Results 261 to 270 of about 541,993 (403)

Non-A, Non-B (Type 1) Hepatitis Agent Capable of Inducing Tubular Ultrastructures in the Hepatocyte Cytoplasm of Chimpanzees: Inactivation by Formalin and Heat

, 1982
Hiroshi Yoshizawa, Yukio Itoh, Shigenori Iwakiri, Koji Kitajima, Akira Tanaka, Toshiaki Tachibana, Tetsuo Nakamura, Yuzo Miyakawa, Makoto Mayumi   +8 more
openalex   +1 more source

Features of experimental modeling of ferroptosis of hepatocytes

, 2022
V. S. Ponamarev
openalex   +2 more sources

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

<p>[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis<br><br></p>. [PDF]

Int J Mol Med
Yang Y, Du X, Wang Q, Liu J, Zhang E, Sai L, Peng C, Lavin MF, Yeo AJ, Yang X, Shao H, Du Z.   +11 more
europepmc   +1 more source

Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation [PDF]

, 2017
Galemmo, Robert A, Jr, Han, Zhenfu, Janetka, James W, Klampfer, Lidija, Owusu, Benjamin Y, Thomas, Shantasia, Venukadasula, Phanindra   +6 more
core   +2 more sources

Decoding hepatocyte ploidy [PDF]

Nature Reviews Gastroenterology & Hepatology, 2018
openaire   +2 more sources

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

SWI/SNF Chromatin Remodelling Complex in Hepatic Physiology: Mechanistic Insights Into Development, Homeostasis and Pathogenesis. [PDF]

J Cell Mol Med
Li R, Zhang B, Wei X, Yang J, Zhou Y.
europepmc   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Plastic hepatocyte states limit liver cancer development. [PDF]

Nat Commun
Strathearn LS, Hayata Y, Illendula A, Hewett CK, Chen M, He G, Escribano-Cebrián M, Jarboe B, Gómez-Tomé L, de Prisco N, Slifker M, Kawamura S, Nakagawa H, Rossell D, Stanger BZ, Font-Burgada J.   +15 more
europepmc   +1 more source