Results 211 to 220 of about 334,700 (354)

Racing toward the future of chronic hepatitis B management: Achieving functional cure and enhancing hepatocellular carcinoma surveillance through precision medicine

Interdisciplinary Medicine, EarlyView.
Novel biomarker emergence plays a critical role in improving CHB management. Advances in sensitive detection methods, AI, and large‐scale data platforms have independently contributed to biomarkers while driving the development of multi‐omics approaches.
Yaru Shi, Rong Fan
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid [PDF]

, 2019
Kyoung‐Jae Won, Joo‐Seop Park, Hyunyoung Jeong   +2 more
openalex   +1 more source

Expression Profile of Serum CircFUNDC1 and CircUHRF1 Can Differentiate Between Colorectal Cancer and Inflammatory Bowel Diseases (Ulcerative Colitis and Crohn's Disease)

Journal of Clinical Laboratory Analysis, EarlyView.
(A) Post hoc pairwise comparisons between the four studied groups regarding the log2 of serum fold change of CircFUNDC1. There were significant differences between CRC, UC, or CD and controls. p values (Controls vs. UC = < 0.001, Controls vs. CD = < 0.001, Controls vs. CRC = < 0.001, UC vs. CD = 1.000, UC vs. CRC = 0.194, CD vs. CRC = 0.255).
Marwa A. Ali, Olfat G. Shaker, Eman M. Ezzat, Abeer A. Khalefa, Naglaa A. Ahmed, Raghda Yahia Abu El‐Ela, Amal A. Ibrahim Amin, Fatma Abdel Hamid Mohamed, Marwa Mamdouh Ahmed Abdelhafeez, Mohamed Saad Zaghloul Ahmed, Marwa N. AbdelHafez, Abdulrhman Khaled Al Abdulqader, Reham Fares   +12 more
wiley   +1 more source

<i>Bletilla striata</i> polysaccharides alleviate metabolic dysfunction-associated steatotic liver disease through enhancing hepatocyte RelA/ HNF1α signaling. [PDF]

World J Gastroenterol
He YH, Ou LL, Jiang JL, Chen YF, Abudukeremu A, Xue Y, Mu MY, Zhong WW, Xu DL, Meng XY, Guan YQ.   +10 more
europepmc   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

American Journal of Human Genetics, 2008
A. Reiner, M. Barber, Yongtao Guan, P. Ridker, L. Lange, D. Chasman, J. Walston, G. Cooper, N. Jenny, M. Rieder, J. P. Durda, Joshua D. Smith, J. Novembre, R. Tracy, J. Rotter, M. Stephens, D. Nickerson, R. Krauss   +17 more
semanticscholar   +1 more source

Standard Protocols for Characterising Primary and In Vitro-Generated Human Hepatocytes. [PDF]

J Cell Mol Med
Heydari Z, Gramignoli R, Piryaei A, Zahmatkesh E, Pooyan P, Seydi H, Nussler A, Szkolnicka D, Rashidi H, Najimi M, Hay DC, Vosough M.   +11 more
europepmc   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source