Results 11 to 20 of about 233,279 (266)
The Efficacy of the Hepatocyte Spheroids for Hepatocyte Transplantation [PDF]
Cell Transplantation, 2021 The safety and short-term efficacy of hepatocyte transplantation (HCTx) have been widely proven. However, issues such as reduced viability and/or function of hepatocytes, insufficient engraftment, and lack of a long-term effect have to be overcome for widespread application of HCTx. In this study, we evaluated hepatocyte spheroids (
Kazuaki Shibuya +5 more
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Hepatocyte transplantation [PDF]
American Journal of Transplantation, 2004 Numerous laboratory studies have shown that hepatocyte transplantation may serve as an alternative to organ transplantation for patients with life-threatening liver disease. Because of the successes of experimental hepatocyte transplantation, institutions have attempted to use this therapy in the clinic for the treatment of a variety of hepatic ...
Ira J, Fox, Jayanta, Roy-Chowdhury
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Isolated Hepatocytes versus Hepatocyte Spheroids: In Vitro Culture of Rat Hepatocytes [PDF]
Cell Transplantation, 2005 The use of hepatocytes that express liver-specific functions to develop an artificial liver is promising. Unfortunately, the loss of specialized liver functions (dedifferentiation) is still a major problem. Different techniques, such as collagen entrapment, spherical multicellular aggregates (spheroids), and coculture of hepatocytes with extracellular ...
Giovanni Ambrosino +5 more
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Revista Española de Enfermedades Digestivas, 2019 We have read with great interest the study by Vera MC et al. on the intrasplenic transplantation of hepatocytes from donors receiving the carcinogenic drugs diethylnitrosamine (DEN) and 2-actylaminofluorene (2-AAF). The most important conclusion of the study is that there were no signs of tumor progression in the recipient liver at seven and 60 days ...
Javier A, Cienfuegos +2 more
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Cytomorphological Changes in the Hepate of the White Sea Coastal Cod (Gadus morhua maris-albi Derjugin, 1920) during Parasitic Invasions [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2015 The cod Gadus morhua maris-albi is one of the most heavily infested fish species in the White Sea. The fish liver (hepate) is a convenient model to study the pathogenesis in parasitosis.
Shakurova N.V., Kudryavtseva E.V.
doaj
Poultry Science, 2020 In avian species, liver lipid metabolism plays an important role in egg laying performance. Previous studies indicate that betaine supplementation in laying hens improves egg production.
Nagmeldin A. Omer +7 more
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Signaling Nodes Associated with Endoplasmic Reticulum Stress during NAFLD Progression
Biomolecules, 2021 Excess and sustained endoplasmic reticulum (ER) stress, paired with a failure of initial adaptive responses, acts as a critical trigger of nonalcoholic fatty liver disease (NAFLD) progression.
Ja Hyun Koo, Chang Yeob Han
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Hepatocyte Transplantation [PDF]
Journal of Clinical and Experimental Hepatology, 2011 Hepatocyte transplantation (HTx) has been developed for use in liver-based metabolic disorders and in acute liver failure. Worldwide, there are around 80 patients that have been transplanted with hepatocytes. Almost all reported studies prove feasibility and safety of the procedure with short- to medium-term success.
Ragai R, Mitry +2 more
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3D Hepatic Organoid-Based Advancements in LIVER Tissue Engineering
Bioengineering, 2021 Liver-associated diseases and tissue engineering approaches based on in vitro culture of functional Primary human hepatocytes (PHH) had been restricted by the rapid de-differentiation in 2D culture conditions which restricted their usability.
Amit Panwar, Prativa Das, Lay Poh Tan
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Molecules, 2018 There is growing interest regarding the use of herbal preparations based on Cannabis sativa for medicinal purposes, despite the poorly understood interactions of their main constituent Δ9-tetrahydrocannabinol (THC) with conventional drugs ...
Ana Lucić Vrdoljak +11 more
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