Results 21 to 30 of about 411,384 (307)
Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]
, 2015 Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S. +3 more
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Cell Reports, 2021 Summary: Chronic injury to hepatocytes results in inflammation, steatohepatitis, fibrosis, and nonalcoholic fatty liver disease (NAFLD). The tetraspanin TM4SF5 is implicated in fibrosis and cancer.
Eunmi Kim +10 more
doaj +1 more source
A fresh look at augmenter of liver regeneration in rats. [PDF]
, 1999 Augmenter of liver regeneration (ALR) is a hepatotrophic protein originally identified by bioassay in regenerating rat and canine livers following partial hepatectomy and in the hyperplastic livers of weanling rats, but not in resting adult livers.
Abyss +86 more
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Hepatocyte Transplantation [PDF]
Journal of Clinical and Experimental Hepatology, 2011 Hepatocyte transplantation (HTx) has been developed for use in liver-based metabolic disorders and in acute liver failure. Worldwide, there are around 80 patients that have been transplanted with hepatocytes. Almost all reported studies prove feasibility and safety of the procedure with short- to medium-term success.
Ragai R, Mitry +2 more
openaire +2 more sources
Mechanisms of transcriptional control of glucose metabolism in hepatocytes
Сахарный диабет, 2016 The hepatic tissue plays a key role in the regulation and maintenance of stable blood glucose levels. The liver is the main gluconeogenesis organ of the body and is under constant hormonal control to determine the metabolic activity of hepatocytes ...
Konstantin Y. Kulebyakin +3 more
doaj +1 more source
The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis [PDF]
, 2016 Although necrosis and necroinflammation are central features of many liver diseases, the role of programmed necrosis in the context of inflammation-dependent hepatocellular death remains to be fully determined.
Andreas E. Kremer +24 more
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Cytomorphological Changes in the Hepate of the White Sea Coastal Cod (Gadus morhua maris-albi Derjugin, 1920) during Parasitic Invasions [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2015 The cod Gadus morhua maris-albi is one of the most heavily infested fish species in the White Sea. The fish liver (hepate) is a convenient model to study the pathogenesis in parasitosis.
Shakurova N.V., Kudryavtseva E.V.
doaj
Poultry Science, 2020 In avian species, liver lipid metabolism plays an important role in egg laying performance. Previous studies indicate that betaine supplementation in laying hens improves egg production.
Nagmeldin A. Omer +7 more
doaj +1 more source
Signaling Nodes Associated with Endoplasmic Reticulum Stress during NAFLD Progression
Biomolecules, 2021 Excess and sustained endoplasmic reticulum (ER) stress, paired with a failure of initial adaptive responses, acts as a critical trigger of nonalcoholic fatty liver disease (NAFLD) progression.
Ja Hyun Koo, Chang Yeob Han
doaj +1 more source
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites. [PDF]
, 2019 Synthetic cannabinoids (SCs) were initially developed as pharmacological tools to probe the endocannabinoid system and as novel pharmacotherapies, but are now highly abused.
Diao, Xingxing, Huestis, Marilyn A.
core +2 more sources