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Biological Effects of Aqueous Extract of Laurus noboilis L. Leaves on Some Histological and Immunological Parameters in Male Rat Liver Affected by Aluminum Chloride [PDF]
Archives of Razi Institute, 2021 The present current study aimed to assess the protective effect of the aqueous extract of Laurus noboilis L. leaves against the toxic effects of aluminum chloride on liver tissue.
N Marza Hamza +2 more
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Frontiers in Bioengineering and Biotechnology, 2022 The liver is the most important metabolic hub of endo and xenobiotic compounds. Pre-clinical studies using rodents to evaluate the toxicity of new drugs and cosmetics may produce inconclusive results for predicting clinical outcomes in humans, moreover ...
Kayque Alves Telles-Silva +7 more
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Regenerative Medicine of Liver: Promises, Advances and Challenges
Biomimetics, 2021 Liver tissue engineering is a rapidly developing field which combines the novel use of liver cells, appropriate biochemical factors, and engineering principles, in order to replace or regenerate damaged liver tissue or the organ.
Saiful Ali +4 more
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Cells, 2021 Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to modulate the production and function of insulin-like growth factor ...
Mari C. Vázquez-Borrego +2 more
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Liver Organoids: Updates on Disease Modeling and Biomedical Applications
Biology, 2021 Liver organoids are stem cell-derived 3D structures that are generated by liver differentiation signals in the presence of a supporting extracellular matrix. Liver organoids overcome low complexity grade of bidimensional culture and high costs of in vivo
Carmen Caiazza +2 more
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Cells, 2020 The SRC kinase family comprises non-receptor tyrosine kinases that are ubiquitously expressed in all cell types. Although Src is reportedly activated in pulmonary and renal fibrosis, little is known regarding its role in liver fibrosis.
Hye-Young Seo +7 more
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Toxicological Analysis of Hepatocytes Using FLIM Technique: In Vitro versus Ex Vivo Models
Cells, 2021 The search for new criteria indicating acute or chronic pathological processes resulting from exposure to toxic agents, testing of drugs for potential hepatotoxicity, and fundamental study of the mechanisms of hepatotoxicity at a molecular level still ...
Svetlana Rodimova +8 more
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Antioxidants, 2023 Hepatotoxicity or drug-induced liver injury (DILI) is a major safety issue in drug development as a primary reason for drug failure in clinical trials and the main cause for post-marketing regulatory measures like drug withdrawal.
Estela Villanueva-Badenas +2 more
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Frontiers in Cell and Developmental Biology, 2020 Extracellular vesicles (EVs) are nano-sized membrane-limited organelles that are liberated from their producer cells, traverse the intercellular space, and may interact with other cells resulting in the uptake of the EV molecular payload by the recipient
Xinlei Li +4 more
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Hepatoprotective Effect of Solanum melongena/Eggplant against Acute Hepatitis
Althea Medical Journal, 2015 Background: Hepatitis is a liver inflammation that can be acute or chronic and may cause damage to hepatocytes such as necrosis.. Hepatocyte necrosis can be inhibited by antioxidants such as flavonoids found in Solanum melongena fruit.
Nabhan Komara +2 more
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