Results 201 to 210 of about 79,825 (316)

Sucrase-Isomaltase Gene Expression Is Inhibited by Mutant Hepatocyte Nuclear Factor (HNF)-1.ALPHA. and Mutant HNF-1.BETA. in Caco-2 Cells

, 2006
Ning Gu, Tetsuya Adachi, Jun Takeda, Norihiko Aoki, Gozoh Tsujimoto, Akihiko Ishihara, Kinsuke Tsuda, Koichiro Yasuda   +7 more
openalex   +2 more sources

Targeting sirtuin 1/nuclear factor erythroid 2-related factor 2/tumor necrosis factor-α pathway to modulate hepatic ischemia reperfusion-induced injury. [PDF]

World J Hepatol
Kelleni MT, Abdelzaher WY, Adly M, Attya ME, Fawzy MA, Ibrahim MA.   +5 more
europepmc   +1 more source

Targeting Ras homolog enriched in brain 1 to restore β-cell mass and function: A potential therapeutic strategy for diabetes. [PDF]

World J Diabetes
Peng Y, Zhang DD, Gan L, Zhang JQ.
europepmc   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 3 (MODY3) carrying a hepatocyte nuclear factor 1-alpha ( HNF1A ) mutation

, 2018
Frank Griscelli, Hélène Ezanno, Mathis Soubeyrand, Olivier Féraud, Noufϊssa Oudrhiri, Amélie Bonnefond, Ali G. Turhan, Philippe Froguel, Annelise Bennaceur‐Griscelli   +8 more
openalex   +1 more source

Nobiletin Attenuates Inflammation and Modulates Lipid Metabolism in an In Vitro Model of Intestinal Failure-Associated Liver Disease. [PDF]

Pharmaceutics
Belka M, Gostyńska-Stawna A, Sommerfeld-Klatta K, Stawny M, Krajka-Kuźniak V.   +4 more
europepmc   +1 more source

Prospective Comparison of DWI‐Derived Virtual MR Elastography and Conventional MR Elastography in Metabolic Dysfunction‐Associated Steatotic Liver Disease and Healthy Volunteers

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Virtual MR elastography (VMRE) and MRE have been proposed for liver fibrosis staging in metabolic dysfunction‐associated steatotic liver disease (MASLD), but VMRE's diagnostic performance remains debated. Purpose To assess the inter‐visit and inter‐reader reproducibility of fat‐uncorrected and fat‐corrected diffusion‐weighted ...
Anton Volniansky, Thierry L. Lefebvre, Merve Kulbay, Guillaume Gilbert, Boyan Fan, Justine Racette, Emmanuel Montagnon, Damien Olivié, Giada Sebastiani, Jeanne‐Marie Giard, Marie‐Pierre Sylvestre, Bich Ngoc Nguyen, Guy Cloutier, An Tang   +13 more
wiley   +1 more source

Hereditary Persistence of Alpha-Fetoprotein and Safe Application of Growth Hormone in Familial Short Stature: A Case Report. [PDF]

Am J Case Rep
Guo S, Zhang J, Chen Q, Yu Y, Ma H.
europepmc   +1 more source

Liver Progenitor Cells: Cellular Origins, Plasticity, and Signaling Pathways in Liver Regeneration. [PDF]

Biology (Basel)
Han J, Sung A, Jeong H, Jung Y.
europepmc   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source