Results 21 to 30 of about 233,279 (266)
Molecules, 2021 Obesity has a strong relationship to insulin resistance and diabetes mellitus, a chronic metabolic disease that alters many physiological functions. Naturally derived drugs have aroused great interest in treating obesity, and triterpenoids are natural ...
Norman Balcazar +6 more
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Ethanol Disrupts the Protective Crosstalk Between Macrophages and HBV-Infected Hepatocytes
BiomoleculesAbout 296 million people worldwide are living with chronic hepatitis B viral (HBV) infection, and outcomes to end-stage liver diseases are potentiated by alcohol.
Murali Ganesan +5 more
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The sensitivity of cells with the various level of NAD(P)H:quinone oxidoreductase 1 to cytotoxic action of quinonimines and α-тоcopherol synthetic derivatives [PDF]
The Ukrainian Biochemical Journal, 2015 The effects of α-tocopherol with shortened to 6 carbon atoms side chain (α-Toc-C6), α-tocopherol succinate (α-TS) and quinonimine 2,6-dichlorophenolindophenol (DCPIP) on DT-diaphorase activity and viability of rat thymocytes, splenocytes and hepatocytes ...
G. V. Petrova, А. V. Parshykov
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Viruses, 2021 Co-infection with the hepatitis B virus and hepatitis delta virus (HDV) leads to the most aggressive form of viral hepatitis. Using in vitro infection models, we confirmed that IL-1β, a crucial innate immune molecule for pathogen control, was very potent
Marion Delphin +6 more
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Liver Cell Mitophagy in Metabolic Dysfunction-Associated Steatotic Liver Disease and Liver Fibrosis
AntioxidantsMetabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately one-third of the global population. MASLD and its advanced-stage liver fibrosis and cirrhosis are the leading causes of liver failure and liver-related death worldwide.
Jiaxin Chen +5 more
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Hepatitis C, Innate Immunity and Alcohol: Friends or Foes?
Biomolecules, 2015 Hepatitis C and alcohol are the most widespread causes of liver disease worldwide. Approximately 80% of patients with a history of hepatitis C and alcohol abuse develop chronic liver injury.
Natalia A. Osna +2 more
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Pathophysiology and Treatment Options for Hepatic Fibrosis: Can It Be Completely Cured?
Cells, 2021 Hepatic fibrosis is a dynamic process that occurs as a wound healing response against liver injury. During fibrosis, crosstalk between parenchymal and non-parenchymal cells, activation of different immune cells and signaling pathways, as well as a ...
Arshi Khanam +2 more
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Effect of Thermal Stress on Caprine Hepatocyte’s Antioxidant Enzymes Activity and TGF β Secretion In Vitro [PDF]
Journal of Stress Physiology & Biochemistry, 2014 Liver is involved in several vital functions such as synthesis, secretion, storage and metabolism of plasma proteins and in detoxifying functions. In the present study, hepatocytes were obtained by disaggregation of caprine liver caudate lobe.
Phad Ashok Vyankati, Anand Laxmi
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Journal of Lipid Research, 2006 Scavenger receptor class B type I (SR-BI) plays a critical role in the delivery of HDL cholesterol and cholesteryl esters (CEs) to liver and steroidogenic tissues by a selective process that does not result in significant degradation of HDL protein ...
Chris J. Harder +3 more
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Impact of HCV Infection on Hepatocyte Polarity and Plasticity
Pathogens, 2022 The hepatitis C virus (HCV) is an oncogenic virus that alters the cell polarization machinery in order to enter the hepatocyte and replicate. While these alterations are relatively well defined, their consequences in the evolution of the disease remain ...
Jean Agnetti +2 more
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