Results 271 to 280 of about 380,993 (362)

Innovative Metasurface Colorimetric Cell‐on‐a‐Chip Sensor for Continuous, Label‐Free, Non‐Destructive Assessment of Intestinal Barrier Dynamics

Advanced Science, EarlyView.
We developed a real‐time, label‐free, high‐throughput cell‐on‐a‐chip system based on a metasurface plasmon resonance colorimetric sensor (MetaSPRCS) to evaluate intestinal barrier function. This platform enables continuous monitoring of cell adhesion, proliferation, and barrier layer formation, disruption, and repair.
Youqian Chen, Wen Li, Jiaying Feng, Yue Shu, Yihui Yang, Yuyan Wang, Rui Li, Hanlin Zhou, Xinfan Yang, Yuxue Guo, Mingqian Chen, Wenjun Hu, Gang Logan Liu, Liping Huang, Yanan Li   +14 more
wiley   +1 more source

Endoplasmic reticulum stress enhances unsaturated fatty acid-induced hepatocyte injury in human pluripotent stem cell-derived hepatic culture. [PDF]

BMC Gastroenterol
Araki T, Yokoyama K, Ida K, Inagaki Y, Kamiya A.   +4 more
europepmc   +1 more source

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Kupffer Cell-Derived Interleukin-6 Aggravates Radiation-Induced Liver Disease by Activating Hepatocyte STAT3 to Promote <i>Ccng1</i> Transcription. [PDF]

Adv Radiat Oncol
Song X, Shao Y, Sun R, Jiang W, Chen Y, Liu M, Gu W, Zheng X, Jiang J.   +8 more
europepmc   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source

Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation. [PDF]

Gastro Hep Adv
Verzijl CRC, Struik D, Gerding A, Eilers RE, Thomas RE, Koster M, Langelaar-Makkinje M, Smit M, Huijkman N, Havinga R, Kloosterhuis N, Bloks VW, Wolters JC, de Boer JF, van de Sluis B, Bakker BM, Jonker JW.   +16 more
europepmc   +1 more source

Serum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki, Masahiro Ohira, Yuki Imaoka, Seiichi Simizu, Tomoyuki Abe, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Hideki Ohdan   +9 more
wiley   +1 more source

Road map for primary hepatocyte qualification in human liver organ models. [PDF]

BMC Methods
Varmazyad M, Gavlock DC, Castiglione MW, DeBiasio R, LaRocca G, Reese C, Vernetti LA, Schurdak M, Stern AM, Taylor DL, Miedel MT, Brown JA.   +11 more
europepmc   +1 more source