Results 31 to 40 of about 251,001 (160)
Extracellular Vesicles in the Development of the Non-Alcoholic Fatty Liver Disease: An Update
Biomolecules, 2020 Non-alcoholic fatty liver disease (NAFLD) is a broad spectrum of liver damage disease from a simple fatty liver (steatosis) to more severe liver conditions such as non-alcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. Extracellular vesicles (EVs)
Vicneswarry Dorairaj +3 more
doaj +1 more source
Cells, 2020 (1) Background: Platelets were postulated to constitute the trigger of liver regeneration. The aim of this study was to dissect the cellular interactions between the various liver cells involved in liver regeneration and to clarify the role of platelets.
Jeremy Meyer +7 more
doaj +1 more source
Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI
Journal of Lipid Research, 2012 To study the mechanisms of hepatic HDL formation, we investigated the roles of ABCA1, ABCG1, and SR-BI in nascent HDL formation in primary hepatocytes isolated from mice deficient in ABCA1, ABCG1, or SR-BI and from wild-type (WT) mice.
Ailing Ji +5 more
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HISTOLOGICAL AND HISTOCHEMICAL STUDY OF THE LIVER OF IRAQI LOCAL DUCKS [PDF]
Basrah Journal of Veterinary Research, 2015 The aim of study is provide basic data about the histological features of the liver of local Iraqi ducks and to study the glycogen content in the cytoplasm of the hepatocyte.
Maha Abd Al- Hadi Al- Abdulla
doaj +1 more source
Stabilisation of hepatocyte phenotype using synthetic materials [PDF]
, 2016 Primary human hepatocytes are a scare resource with limited lifespan and variable function which diminishes with time in culture. As a consequence, their use in tissue modelling and therapy is restricted.
Lucendo Villarin, Baltasar
core +1 more source
Journal of Biomechanical Science and Engineering, 2017 A sufficient number of functional live hepatocytes delivered to a recipient is necessary for cell therapy. Preventing cell viability loss during the cell injection process is important to improve the clinical outcomes of hepatocyte transplantation.
Sandi SUFIANDI +5 more
doaj +1 more source
T-2 Toxin Induces Oxidative Stress, Apoptosis and Cytoprotective Autophagy in Chicken Hepatocytes
Toxins, 2020 T-2 toxin is type A trichothecenes mycotoxin, which produced by fusarium species in cereal grains. T-2 toxin has been shown to induce a series of toxic effects on the health of human and animal, such as immunosuppression and carcinogenesis.
Huadong Yin +5 more
doaj +1 more source
Suitability of hepatocyte cell lines HepG2, AML12 and THLE-2 for investigation of insulin signalling and hepatokine gene expression [PDF]
Open Biology, 2018 Immortal hepatocyte cell lines are widely used to elucidate insulin-dependent signalling pathways and regulation of hepatic metabolism, although the often tumorigenic origin might not represent the metabolic state of healthy hepatocytes.
Stephanie Sefried +3 more
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Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]
, 2015 TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Dunbar, Donald R +4 more
core +1 more source
Biology Open, 2020 Non-alcoholic fatty liver disease (NAFLD) affects 30–40% of adults and 10% of children in the US. About 20% of people with NAFLD develop non-alcoholic steatohepatitis (NASH), which may lead to cirrhosis and liver cancer, and is projected to be a leading ...
Igor Gurevich +6 more
doaj +1 more source