Results 21 to 30 of about 281,999 (311)

Cytomorphological Changes in the Hepate of the White Sea Coastal Cod (Gadus morhua maris-albi Derjugin, 1920) during Parasitic Invasions [PDF]

Учёные записки Казанского университета: Серия Естественные науки, 2015
The cod Gadus morhua maris-albi is one of the most heavily infested fish species in the White Sea. The fish liver (hepate) is a convenient model to study the pathogenesis in parasitosis.
Shakurova N.V., Kudryavtseva E.V.
doaj  

Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor–mediated activation of hepatic lipogenesis-related genes

Poultry Science, 2020
In avian species, liver lipid metabolism plays an important role in egg laying performance. Previous studies indicate that betaine supplementation in laying hens improves egg production.
Nagmeldin A. Omer, Yun Hu, Abdulrahman A. Idriss, Halima Abobaker, Zhen Hou, Shu Yang, Wenqiang Ma, Ruqian Zhao   +7 more
doaj   +1 more source

Signaling Nodes Associated with Endoplasmic Reticulum Stress during NAFLD Progression

Biomolecules, 2021
Excess and sustained endoplasmic reticulum (ER) stress, paired with a failure of initial adaptive responses, acts as a critical trigger of nonalcoholic fatty liver disease (NAFLD) progression.
Ja Hyun Koo, Chang Yeob Han
doaj   +1 more source

Toxicity of microcystins in the isolated hepatocytes of common carp (Cyprinus carpio L.) [PDF]

, 2007
The toxicity of hepatotoxic microcystins produced mainly by Microcystis aeruginosa in mammals and fishes was well studied in recent years. However, there were scarcely reports in toxic effects of microcystins on isolated hepatocytes of fishes, especially
Li, Xiao-Yu, Li, XY, Henan Normal Univ, Coll Life Sci, 46 Jianshe Rd, Xinxiang 453007, Henan, Peoples R China, Liu, Yong-Ding, Liang, Jun-Bo, Wang, Jie   +4 more
core   +1 more source

Effect of different doses of paricalcitol on the expression of vitamin D receptors in mice liver tissue

Разработка и регистрация лекарственных средств, 2023
Introduction. The high doses of vitamin D lead to undesirable side effects such as hypercalcemia. Paricalcitol (PC) is a biologically active synthetic substance that selectively binds to intracellular vitamin D receptors and does not cause hypercalcemia.
T. P. Sataieva, V. Yu. Malygina, A. A. Davydova, M. A. Kriventsov, A. K. Gurtovaya   +4 more
doaj   +1 more source

Irinotecan and Δ9-Tetrahydrocannabinol Interactions in Rat Liver: A Preliminary Evaluation Using Biochemical and Genotoxicity Markers

Molecules, 2018
There is growing interest regarding the use of herbal preparations based on Cannabis sativa for medicinal purposes, despite the poorly understood interactions of their main constituent Δ9-tetrahydrocannabinol (THC) with conventional drugs ...
Ana Lucić Vrdoljak, Nino Fuchs, Anja Mikolić, Suzana Žunec, Irena Brčić Karačonji, Andreja Jurič, Ljerka Prester, Vedran Micek, Marijana Neuberg, Samir Čanović, Gordan Mršić, Nevenka Kopjar   +11 more
doaj   +1 more source

3D Hepatic Organoid-Based Advancements in LIVER Tissue Engineering

Bioengineering, 2021
Liver-associated diseases and tissue engineering approaches based on in vitro culture of functional Primary human hepatocytes (PHH) had been restricted by the rapid de-differentiation in 2D culture conditions which restricted their usability.
Amit Panwar, Prativa Das, Lay Poh Tan
doaj   +1 more source

Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict drug induced hepatotoxicity

, 2013
Human hepatocytes are the gold standard for toxicological studies but they have several drawbacks, like scarce availability, high inter-individual variability, a short lifetime, which limits their applicability.
Jemnitz, Katalin, Monika Szabo, Katalin Jemnitz, Veres, Zsuzsa, Zsuzsa Veres, Baranyai, Zsolt, Zsolt Baranyai, Szabo, Monika, Ferenc Jakab, Jakab, Ferenc   +9 more
core   +1 more source

Ursolic Acid Lactone Obtained from Eucalyptus tereticornis Increases Glucose Uptake and Reduces Inflammatory Activity and Intracellular Neutral Fat: An In Vitro Study

Molecules, 2021
Obesity has a strong relationship to insulin resistance and diabetes mellitus, a chronic metabolic disease that alters many physiological functions. Naturally derived drugs have aroused great interest in treating obesity, and triterpenoids are natural ...
Norman Balcazar, Laura I. Betancur, Diana L. Muñoz, Frankly J. Cabrera, Adriana Castaño, Luis F. Echeverri, Sergio Acin   +6 more
doaj   +1 more source

Ethanol Disrupts the Protective Crosstalk Between Macrophages and HBV-Infected Hepatocytes

Biomolecules
About 296 million people worldwide are living with chronic hepatitis B viral (HBV) infection, and outcomes to end-stage liver diseases are potentiated by alcohol.
Murali Ganesan, Anup S. Pathania, Grace Bybee, Kusum K. Kharbanda, Larisa Y. Poluektova, Natalia A. Osna   +5 more
doaj   +1 more source