Results 1 to 10 of about 281,999 (311)
Histology and histopathology, 1995 Ductular hepatocytes are observed in the livers of both experimental animals and man under various conditions of severe toxin-, carcinogen- or viral-induced hepatic injury with prominent loss of parenchymal hepatocytes. These unique hepatic epithelial cells are characterized by phenotypic traits that are intermediate between those of hepatocytes and ...
Sirica, A.E.
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The Efficacy of the Hepatocyte Spheroids for Hepatocyte Transplantation [PDF]
Cell Transplantation, 2021 The safety and short-term efficacy of hepatocyte transplantation (HCTx) have been widely proven. However, issues such as reduced viability and/or function of hepatocytes, insufficient engraftment, and lack of a long-term effect have to be overcome for widespread application of HCTx. In this study, we evaluated hepatocyte spheroids (
Kazuaki Shibuya +5 more
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Hepatocyte transplantation [PDF]
American Journal of Transplantation, 2004 Numerous laboratory studies have shown that hepatocyte transplantation may serve as an alternative to organ transplantation for patients with life-threatening liver disease. Because of the successes of experimental hepatocyte transplantation, institutions have attempted to use this therapy in the clinic for the treatment of a variety of hepatic ...
Ira J, Fox, Jayanta, Roy-Chowdhury
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Біологія тварин, 2022 Herbal preparations recommended in the treatment protocols for metabolic disorders are highly effective and less toxic than chemically synthesized ones.
M. A. Lieshchova +2 more
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Veterinární Medicína, 2021 This study analysed the effect of cottonseed hulls and chitosan in diets for lambs by determining the blood metabolite profile, and the histopathology of the kidney, liver, and rumen.
T Silva Magalhaes +11 more
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The developmental gene Chordin is amplified and expressed in human cancers
Molecular & Cellular Oncology, 2023 Chordin (CHRD) is a secreted protein important in early development, yet a role for CHRD in human disease has not been identified. In this study we investigated CHRD in cancer and normal adult tissues using the wealth of genome-wide data available in ...
Eric Sosa, Edward M. De Robertis
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Isolated Hepatocytes versus Hepatocyte Spheroids: In Vitro Culture of Rat Hepatocytes [PDF]
Cell Transplantation, 2005 The use of hepatocytes that express liver-specific functions to develop an artificial liver is promising. Unfortunately, the loss of specialized liver functions (dedifferentiation) is still a major problem. Different techniques, such as collagen entrapment, spherical multicellular aggregates (spheroids), and coculture of hepatocytes with extracellular ...
Giovanni Ambrosino +5 more
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Molecular Therapy: Methods & Clinical Development, 2023 Lipid nanoparticles (LNPs) for delivery of mRNA usually contain ionizable lipid/helper lipid/cholesterol/PEG-lipid in molar ratios of 50:10:38.5:1.5, respectively.
Nisha Chander +4 more
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High density culturing of porcine hepatocytes immobilized on nonwoven polyurethane-based biomatrices [PDF]
, 2001 Objective: Hepatocytes are increasingly used as functional units in bioartificial liver devices. The objective of the present study was to investigate the feasibility of culturing porcine hepatocytes in high density on a novel polyurethane-based nonwoven
Gomez-Lechon, M. J. +6 more
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Wharton’s Jelly Mesenchymal Stem Cell: Various Protocols for Isolation and Differentiation of Hepatocyte-Like Cells; Narrative Review [PDF]
Iranian Journal of Medical Sciences, 2019 There are several differentiation methods for mesenchymal stem cells (MSCs) into hepatocyte-like cell. Investigators reported various hepatic differentiation protocols such as modifying culturing conditions or using various growth factors/cytokines.
Negar Varaa +3 more
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