Results 251 to 260 of about 380,993 (362)

Dynamic dual regulation of amphiregulin in liver pathophysiology: balancing regeneration and disease progression via the EGFR axis. [PDF]

Front Med (Lausanne)
Wang YL, Zhou DJ, Wang QW, Zhang Y, Yang WJ, Tan WJ, Wang HY, Chen XW, Li SQ.   +8 more
europepmc   +1 more source

Emulsion Templated Porous Polymers as Scaffolds for 3D Hepatocyte Culture [PDF]

, 2014
Adam S. Hayward
openalex  

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

Advanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu, Ju‐Chan Park, Heesoo Uhm, Yong‐Woo Kim, Hyeon Woo Im, Sangsu Bae   +5 more
wiley   +1 more source

Organoids for Metabolic Disease Modeling. [PDF]

J Inherit Metab Dis
Ardisasmita AI, Nieuwenhuis EES, Fuchs SA.   +2 more
europepmc   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

Non-disruptive in vitro monitoring of cellular states with cell-free DNA methylation. [PDF]

Genome Biol
Hess A, Kovacsovics A, Bachinger F, Vallier L, Kretzmer H, Meissner A.   +5 more
europepmc   +1 more source

An experimental method for rapid growth of liver in spleen. The survival and proliferation of chemically induced preneoplastic hepatocytes in spleen.

, 1983
S. D. Finkelstein, G Lee, Alexandra Medline, Masae Tatematsu, L Makowka, Emmanuel Farber   +5 more
openalex   +1 more source

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source

Correction to "Beyond the Michaelis-Menten: Evaluation of a tQSSA-Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance from Hepatocyte Assays". [PDF]

CPT Pharmacometrics Syst Pharmacol
europepmc   +1 more source

Heat stroke and the liver: mechanisms of injury and therapeutic strategies. [PDF]

Eur J Med Res
Dou J, Cui Q, Li W, Jia K, Wang F.
europepmc   +1 more source