Results 271 to 280 of about 541,993 (403)

Bacterial lipopolysaccharide antagonizes transforming growth factor β1-induced apoptosis in primary cultures of hepatocytes [PDF]

, 1996
Paloma Martı́n-Sanz, María José Guerra Palmero, Marta Casado, Lisardo Boscá   +3 more
openalex   +1 more source

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

Advanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao, Yajie Peng, Hongyan Lei, Tianyi Wang, Huajuan Wang, Bo Wang, Jin Li, Xiaoying Li, Xuelian Xiong   +8 more
wiley   +1 more source

Hepatocyte SAMHD1 Deficiency Attenuates Hepatic Steatosis via Suppression of SREBP Activation in a Mouse Model of Metabolic-Associated Steatotic Liver Disease. [PDF]

Int J Biol Sci
Yin G, Liu Y, Teng X, Sun S, Chen B, Wang X, Yang T, Wang Y, Xu H, Chen YS, Gan G, Shen Y, Shao J.   +12 more
europepmc   +1 more source

Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment

, 2014
Davide Germano, Marianne Uteng, François Pognan, Salah‐Dine Chibout, Armin Wolf   +4 more
openalex   +1 more source

Higher Serum Hepatocyte Growth Factor Concentration is Associated with Better Preservation of GFR in Hemodialysis Patients [PDF]

, 2017
Ewa Baum, Beata Maćkowiak, Patrycja Sosińska, Krzysztof Pawlaczyk, Barbara Kołodziejczak, Andrzej Bręborowicz   +5 more
openalex   +1 more source

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Hepatology, 2014
A. Wree, A. Eguchi, Matthew D. McGeough, C. Peña, Casey D. Johnson, A. Canbay, H. Hoffman, A. Feldstein   +7 more
semanticscholar   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Hepatic adaptation to chronic metabolic stress primes tumorigenesis. [PDF]

Cell
Tzouanas CN, Shay JES, Sherman MS, Rubin AJ, Mead BE, Dao TT, Tao J, Lehrich BM, Eng G, Patterson-Fortin J, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong YE, Joung J, Chi F, McMahon-Skates T, Winston CL, Jeong WJ, Aney KJ, Chen E, Nissim S, Zhang F, Deshpande V, Monga SP, Lauer GM, Goessling W, Yilmaz ÖH, Shalek AK.   +33 more
europepmc   +1 more source

Biogenesis of Organelles and Membrane Proteins. [PDF]

, 1988
Harmey, Matthew A., Neupert, Walter, Nicholson, Donald W., Stuart, Rosemary A.   +3 more
core   +1 more source

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

Proceedings of the National Academy of Sciences of the United States of America, 1987
J. Gauldie, C. Richards, D. Harnish, P. Lansdorp, H. Baumann   +4 more
semanticscholar   +1 more source