Results 331 to 340 of about 628,453 (389)

iRhom2 regulates HMGB1 secretion to modulate inflammation and hepatocyte senescence in an in vitro model of ischemia-reperfusion injury. [PDF]

Cell Death Dis
Calligaris M, Perriera R, Carcione C, Miceli V, Pinto ML, Busà R, Amico G, Bulati M, Amato C, Pagano D, Conaldi PG, Scilabra SD, Pinzani M, Zito G.   +13 more
europepmc   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Convergent Metabolic Pathways in MASH Therapeutics: An AMPK-Centric Analysis. [PDF]

J Cell Mol Med
Choi S, Jung JS, Seo YS, Song S, Ham J, Chung H, Ramadan Y, Choi K.   +7 more
europepmc   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

The Role of Kupffer Cells and Liver Macrophages in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Biomedicines
Tsomidis I, Tsakou A, Voumvouraki A, Kouroumalis E.   +3 more
europepmc   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

Advanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo, Xiaoyan Guo, Jian Wei, Miaowen Jiang, Qifa Su, Xian Xia, Zhuozhou Li, Rong Cai, Jianguo Ma, Bo Fu, Ming Li, Jing Zhong, Lijun Xu, Xunming Ji   +13 more
wiley   +1 more source

Reconstruction and analysis of the gene network regulating apoptosis in hepatocellular carcinoma based on scRNA-seq data and the ANDSystem knowledge base. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Adamovskaya AV, Yatsyk IV, Kleshchev MA, Demenkov PS, Ivanisenko TV, Ivanisenko VA.   +5 more
europepmc   +1 more source

Are New Approach Methodologies (NAMs) the Holy Grail of toxicology? [PDF]

Toxicol Sci
Jaeschke H, Ramachandran A.
europepmc   +1 more source

Ascitic fluid concentrations of fibronectin and cholesterol [PDF]

, 1990
Gerbes, Alexander L., Jüngst, Dieter, Mezger, J., Xie, Yining   +3 more
core  

The crosstalk between fatty acid metabolism disorder and mitochondrial dysfunction is involved in hepatotoxicity co-induced by cadmium and molybdenum in ShaoXing duck (Anas platyrhyncha) livers. [PDF]

Poult Sci
Li S, Nie G, Dai X, Zhu J, Xiao L, Wang S, Chen J, Ren J, Zhang C.   +8 more
europepmc   +1 more source