like Cells; Narrative Review [PDF]
Iranian Journal of Medical Sciences, 2019 There are several differentiation methods for mesenchymal stem cells (MSCs) into hepatocyte-like cell. Investigators reported various hepatic differentiation protocols such as modifying culturing conditions or using various growth factors/cytokines.
Negar Varaa +3 more
doaj +1 more source
Autophagy: A cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress [PDF]
, 2012 The role of autophagy in the response of human hepatocytes to oxidative stress remains unknown. Understanding this process may have important implications for the understanding of basic liver epithelial cell biology and the responses of hepatocytes ...
Biederbick A +7 more
core +1 more source
Development and characterization of a new human hepatic cell line [PDF]
, 2015 The increasing demand and hampered use of primary human hepatocytes for research purposes have urged scientists to search for alternative cell sources, such as immortalized hepatic cell lines.
Berx, Geert +6 more
core +3 more sources
Recent Advances in Models of Immune-Mediated Drug-Induced Liver Injury
Frontiers in Toxicology, 2021 Hepatic inflammation is a key feature of a variety of liver diseases including drug-induced liver injury (DILI), orchestrated by the innate immune response (Kupffer cells, monocytes, neutrophils, dendritic cells) and the adaptive immune system (T cells ...
Farah Tasnim +18 more
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