Results 21 to 30 of about 200,012 (263)
Frontiers in Toxicology, 2022 In the pharmaceutical industry, primary cultured hepatocytes is a standard tool used to assess hepatic metabolisms and toxicity in vitro. Drawbacks, however, include their functional deterioration upon isolation, mostly due to the lack of a physiological
Masaki Nishikawa +12 more
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The Journal of Poultry Science, 2005 This study was carried out to investigate the effects of low oral doses of o, p’-DDT on the reproductive parameters and liver histology in adult male Japanese quail over a long period (120 days).
Rania El-Gawish, Teruo Maeda
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Hepatocyte Transplantation [PDF]
Journal of Clinical and Experimental Hepatology, 2011 Hepatocyte transplantation (HTx) has been developed for use in liver-based metabolic disorders and in acute liver failure. Worldwide, there are around 80 patients that have been transplanted with hepatocytes. Almost all reported studies prove feasibility and safety of the procedure with short- to medium-term success.
Ragai R, Mitry +2 more
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The Journal of Poultry Science, 2019 The effects of insulin-like growth factor binding protein 2 (IGFBP2) on the expression of fatty acid synthesis regulators and triglyceride production were investigated in primary cultured chicken hepatocytes.
Yanshuang Mu +6 more
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Frontiers in Cell and Developmental Biology, 2021 Sterol response element binding protein (SREBP) is a master regulator of cellular lipogenesis. One key step in the regulation of SREBP activity is its sequential cleavage and trans-location by several different proteinases including SREBP cleavage ...
Ming Kong +6 more
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β-Arrestin 2 Promotes Hepatocyte Apoptosis by Inhibiting Akt Pathway in Alcoholic Liver Disease
Frontiers in Pharmacology, 2018 Alcoholic liver disease (ALD) is a complex process that includes a wide range of hepatic lesions, from steatosis to cirrhosis, and even hepatocellular carcinoma (HCC).
Ying-Yin Sun +5 more
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eLife, 2020 The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
Arely V Diaz, Tânia Reis
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Hepatitis E Virus Induces Hepatocyte Apoptosis via Mitochondrial Pathway in Mongolian Gerbils
Frontiers in Microbiology, 2018 Previous studies demonstrated that Mongolian gerbils can be infected by hepatitis E virus (HEV), which induces the hepatic injury. Here, the mitochondria in hepatocytes from HEV-infected gerbils were considerably swollen, thin cristae.
Yifei Yang +6 more
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Inhibiting Liver Autophagy and Promoting Hepatocyte Apoptosis by Schistosoma japonicum Infection
Tropical Medicine and Infectious DiseaseWe established a mouse model of Schistosoma japonicum infection in order to study the effects of the infection on hepatocyte autophagy and apoptosis. We also stimulated HepG2 cells with soluble egg antigens (SEA) in vitro.
Zhihao Yu +5 more
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Frontiers in Physiology, 2017 In the liver tumor necrosis factor (TNF)-induced signaling critically regulates the immune response of non-parenchymal cells as well as proliferation and apoptosis of hepatocytes via activation of the NF-κB and JNK pathways.
Federico Pinna +9 more
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