Results 281 to 290 of about 868,517 (361)

Inhibition of Cyclooxygenase-2 Upregulates the Nuclear Factor Erythroid 2-related Factor 2 Signaling Pathway to Mitigate Hepatocyte Ferroptosis in Chronic Liver Injury. [PDF]

J Clin Transl Hepatol
Yang Z, Tai Y, Lan T, Zhao C, Gao JH, Tang CW, Tong H.   +6 more
europepmc   +1 more source

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

Molecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez, Antonio Vico‐Padilla, Claus Schneider, Juan Carlos Espín, Antonio González‐Sarrías, Juan Antonio Giménez‐Bastida   +5 more
wiley   +1 more source

Differentiation of Wharton's jelly-derived mesenchymal stromal cells into hepatocyte-like cells using a refined method. [PDF]

BMC Mol Cell Biol
Afshari A, Azarpira N, Pakbaz S.
europepmc   +1 more source

Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter.

, 1994
Gary D. Wu, Li Chen, Kaj Forslund, Peter G. Traber   +3 more
openalex   +1 more source

Time‐course manganese chloride biodistribution and manganese‐induced MRI contrast in mouse organs

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose To optimize manganese‐enhanced MRI (MEMRI) in mice by profiling the time‐course biodistribution and associated T1 contrast enhancement of MnCl2 injected subcutaneously to avoid abrupt spikes in blood manganese levels. Methods Manganese (Mn) biodistribution and Mn‐induced T1 contrast in healthy female adult CD‐1 mice were investigated ...
Keyu Zhuang, Kyle D. W. Vollett, Minbo Hou, Yan Chang, Hai‐Ling Margaret Cheng   +4 more
wiley   +1 more source

Platelet aggregation elicits FasL expression and hepatocyte apoptosis in sinusoidal obstruction syndrome. [PDF]

Sci Rep
Higashi Y, Munesue S, Saeki M, Harashima A, Kimura K, Oshima Y, Takei R, Takada S, Nakanuma S, Makino I, Ohta T, Yagi S, Tajima H, Yamamoto Y.   +13 more
europepmc   +1 more source

The role of gut microbiota‐derived metabolites in neuroinflammation

Neuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

Role of HNF6 in liver homeostasis and pathophysiology. [PDF]

Mol Med
Tian M, Gao W, Ma S, Cao H, Zhang Y, An F, Qi J, Yang Z.   +7 more
europepmc   +1 more source

The Role of Magnesium in Liver Cirrhosis

Portal Hypertension &Cirrhosis, EarlyView.
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng, Xudan Wang, He Qi, Hongtao Tang, Xun Qi   +4 more
wiley   +1 more source

Ginseng and its functional components in non-alcoholic fatty liver disease: therapeutic effects and multi-target pharmacological mechanisms. [PDF]

Front Pharmacol
Xiao P, Ye Z, Li X, Feng Q, Su Y.
europepmc   +1 more source