Human Liver Sinusoid on a Chip for Hepatitis B Virus Replication Study
Micromachines, 2017 We have developed a miniature human liver (liver-sinusoid-on-a-chip) model using a dual microchannel separated by a porous membrane. Primary human hepatocytes and immortalized bovine aortic endothelial cells were co-cultured on opposite sides of a ...
Young Bok (Abraham) Kang +4 more
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Cellular destruction in primary cultured hepatocyte cells in Epinephelus coioides in expose to Nonylphenol [PDF]
بومشناسی آبزیان, 2019 The present study aimed to use the primary hepatocyte culture of orang spotted grouper, Epinephlus coioides for assessing the toxic effects of nonylphenol (NP) on the primary hepatocyte viability and hepatocyte damage.
Negin Derakhshesh +4 more
doaj
Low-dose recombinant human hepatocyte growth factor enhances effect of hepatocyte transplantation in rats treated with retrorsine. [PDF]
, 2009 BACKGROUND/AIMS: The aim of this study was to regenerate transplanted hepatocytes selectively in a recipient using retrorsine and recombinant human hepatocyte growth factor (rhHGF). METHODOLOGY: Nagase analbuminemic rats (NARs) received pretreatment with
Takatsuki, Mitsuhisa +9 more
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Short-term fenofibrate treatment improves ultrastructure of hepatocytes of old rats
Folia Histochemica et Cytobiologica, 2021 INTRODUCTION: Fenofibrate (FN) is a hypolipemic drug used for the treatment of mixed dyslipidemia. Since in our previous study FN administration to young and old rats adversely affected the serum activity of liver marker enzymes, we decided to examine ...
Adrian Zubrzycki +3 more
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Hepatocyte transplantation in animal models.: Hepatocyte transplantation in animals models
, 2009 International audienceMore than 30 years after the first hepatocyte transplant to treat the Gunn rat, the animal model for Crigler-Najjar syndrome, there are still a number of impediments to hepatocyte transplantation.
Weber, Anne +3 more
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An investigation of Cytochrome P450 function in human cell Lines for potential use in a bioartificial liver device [PDF]
, 2010 Bioartificial Liver Devices (BAL) could provide hepatic function in patients with liver failure awaiting transplantation or liver regeneration. Certain BALs use human hepatoblastoma-derived HepG2 cells that can perform many hepatocyte specific ...
Thomas, A.
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The fate of hepatocyte cell line derived from a liver injury model with long-term in vitro passage
, 2018 Backgrounds: Orthotopic Liver Transplantation (OLT) is the therapy of choice for the treatment of end-stage liver disease, but the severe shortage of organ donors, complex and expensive surgical procedure and increased mortality of prospective organ ...
Chand, Lokendra +6 more
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Journal of Extracellular BiologyWhile significant progress has been made in understanding various aspects of liver regeneration, the molecular mechanisms responsible for the initiation and termination of cell proliferation in the liver following massive tissue loss or injury of liver ...
Mina McGinn +3 more
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Plasmodium cellular effector mechanisms and the hepatic microenvironment
Frontiers in Microbiology, 2015 Plasmodium falciparum malaria remains one of the most serious health problems globally. Immunization with attenuated parasites elicits multiple cellular effector mechanisms capable of eliminating Plasmodium liver stages.
Ute eFrevert, Urszula eKrzych
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HISTORICAL ASPECTS OF HEPATOCYTE TRANSPLANTATION
, 2006 Hepatocyte transplantation has been used for temporary metabolic support of patients in end-stage liver failure awaiting whole organ transplantation as a method to support liver function and facilitate regeneration of the native liver in cases of ...
BRUZZONE, Paolo
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