Results 271 to 280 of about 868,517 (361)
Traditional Chinese Medicine Properties and Microcalorimetry: BioScience Evaluation
ABSTRACT The properties theory of traditional Chinese medicine (TCM), characterized by cold, hot, warm, and cool four properties, is fundamental to its development, distinguishing it from natural, botanical, and chemical medicines. However, despite its significance, there is no unified theoretical definition, bioscientific characterization, or ...
Qiang Li+9 more
wiley +1 more source
Prognostic value of protein expression, tumor morphology and location within the pancreas in pancreatic ductal adenocarcinoma. [PDF]
Nishida H+4 more
europepmc +1 more source
The Hsp90β Isoform: An Attractive Target for Drug Development
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury+2 more
wiley +1 more source
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
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The Jieduan-Niwan Formula Reduces Inflammatory Responses in Acute-on-Chronic Liver Failure Rats by Inhibiting HMGB1-Induced Hepatocyte Pyroptosis. [PDF]
Hou W+7 more
europepmc +1 more source
PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis
Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
wiley +1 more source
Hepatocytes derived from human induced pluripotent stem cells: Towards establishing an <i>in vitro</i> model for assessing population variability in hepatotoxicity testing. [PDF]
Gao X+6 more
europepmc +1 more source
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela+5 more
wiley +1 more source