Results 201 to 210 of about 334,700 (354)

Transcription Factors HNF1A, HNF4A, and FOXA2 Regulate Hepatic Cell Protein N-Glycosylation

Engineering
Hepatocyte nuclear factor 1 alpha (HNF1A), hepatocyte nuclear factor 4 alpha (HNF4A), and forkhead box protein A2 (FOXA2) are key transcription factors that regulate a complex gene network in the liver, creating a regulatory transcriptional loop.
Vedrana Vičić Bočkor, Nika Foglar, Goran Josipović, Marija Klasić, Ana Vujić, Branimir Plavša, Toma Keser, Samira Smajlović, Aleksandar Vojta, Vlatka Zoldoš   +9 more
doaj  

Isolation and Extraction of Gentian Polysaccharide and Its Protective Effect on Chemical Liver Injury

Food Safety and Health, EarlyView.
The water‐soluble polysaccharide GSBP‐N‐a‐1 with an average molecular weight of 3.82 kDa was successfully isolated and purified from Gentiana scabra. It was confirmed that the crude polysaccharides of Gentiana scabra could inhibit oxidative stress and inflammatory response by activating the Nrf2‐HO‐1 pathway, and significantly alleviate the chemical ...
Tianjiao Fu, Yan Dong, Guangxin Yuan
wiley   +1 more source

Purification and biochemical characterization of hepatocyte nuclear factor 2 involved in liver-specific transcription of the human alpha 1-antitrypsin gene.

, 1990
Vangipuram S. Rangan, Gautam Das
openalex   +1 more source

A Case of hepatocyte nuclear factor 1^|^alpha;-inactivated hepatocellular adenoma, involving anomalous portal tract, difficult to be differentiated from FNH-like lesion

, 2013
伊藤 勝彦, 近藤 福雄, 大多和 哲, 石井 隆之, Yoshiaki Shimizu, 小川 清, 岸 宏久, 小豆畑 康児, Masayuki Miyazaki   +8 more
openalex   +2 more sources

Papaverine attenuates the progression of alpha naphthylisothiocyanate induce cholestasis in rats

Current Research in Pharmacology and Drug Discovery
Cholestasis is a hepatobiliary condition that manifests as acute or chronic and results from disruptions in the bile flow, formation, or secretion processes.
Doaa Adnan Atshan, Munaf Hashim Zalzala
doaj  

Ginkgo biloba extract mitigates liver fibrosis and apoptosis by regulating p38 MAPK, NF-κB/IκBα, and Bcl-2/Bax signaling

Drug Design, Development and Therapy, 2015
Yuanyuan Wang, Rong Wang, Yujie Wang, Ruqin Peng, Yan Wu, Yongfang Yuan Department of Pharmacy, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Liver ...
Wang YY, Wang R, Wang YJ, Peng RQ, Wu Y, Yuan YF   +5 more
doaj  

Sucrase-Isomaltase Gene Expression Is Inhibited by Mutant Hepatocyte Nuclear Factor (HNF)-1.ALPHA. and Mutant HNF-1.BETA. in Caco-2 Cells

, 2006
Ning Gu, Tetsuya Adachi, Jun Takeda, Norihiko Aoki, Gozoh Tsujimoto, Akihiko Ishihara, Kinsuke Tsuda, Koichiro Yasuda   +7 more
openalex   +2 more sources

The Production of a Diabetic Mouse Using Constructs Encoding Porcine Insulin Promoter-Driven Mutant Human Hepatocyte Nuclear Factor-1.ALPHA.

, 2007
Masahito Watanabe, Kazuhiro Umeyama, Hiroomi Kawano, Naoko IZUNO, Hiroshi Nagashima, Keizaburo Miki   +5 more
openalex   +2 more sources

Lithocarpus polystachyus Rehd. leaves aqueous extract inhibits learning and memory impairment in Alzheimer's disease rats: Involvement of the SIRT6/NLRP3 signaling pathway

Ibrain, EarlyView.
The findings of this study demonstrate that STAE effectively counteracts the learning and memory impairment induced by Aβ25‐35 in rats. This effect is attributed, at least in part, to the regulation of the SIRT6/NLRP3 signaling pathway, which inhibits neuroinflammation and oxidative stress.
Wendan Wu, You Yan, Tingting Yi, Yu Wei, Jianmei Gao, Qihai Gong   +5 more
wiley   +1 more source

Constitutive Photomorphogenesis Protein 1 homolog (COP1) sustains nuclear factor-4 alpha function in human hepatocyte models [PDF]

Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
openalex   +1 more source